Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yusuke Aratsu"'
Autor:
Kouki Watanabe, Reo Odagiri, Sawako Shindo, Takamitsu Sasaki, Yusuke Aratsu, Rie Shoji, Takeshi Kumagai, Kiyoshi Nagata
Publikováno v:
Fundamental Toxicological Sciences. 4:229-239
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bad8dc35c78e495341a261a3224e577
https://doi.org/10.2131/fts.4.229
https://doi.org/10.2131/fts.4.229
Autor:
Ryosuke Sugawara, Kiyoshi Nagata, Takamitsu Sasaki, Shinichi Miyairi, Yusuke Aratsu, Takeshi Kumagai
Publikováno v:
Drug Metabolism and Pharmacokinetics. 31:139-145
Ban-Lan-Gen is the common name for the dried roots of indigo plants, including Polygonum tinctorium, Isatis indigotica, Isatis tinctoria, and Strobilanthes cusia. Ban-Lan-Gen is frequently used as an anti-inflammatory and an anti-viral for the treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249418218a64cd9a06a284b671533f3e
https://doi.org/10.1016/j.dmpk.2016.01.002
https://doi.org/10.1016/j.dmpk.2016.01.002
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:S42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd5cff234944c1d2a5bfc04f67808993
https://doi.org/10.1016/j.dmpk.2020.04.067
https://doi.org/10.1016/j.dmpk.2020.04.067
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:S42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a39f0f6b2c66f94aa8af06f21ffb4c3b
https://doi.org/10.1016/j.dmpk.2018.09.154
https://doi.org/10.1016/j.dmpk.2018.09.154
Autor:
Naoki Miyagawa, Kota Asahina, Shintaro Hirashima, Scott Thacher, Satoki Doi, Masayuki Kotoku, Yukihiro Nomura, Katsuya Maeda, Shingo Obika, Haiyan Tao, Erin Bradley, Yoshiaki Katsuda, Paul Crowe, Seki Noriyoshi, Ruo Steensma, Takahiro Hata, Tsuyoshi Adachi, Robert Babine, Sakai Takayuki, Makoto Shiozaki, Kojo Arita, Masato Noguchi, Takaki Maeba, Xiaolin Li, Yasunori Hase, Morgan Fenn, Kazuyuki Hirata, Masafumi Kamada, Yusuke Aratsu, Akimi Hori, Takayuki Yamaguchi, Hiromasa Hashimoto
A novel series of RORγ inhibitors was identified starting with the HTS hit 1. After SAR investigation based on a prospective consideration of two drug-likeness metrics, ligand efficiency (LE) and fraction of sp(3) carbon atoms (Fsp(3)), significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a980bfa040ac0bdac6e9c6c9a5fd8c0
https://europepmc.org/articles/PMC4716592/
https://europepmc.org/articles/PMC4716592/
Autor:
Shinichi Kume, Jun Nishiu, Yasuhiro Ohe, Shinji Yata, Hiromi Hamada, Shin-ichi Oshida, Kenji Yamanaka, Yukihito Ishii, Makoto Kakutani, Hideyuki Taniuchi, Yusuke Aratsu, Hironobu Tadaki, Chihiro Okuma, Takeshi Ohta, Tomohiro Oda
Publikováno v:
European journal of pharmacology. 758
Monoacylglycerol acyltransferase 2 (MGAT2) plays an important role in intestinal fat absorption. We discovered the novel MGAT2 inhibitor, JTP-103237, and evaluated its pharmacological profile. JTP-103237 selectively inhibited MGAT2 without remarkable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da9f9f0e7446f145f91820263459325
https://pubmed.ncbi.nlm.nih.gov/25857225
https://pubmed.ncbi.nlm.nih.gov/25857225