Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yusuke Hanaki"'
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101512- (2024)
Vitex rotundifolia is a folk medicinal plant that has been used to treat various diseases. We have previously found that the extract of its leaves shows cytotoxic and epithelial mesenchymal transition inhibitory effect in HHUA endometrial cells. In t
Externí odkaz:
https://doaj.org/article/b019b305a31645419d12b844a2520a08
Publikováno v:
Clinical Case Reports, Vol 9, Iss 11, Pp n/a-n/a (2021)
Abstract Urgent response is required in suspected pulmonary tuberculosis (PTB) cases for infection control, and chest image is the first step to suspect PTB. This case shows an unexpected exception and importance of molecular testing for definite dia
Externí odkaz:
https://doaj.org/article/be14621595824585803fd9a9f0f34790
Autor:
Weina Jiang, Satoshi Tan, Yusuke Hanaki, Kazuhiro Irie, Hajime Uchida, Ryuichi Watanabe, Toshiyuki Suzuki, Bryan Sakamoto, Michiya Kamio, Hiroshi Nagai
Publikováno v:
Marine Drugs, Vol 12, Iss 12, Pp 5788-5800 (2014)
The toxin-producing cyanobacterium, Moorea producens, is a known causative organism of food poisoning and seaweed dermatitis (also known as “swimmer’s itch”). Two new toxic compounds were isolated and structurally elucidated from an ethyl aceta
Externí odkaz:
https://doaj.org/article/f1b1b3369abb4f94885663a88d602634
Autor:
Jumpei Maki, Yusuke Hanaki, Yanagita, Ryo C., Masayuki Kikumori, Anastasiia Kovba, Ayaka Washizaki, Chihiro Tsukano, Hirofumi Akari, Kazuhiro Irie
Publikováno v:
Bioscience, Biotechnology & Biochemistry; Dec2023, Vol. 87 Issue 12, p1453-1461, 9p
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 86:1417-1422
HHUA endometrial adenocarcinoma cells aggregated into spheroids when cultured on collagen type I gels. 12-O-Tetradecanoylphorbol 13-acetate, a PKC activator, disassembled the spheroids through epithelial–mesenchymal transition and increased their p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77992d5316c5be77204f08664bb667d7
https://doi.org/10.1093/bbb/zbac136
https://doi.org/10.1093/bbb/zbac136
Autor:
Tomoki Sekido, Kosuke Yamamoto, Ryo C. Yanagita, Yasuhiro Kawamani, Yusuke Hanaki, Kazuhiro Irie
Publikováno v:
Bioorganicmedicinal chemistry. 73
A simplified analog (3) of aplysiatoxin was synthesized. Compound 3 has only one tetrahydropyran ring at positions 3-7, the A-ring of the spiroketal moiety, which is the conformation-controlling unit for the macrolactone ring. Nuclear magnetic resona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c78475f25043156e6ef2c3b6cc1ebb
https://pubmed.ncbi.nlm.nih.gov/36113282
https://pubmed.ncbi.nlm.nih.gov/36113282
Publikováno v:
Fundamental Toxicological Sciences. 8:69-73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0774f226cf09420db0a7418260bb623c
https://doi.org/10.2131/fts.8.69
https://doi.org/10.2131/fts.8.69
Autor:
Yoshiyuki Suzuki, Keiichi Moritoki, Mizuki Kajiwara, Ryo C Yanagita, Yasuhiro Kawanami, Yusuke Hanaki, Kazuhiro Irie
Publikováno v:
Bioscience, biotechnology, and biochemistry. 86(8)
Simplified analogs of aplysiatoxin (ATX) such as 10-Me-aplog-1 exhibit potent antiproliferative activity toward human cancer cell lines by activating protein kinase C (PKC). However, the synthesis of 10-Me-aplog-1 involved a 23-step longest linear se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0d8ffc529f2cbe9a1f371c7e349f5a
https://pubmed.ncbi.nlm.nih.gov/35648459
https://pubmed.ncbi.nlm.nih.gov/35648459
Autor:
Benjamin J. Huffman, Yusuke Hanaki, Tiffany Chu, Jonathan L. Wong, Ryan A. Shenvi, K. N. Houk, Shuming Chen
Publikováno v:
Angewandte Chemie (International ed. in English), vol 61, iss 3
Angew Chem Int Ed Engl
Angew Chem Int Ed Engl
A strategy to control the diastereoselectivity of bond formation at a prochiral attached-ring bridgehead is reported. An unusual stereodivergent Michael reaction relies on basic vs. Lewis acidic conditions and non-covalent interactions to control re-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577fa59f67cd0dd4a3aed9911a577401
https://doi.org/10.1002/ange.202114514
https://doi.org/10.1002/ange.202114514
Autor:
Yoshihiko Nokura, Kazuhiro Irie, Koutaro Hayakawa, Masaki Kita, Atsuo Nakazaki, Toshio Nishikawa, Yusuke Araki, Yusuke Hanaki
Publikováno v:
Bioscience, biotechnology, and biochemistry. 85(6)
Oscillatoxins (OTXs) and aplysiatoxins are biosynthetically related polyketides produced by marine cyanobacteria. We previously developed a synthetic route to phenolic O-methyl analogs of OTX-D and 30-methyl-OTX-D during collective synthesis of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece7d02bab61d2641b61711d91dbd9d1
https://pubmed.ncbi.nlm.nih.gov/33851985
https://pubmed.ncbi.nlm.nih.gov/33851985