Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yushan Xia"'
Autor:
Chenyuan Wang, Yushan Xia, Runming Wang, Jingru Li, Chun-Lung Chan, Richard Yi-Tsun Kao, Patrick H. Toy, Pak-Leung Ho, Hongyan Li, Hongzhe Sun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The rapid emergence of antimicrobial resistance (AMR) pathogens highlights the urgent need to approach this global burden with alternative strategies. Cefiderocol (Fetroja®) is a clinically-used sideromycin, that is utilized for the treatme
Externí odkaz:
https://doaj.org/article/c1898164917c40cdbcd6259a2256dd7e
Autor:
Guangrong Lu, Jiajia Li, Yejiao Ruan, Yuning Shi, Xuchao Zhang, Yushan Xia, Zheng Zhu, Jiafeng Lin, Lili Li
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Age is an independent prognostic factor for small cell lung cancer (SCLC). We aimed to construct a nomogram survival prediction for elderly SCLC patients based on the Surveillance, Epidemiology, and End Results (SEER) database. Me
Externí odkaz:
https://doaj.org/article/9c5d63d9bc9a4ccfb5cd01223fff4835
Autor:
Hao Chen, Xuetao Gong, Zheng Fan, Yushan Xia, Yongxin Jin, Fang Bai, Zhihui Cheng, Xiaolei Pan, Weihui Wu
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Carbohydrate metabolism plays essential roles in energy generation and providing carbon skeletons for amino acid syntheses. In addition, carbohydrate metabolism has been shown to influence bacterial susceptibility to antibiotics and virulenc
Externí odkaz:
https://doaj.org/article/fa48060666954f9fb35c0c329a4b29aa
Autor:
Dan Wang, Xinxin Zhang, Liwen Yin, Qi Liu, Zhaoli Yu, Congjuan Xu, Zhenzhen Ma, Yushan Xia, Jing Shi, Yuehua Gong, Fang Bai, Zhihui Cheng, Weihui Wu, Jinzhong Lin, Yongxin Jin
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1 (2022)
Pseudomonas aeruginosa is an important opportunistic pathogen capable of causing variety of infections in humans. The type III secretion system (T3SS) is a critical virulence determinant of P. aeruginosa in the host infections. Expression of the T3SS
Externí odkaz:
https://doaj.org/article/9f5a5b7b1dec4160bfec69cc82666144
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009909 (2021)
The emergence and rapid spread of multi-drug resistant (MDR) bacteria pose a serious threat to the global healthcare. There is an urgent need for new antibacterial substances or new treatment strategies to deal with the infections by MDR bacterial pa
Externí odkaz:
https://doaj.org/article/dad67f8297b1411196e95ff6b8347791
Autor:
Haozhou Li, Yushan Xia, Zhenyang Tian, Yongxin Jin, Fang Bai, Zhihui Cheng, Wieslaw Swietnicki, Weihui Wu, Xiaolei Pan
Publikováno v:
Microorganisms, Vol 10, Iss 3, p 666 (2022)
Carbon metabolism plays an important role in bacterial physiology and pathogenesis. The type III secretion system (T3SS) of Pseudomonas aeruginosa is a virulence factor that contributes to acute infections. It has been demonstrated that bacterial met
Externí odkaz:
https://doaj.org/article/24fb1fb988dd436f8f21eba7fa8bd713
Autor:
Yushan Xia, Yuding Weng, Congjuan Xu, Dan Wang, Xiaolei Pan, Zhenyang Tian, Bin Xia, Haozhou Li, Ronghao Chen, Chang Liu, Yongxin Jin, Fang Bai, Zhihui Cheng, Oscar P. Kuipers, Weihui Wu
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Posttranscriptional regulation plays an essential role in the quick adaptation of pathogenic bacteria to host environments, and RNases play key roles in this process by modifying small RNAs and mRNAs. We find that the Pseudomonas aeruginosa
Externí odkaz:
https://doaj.org/article/a20a993afdc2485cbe06b3e3837ce7c1
Autor:
Yushan Xia, Dan Wang, Xiaolei Pan, Bin Xia, Yuding Weng, Yuqing Long, Huan Ren, Jingyi Zhou, Yongxin Jin, Fang Bai, Zhihui Cheng, Shouguang Jin, Weihui Wu
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Carbon metabolism plays an essential role in bacterial pathogenesis and susceptibility to antibiotics. In Pseudomonas aeruginosa, Crc, Hfq, and a small RNA, CrcZ, are central regulators of carbon metabolism. By screening mutants of genes inv
Externí odkaz:
https://doaj.org/article/cbf728bb86554fda9f6bb29830423dfc
Autor:
Xiangxiang Wang, Yushan Xia, Yongxin Jin, Xueying Wei, Zhenpeng Li, Zhihui Cheng, Fang Bai, Yuding Weng, Shouguang Jin, WenRan Ren, Ronghao Chen, Weihui Wu
Publikováno v:
Environmental Microbiology. 21:2933-2947
The biofilm formation by Pseudomonas aeruginosa highly increases the bacterial resistance to antimicrobial agents and host immune clearance. The biofilm formation is positively regulated by two small RNAs, RsmY and RsmZ. Previously, we reported that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f835cceb0a1cd83fa347ef3651886f
https://doi.org/10.1111/1462-2920.14686
https://doi.org/10.1111/1462-2920.14686
Autor:
Huan Ren, Fang Bai, Yongxin Jin, Jianfeng Liu, Shouguang Jin, Zheng Fan, Weixin Fu, Mei Li, Chang Liu, Yuqing Long, Chang Xu, Zhihui Cheng, Shouyi Li, Xiaoyun Liu, Buyu Zhang, Yushan Xia, Weihui Wu
Publikováno v:
Journal of Antimicrobial Chemotherapy. 74:2575-2587
ObjectivesBacterial persisters are a small subpopulation of cells that are highly tolerant of antibiotics and contribute to chronic and recalcitrant infections. Global gene expression in Pseudomonas aeruginosa persister cells and genes contributing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6610ae8fdd1f2f96c2aa78d075d68fb3
https://doi.org/10.1093/jac/dkz214
https://doi.org/10.1093/jac/dkz214