Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Yusuke Akagi"'
Autor:
Hayato Nakagawa, Atsushi Kittaka, Yusuke Akagi, Shigeyuki Kurosaki, Sayuri Mototani, Lisa Asano, Aileen Mendoza, Yasushi Takemoto, Kenjiro Kotake, Yuki Hayata, Kazuo Nagasawa, Motonari Uesugi, Satoshi Kawamura, Fumihiro Kawagoe
Publikováno v:
Journal of Medicinal Chemistry. 64:5689-5709
Vitamin D3 metabolites inhibit the expression of lipogenic genes by impairing sterol regulatory element-binding protein (SREBP), a master transcription factor of lipogenesis, independent of their canonical activity through a vitamin D receptor (VDR).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6539da680f4c06f349688a342b53501a
https://doi.org/10.1021/acs.jmedchem.0c02179
https://doi.org/10.1021/acs.jmedchem.0c02179
Autor:
Tomoyasu Tachibana, Naoki Akisada, Yasuharu Sato, Munechika Tsumura, Yusuke Akagi, Kazunori Nishizaki, Soshi Takao, Yuka Gion, Yorihisa Orita, Kohei Nishimoto, Tadashi Yoshino, Hidenori Marunaka, Tomohiro Toji, Takuma Makino, Kentaro Miki
Publikováno v:
Medical Molecular Morphology. 54:52-59
Immune checkpoint proteins programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) are important therapeutic targets for head and neck cancer. This large-scale case study aimed to analyze tongue squamous cell carcinomas (SCCs) and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d3653476ba2eea415ee0d1802862d4
https://doi.org/10.1007/s00795-020-00261-7
https://doi.org/10.1007/s00795-020-00261-7
Publikováno v:
Chemical and Pharmaceutical Bulletin. 68:288-291
We report a Pd-catalyzed β-arylation of cyclic α,β-unsaturated O-methyl oximes with aryl iodides. This reaction shows complete regioselectivity and excellent functional group tolerance. β-Arylation of 2-cyclohexen-1-one O-methyl oxime (existing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbdd243075c5ddbb0c0b90036fba100c
https://doi.org/10.1248/cpb.c19-01012
https://doi.org/10.1248/cpb.c19-01012
Autor:
Kentaro Miki, Yuka Gion, Hidenori Marunaka, Naoki Akisada, Tadashi Yoshino, Takuma Makino, Tomoyasu Tachibana, Soshi Takao, Yorihisa Orita, Yasuharu Sato, Yusuke Akagi, Kazunori Nishizaki
Publikováno v:
Japanese Journal of Clinical Oncology. 50:392-398
Background Metastasis-associated in colon cancer 1 (MACC1) has been reported to be an independent indicator of poor prognoses in some kinds of cancer due to disease metastasis or recurrence. We investigated the correlation between MACC1 expression an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bc40a9962669eac9fcb18ce44f8c30
https://doi.org/10.1093/jjco/hyz206
https://doi.org/10.1093/jjco/hyz206
Autor:
Akiko Nagata, Shadi Sedghi Masoud, Aileen Mendoza, Fumihiro Kawagoe, Kazuo Nagasawa, Kosuke Usuda, Yasushi Takemoto, Kenjiro Kotake, Lisa Asano, Motonari Uesugi, Yusuke Akagi, Atsushi Kittaka, Koji Yasui
Publikováno v:
ACS chemical biology. 14(12):2851-2858
Vitamin D3 metabolites are capable of controlling gene expression in mammalian cells through two independent pathways: vitamin D receptor (VDR) and sterol regulatory element-binding protein (SREBP) pathways. In the present study, we dissect the compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb4978efeb1730dddec3596b072af0e
http://hdl.handle.net/2433/252796
http://hdl.handle.net/2433/252796
Autor:
Takeshi Akisada, Ayako Takeuchi, Tokio Wakabayashi, Aki Fukumoto, Yusuke Akagi, Sohei Kajiwara, Hisashi Ishihara, Masako Uno, Naoki Akisada
Publikováno v:
Okayama Igakkai Zasshi (Journal of Okayama Medical Association). 131:145-152
To clarify the scenario regarding the emergency medical treatment of patients undergoing otolaryngology in southeastern Okayama Prefecture in Japan, we evaluated the conditions in three hospitals that mainly provide emergency medical treatment to pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354d0740b3b5f67b50d9da497eca4ba4
https://doi.org/10.4044/joma.131.145
https://doi.org/10.4044/joma.131.145
Publikováno v:
Asian Journal of Organic Chemistry. 10:1094-1096
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed492971d7a61eddcc8a769647fd3ded
https://doi.org/10.1002/ajoc.202100142
https://doi.org/10.1002/ajoc.202100142
Autor:
Kentaro Miki, Kazunori Nishizaki, Naoki Akisada, Hidenori Marunaka, Tadashi Yoshino, Yusuke Akagi, Yuka Gion, Yasuharu Sato, Yorihisa Orita, Takuma Makino, Tomoyasu Tachibana
Publikováno v:
Acta Oto-Laryngologica. 139:647-651
Background: p16INK4a (p16) expression in tongue cancer (TC) is reportedly not associated with human papilloma virus (HPV). Mutations of KRAS in cancer cells are most frequently observed within codon 12. However, few reports have investigated the asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2af5176d2d8a5362c43d4812bc64efd9
https://doi.org/10.1080/00016489.2019.1610574
https://doi.org/10.1080/00016489.2019.1610574
Autor:
Tadashi Yoshino, Kana Ikegami, Yorihisa Orita, Tomoyasu Tachibana, Takuma Makino, Kazunori Nishizaki, Kentaro Miki, Toshihiro Ito, Yuka Gion, Yasuharu Sato, Munechika Tsumura, Hidenori Marunaka, Naoki Akisada, Yusuke Akagi
Publikováno v:
Acta Oto-Laryngologica. 139:80-84
Long-term smoking and drinking are known to contribute to the onset of tongue cancer (TC). However, the increasing incidence of TC in younger adults has been suggested to be associated with other factors.The present study investigated the relationshi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18eff4f39ba84bf2503f7f23ffccd723
https://doi.org/10.1080/00016489.2018.1541506
https://doi.org/10.1080/00016489.2018.1541506