Retinal Nerve Fiber Layer Thickness Progression after Robotic-Assisted Laparoscopic Radical Prostatectomy in Glaucoma Patients

Autor: Kazuyuki Hirooka, Kaori Ukegawa, Eri Nitta, Nobufumi Ueda, Yushi Hayashida, Hiromi Hirama, Rikiya Taoka, Yuma Sakura, Mari Yamasaki, Hiroyuki Tsunemori, Mikio Sugimoto, Yoshiaki Kiuchi

Publikováno v: Journal of Ophthalmology, Vol 2019 (2019)

Purpose. To investigate the effect of the steep Trendelenburg position surgical procedure on the retinal structure and function during robotic-assisted laparoscopic radical prostatectomy (RALP) in glaucoma patients. Methods. At 1 month and 1 day befo

Externí odkaz: https://doaj.org/article/7088203151124198b1d00100b9adfb09

Real-world analysis of apalutamide-associated skin adverse events in Japanese patients with advanced prostate cancer: a multi-institutional study in the Chu-shikoku Japan Urological Consortium

Autor: Yoichiro, Tohi, Takuma, Kato, Hideo, Fukuhara, Keita, Kobayashi, Shin, Ohira, Kenichiro, Ikeda, Kei, Daizumoto, Satoshi, Katayama, Ryutaro, Shimizu, Kenichi, Nishimura, Taichi, Nagami, Yushi, Hayashida, Hiromi, Hirama, Atsushi, Takamoto, Teruki, Dainichi, Mikio, Sugimoto

Publikováno v: International journal of clinical oncology. 27(8)

Apalutamide-associated skin adverse events are more common in the Japanese than in the global population. However, limited clinical data have hampered further understanding. This real-world study investigated the clinical characteristics of skin adve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6443342c693dab253a9c1b5c7ca63783
https://pubmed.ncbi.nlm.nih.gov/35596089

Invention of a novel photodynamic therapy for tumors using a photosensitizing PI3K inhibitor

Autor: Nobukazu Araki, Katsuhisa Kawai, Takuma Kato, Koichi Sawada, Yoshiyuki Kakehi, Yuka Ikeda, Yushi Hayashida

Publikováno v: International Journal of Cancer. 139:700-711

XL147 (SAR245408, pilaralisib), an ATP-competitive pan-class I phosphoinositide 3-kinase (PI3K) inhibitor, is a promising new anticancer drug. We examined the effect of the PI3K inhibitor on PC3 prostate cancer cells under a fluorescence microscope a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b69ae69badc61273db8474132de4745e
https://doi.org/10.1002/ijc.30097

G Protein-Coupled Receptor 87 (GPR87) Promotes Cell Proliferation in Human Bladder Cancer Cells

Autor: Takeshi Hashimoto, Mikio Sugimoto, Dage Liu, Xia-Xia Zhang, Homare Okazoe, Nobufumi Ueda, Yoshiyuki Kakehi, Yushi Hayashida

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 16, Iss 10, Pp 24319-24331 (2015)
Volume 16
Issue 10
Pages 24319-24331

G protein-coupled receptor 87 (GPR87) is a newly deorphanized member of the cell surface molecule G protein-coupled receptor family. GPR signaling was shown to play a role in promotion of cell growth and survival, metastasis, and drug resistance. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b978a6f7780a740a1ed873dd56b7da61
http://europepmc.org/articles/PMC4632752

Induction of G2/M arrest and apoptosis through mitochondria pathway by a dimer sesquiterpene lactone from Smallanthus sonchifolius in HeLa cells

Autor: Yushi Hayashida, Xia Zhang, Yoshiyuki Kakehi, Yurika Kitai, Hirotoshi Tamura

Publikováno v: Journal of Food and Drug Analysis, Vol 25, Iss 3, Pp 619-627 (2017)

Dimer sesquiterpene lactones (SLs), uvedafolin and enhydrofolin, against four monomer SLs isolated from yacon, Smallanthus sonchifolius , leaf were the most cytotoxic substances on HeLa cells (IC 50 values 2.96–3.17 μM at 24 hours). However, the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be7c13379d276d6eb40419bed2bf658