Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yusuf T Abaci"'
Autor:
Seth R Taylor, Mariko Kobayashi, Antonietta Vilella, Durgesh Tiwari, Norjin Zolboot, Jessica X Du, Kathryn R Spencer, Andrea Hartzell, Carol Girgiss, Yusuf T Abaci, Yufeng Shao, Claudia De Sanctis, Gian Carlo Bellenchi, Robert B Darnell, Christina Gross, Michele Zoli, Darwin K Berg, Giordano Lippi
Publikováno v:
eLife, Vol 12 (2023)
The assembly of the mammalian brain is orchestrated by temporally coordinated waves of gene expression. Post-transcriptional regulation by microRNAs (miRNAs) is a key aspect of this program. Indeed, deletion of neuron-enriched miRNAs induces strong d
Externí odkaz:
https://doaj.org/article/b595d3de11dc4474b897975c00e26573
Autor:
Tunahan Ergünay, Özgecan Ayhan, Arda B Celen, Panagiota Georgiadou, Emre Pekbilir, Yusuf T Abaci, Duygu Yesildag, Mandy Rettel, Ulduz Sobhiafshar, Anna Ogmen, NC Tolga Emre, Umut Sahin
Publikováno v:
Life Science Alliance
Cas9 is sumoylated and ubiquitylated in human cells. K848 is the major SUMO2/3 modification site, but multiple lysines are ubiquitylated, precipitating proteasomal degradation. Preventing Cas9 sumoylation by K848 ablation or by pharmacologic means re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21719ae127bd87ee5aec82d13f6fa3e8
https://doi.org/10.26508/lsa.202101078
https://doi.org/10.26508/lsa.202101078
Autor:
Tarig Bashir, Harun Öztürk, Florence Meyer-Losic, Gisele Mautino, Florence Jollivet, Serge Auvin, Umut Sahin, Yusuf T Abaci
Publikováno v:
Life Science Alliance
A new molecule induces AR sumoylation and degradation resulting in selective growth inhibition in AR-dependent prostate cancer cells, but its activity is blunted by interference with proteasomes.
Aberrant androgen signaling drives prostate cance
Aberrant androgen signaling drives prostate cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad28fb69efe3afa7ec3c635b072d625e
https://doi.org/10.26508/lsa.201800213
https://doi.org/10.26508/lsa.201800213