Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yusoo Lee"'
Autor:
Ashley M. Mello, Tenzin Ngodup, Yusoo Lee, Katelyn L. Donahue, Jinju Li, Arvind Rao, Eileen S. Carpenter, Howard C. Crawford, Marina Pasca di Magliano, Kyoung Eun Lee
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-9 (2022)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is characterized by an extensive fibroinflammatory stroma and often experiences conditions of insufficient oxygen availability or hypoxia. Cancer-associated fibroblasts (CAF) are a predominant and hete
Externí odkaz:
https://doaj.org/article/58ecf0cb5fb64401ae4dd519669818f1
Autor:
Tae Min Kim, Dae Seog Heo, Seongyeol Park, So Yeon Kim, Yoon Kyung Jeon, Yusoo Lee, Miso Kim, Bhumsuk Keam, Young Seok Ju, Dong Wan Kim, Ha Ram Park
Publikováno v:
Journal of Thoracic Oncology. 16:1859-1871
Introduction EGFRT790M mostly exists subclonally and is acquired as the most common mechanism of resistance to EGFR tyrosine kinase inhibitors (TKIs). Nevertheless, because de novo EGFRT790M-mutant NSCLC is rare, little is known on acquired resistanc
Autor:
Ha-Ram, Park, Tae Min, Kim, Yusoo, Lee, Soyeon, Kim, Seongyeol, Park, Young Seok, Ju, Miso, Kim, Bhumsuk, Keam, Yoon Kyung, Jeon, Dong-Wan, Kim, Dae Seog, Heo
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 16(11)
EGFRAcquired resistance mechanisms were analyzed using tumor and plasma samples before and after third-generation EGFR TKI treatment in four patients with de novo EGFROf seven patients with NSCLC with de novo EGFRActivation of bypass pathways and the
Autor:
Ja-Lok Ku, So Yeon Kim, Dong Wan Kim, Miso Kim, Dae Seog Heo, Tae Min Kim, Bhumsuk Keam, Yusoo Lee
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 14(9)
Introduction NSCLC with EGFR exon 20 insertion mutations is the third most common type of EGFR-mutant NSCLC and is resistant to EGFR tyrosine kinase inhibitors (TKIs). This study was conducted to evaluate the efficacies of first- to third-generation
Autor:
So Yeon Kim, Yusoo Lee, Miso Kim, Bhumsuk Keam, Dong Wan Kim, Jaemoon Koh, Su Jung Kim, Yoon Kyung Jeon, Dae Seog Heo, Tae Min Kim
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose The purpose of this study was to evaluate the relationships between the resistance of anaplastic lymphoma kinase (ALK)‒positive non-small cell lung cancer (NSCLC) to ALK inhibitors and the programmed cell death-1/programmed cell death-ligan
Autor:
Dae Seog Heo, Yusoo Lee, Yoon Kyung Jeon, Tae Min Kim, Chan Young Ock, Dong Wan Kim, Ha-Ram Park, Miso Kim, So Yeon Kim, Bhumsuk Keam
Publikováno v:
Cancer Research. 79:3032-3032
Background: Epidermal growth factor receptor (EGFR) T790M mutation is well known as primary and acquired resistance mechanisms to the 1st and 2nd generation EGFR tyrosine kinase inhibitors (TKIs). However, a de novo and clonal EGFR T790M mutation is
Autor:
Dae Seog Heo, Bhumsuk Keam, Tae Min Kim, Yong-Oon Ahn, Yusoo Lee, Miso Kim, So Yeon Kim, Dong Wan Kim
Publikováno v:
Clinical Cancer Research. 24:B27-B27
Background: Although EGFR exon 20 insertion mutation is the third most common among EGFR-mutant NSCLC, this mutation has not been well studied and the first-generation EGFR TKIs are ineffective. In addition, the efficacy of the third-generation EGFR
Autor:
Su-Jung Kim, Soyeon Kim, Dong-Wan Kim, Miso Kim, Bhumsuk Keam, Tae Min Kim, Yusoo Lee, Jaemoon Koh, Yoon Kyung Jeon, Dae Seog Heo
Publikováno v:
Cancer Research & Treatment; Jul2019, Vol. 51 Issue 3, p1231-1240, 10p
Autor:
Yong-Oon Ahn, Bhumsuk Keam, Miso Kim, Tae Min Kim, So Yeon Kim, Dae Seog Heo, Yusoo Lee, Dong Wan Kim
Publikováno v:
Cancer Research. 77:3157-3157
Background: Although EGFR exon 20 insertion mutation is the third most common among EGFR-mutant NSCLC, this mutant clones are resistant to the first-generation EGFR TKIs. In addition, the efficacy of the second or third-generation EGFR TKIs is unknow