PAD2 dysregulation and aberrant protein citrullination feature prominently in reactive astrogliosis and myelin protein aggregation in sporadic ALS

Autor: Yusuf, Issa O., Parsi, Sepideh, Ostrow, Lyle W., Brown, Robert H., Thompson, Paul R., Xu, Zuoshang

Publikováno v: In Neurobiology of Disease March 2024 192

Additional file 2 of Protein citrullination marks myelin protein aggregation and disease progression in mouse ALS models

Autor: Yusuf, Issa O., Qiao, Tao, Parsi, Sepideh, Tilvawala, Ronak, Thompson, Paul R., Xu, Zuoshang

Additional file 2: Figure S1. Citrullinated proteins accumulate as foci in reactive astroglia (dotted circles) in early disease stages and become widespread in late disease stages in ALS mouse models. (A, B) Double immunofluorescence staining for GFA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de2266184d95c9c9c77700d33be7156

Exposure to prolonged unpredictable light impairs spatial memory via induction of oxidative stress and tumor necrosis factor-alpha in rats.

Autor: Faborode, Oluwaseun S., Yusuf, Issa O., Okpe, Paschal O., Okudaje, Ann O., Onasanwo, Samuel A.

Publikováno v: Journal of Basic & Clinical Physiology & Pharmacology; May2022, Vol. 33 Issue 3, p355-362, 8p

RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability.

Autor: Provasek VE; Division of DNA Repair Research within the Center for Neuroregeneration, Department of Neurosurgery, Houston Methodist Research Institute, Houston, TX 77030, USA.; School of Medicine, Texas A&M University, College Station, TX 77843, USA., Bacolla A; Department of Molecular and Cellular Oncology, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Rangaswamy S; Division of DNA Repair Research within the Center for Neuroregeneration, Department of Neurosurgery, Houston Methodist Research Institute, Houston, TX 77030, USA., Mitra J; Division of DNA Repair Research within the Center for Neuroregeneration, Department of Neurosurgery, Houston Methodist Research Institute, Houston, TX 77030, USA., Kodavati M; Division of DNA Repair Research within the Center for Neuroregeneration, Department of Neurosurgery, Houston Methodist Research Institute, Houston, TX 77030, USA., Yusuf IO; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA., Malojirao VH; Division of DNA Repair Research within the Center for Neuroregeneration, Department of Neurosurgery, Houston Methodist Research Institute, Houston, TX 77030, USA., Vasquez V; Division of DNA Repair Research within the Center for Neuroregeneration, Department of Neurosurgery, Houston Methodist Research Institute, Houston, TX 77030, USA., Britz GW; Division of DNA Repair Research within the Center for Neuroregeneration, Department of Neurosurgery, Houston Methodist Research Institute, Houston, TX 77030, USA.; Department of Neurosurgery and Department of Neuroscience, Weill Cornell Medical College, New York, NY 10065, USA., Li GM; Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Xu Z; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA., Mitra S; Division of DNA Repair Research within the Center for Neuroregeneration, Department of Neurosurgery, Houston Methodist Research Institute, Houston, TX 77030, USA., Garruto RM; Department of Biological Sciences, Binghamton University, State University of New York, Binghamton, NY 13902., Tainer JA; Department of Molecular and Cellular Oncology, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Hegde ML; Division of DNA Repair Research within the Center for Neuroregeneration, Department of Neurosurgery, Houston Methodist Research Institute, Houston, TX 77030, USA.; Department of Neuroscience, Weill Cornell Medical College, New York, NY 10065, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 08. Date of Electronic Publication: 2024 Nov 08.