Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yushi Matsuo"'
Autor:
Naofumi Uesato, Takahiro Hata, Takayuki Yamaguchi, Yushi Matsuo, Kazutaka Ikegashira, Koji Inagaki, Naoki Miyagawa, Mutsuyoshi Matsushita, Yoshihiro Kitagawa, Reina Kakefuda
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1884-1892
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and structural destruction of the joints. Bone damage occurs in an early stage after onset and osteoclast activation plays a substantial role in its prog
Autor:
Mutsuyoshi Matsushita, Kazutaka Ikegashira, Reina Kakefuda, Yushi Matsuo, Naofumi Uesato, Koji Inagaki, Takayuki Yamaguchi, Takahiro Hata, Naoki Miyagawa, Yoshihiro Kitagawa
Publikováno v:
Biologicalpharmaceutical bulletin. 43(2)
Colony stimulating factor 1 (CSF1) receptor (CSF1R) is a receptor protein-tyrosine kinase specifically expressed in monocyte-lineage cells, such as monocytes and macrophages. In this study, we characterized the pharmacological properties of an azetid
Autor:
Fukuda Kenji, Shuichi Kimura, Takashi Nakagawa, Toshihiro Kiguchi, Hiromasa Hashimoto, Yushi Matsuo, Kazuhito Harada, Mariko Maekawa, Soejima Yuki, Masanori Shindo, Masaki Takagi, Mikio Hayashi, Naoki Ogawa, Kazuyuki Hirata, Taku Ikenogami, Yuko Shinagawa, Takeo Katsushima, Mitsuru Takahashi, Teruhiko Inoue
Publikováno v:
ACS Medicinal Chemistry Letters. 2:238-242
Short-acting oral calcilytics, calcium-sensing receptor (CaSR) antagonists, have been considered as alternatives for parathyroid hormone (PTH), an injectable bone anabolic drug used in the treatment of osteoporosis. Previously, we identified aminopro
Autor:
Masanori Shindo, Kazuyuki Hirata, Yuko Shinagawa, Teruhiko Inoue, Yushi Matsuo, Takeo Katsushima, Takashi Nakagawa, Hiromasa Hashimoto
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3809-3813
Synthesis and structure-activity relationship studies on a new aminopropandiol class of derivatives as calcium-sensing receptor antagonists are described. Modification of the phenolic moiety of a calcilytic compound NPS 2143 led to the identification
Autor:
Akiko Takimoto, Sawako Suzuki, Fumiaki Maruo, Yushi Matsuo, Michiyoshi Kobayashi, Hirofumi Shoun
Publikováno v:
Journal of Biological Chemistry. 271:16263-16267
Subcellular localization and coupling to ATP synthesis were investigated with respect to the denitrifying systems of two fungi, Fusarium oxysporum and Cylindrocarpon tonkinense. Dissimilatory nitrate reductase of F. oxysporum or nitrite reductase of
Autor:
Mikio Hayashi, Yuji Ishida, Takashi Nakagawa, Yoshihisa Okamoto, Yushi Matsuo, Shuichi Kimura
Publikováno v:
European journal of pharmacology. 668(1-2)
Intermittent administration of parathyroid hormone (PTH) has a potent anabolic effect on bone in humans and animals. Calcium-sensing receptor (CaSR) antagonists stimulate endogenous PTH secretion through CaSR on the surface of parathyroid cells and t
Autor:
Yushi Matsuo, Hiroshi Hamamatsu
Publikováno v:
The Proceedings of Conference of Kyushu Branch. :125-126
Publikováno v:
Physical Chemistry Chemical Physics. 14:14049
The location, orientation, and dynamics of hydrophobic small molecules in lipid membranes are studied through combined use of solution-state (1)H-NMR and MD simulation. 1-Naphthol and 1-methylnaphthalene were adopted as the small molecules with or wi
Publikováno v:
Bioscience, biotechnology, and biochemistry. 56(10)
Erwinia carotovora Er produces three extra-cellular pectate lyases (PL I, II, and III). The gene for pectate lyase II (pelII) of E. carotovora Er was cloned and expressed both in Escherichia coli and E. carotovora Er. Localization experiments in E. c