Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yusha Ru"'
Autor:
Ying Lv, Chenchen Chu, Ke Liu, Yusha Ru, Yan Zhang, Xiaoxiao Lu, Yichen Gao, Caijie Zhang, Shaozhen Zhao
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract An important mechanism involved in dry eye (DE) is the association between tear hyperosmolarity and inflammation severity. Inflammation in DE might be mediated by the NLRP3 inflammasome, which activated by exposure to reactive oxygen species
Externí odkaz:
https://doaj.org/article/c983e81ba80f48bb9797811f0055dcc3
Autor:
Xiaoxiao Lu, Abirami Kugadas, Kirsten Smith-Page, Jeffrey Lamb, Tiffany Lin, Yusha Ru, Sharon Celeste Morley, Raina Fichorova, Sharad K. Mittal, Sunil K. Chauhan, Sejiro Littleton, Daniel Saban, Mihaela Gadjeva
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Why ocular mucosa is paucibacterial is unknown. Many different mechanisms have been suggested but the comprehensive experimental studies are sparse. We found that a deficiency in L-plastin (LCP1), an actin bundling protein, resulted in an ocular comm
Externí odkaz:
https://doaj.org/article/aec72e9a91194cf59bd2689b12f81611
Autor:
Siwei Cai, Qianhui Yang, Mengzhu Hou, Qian Han, Hanyu Zhang, Jiantao Wang, Chen Qi, Qiyu Bo, Yusha Ru, Wei Yang, Zhongxiu Gu, Ruihua Wei, Yunshan Cao, Xiaorong Li, Yan Zhang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 2, Pp 505-522 (2018)
Background/Aims: Blood-retinal barrier (BRB) breakdown and vascular leakage is the leading cause of blindness of diabetic retinopathy (DR). Hyperglycemia-induced oxidative stress and inflammation are primary pathogenic factors of this severe DR compl
Externí odkaz:
https://doaj.org/article/698faa25117945578551a7a3d8531581
Autor:
Yusha Ru, Yue Huang, Shaozhen Zhao, Xiaoxiao Lu, Yan Zhang, Zhe Jia, Chenchen Chu, Ying Lv, Yichen Gao
Publikováno v:
Theranostics
Rationale: Corneal transplantation is an effective treatment to corneal blindness. However, the immune rejection imperils corneal allograft survival. An interventional modality is urgently needed to inhibit immune rejection and promote allograft surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95eb02a55d3298f0e4731ceeedd8ef5
https://doi.org/10.7150/thno.31711
https://doi.org/10.7150/thno.31711
Autor:
Ke Liu, Lu Gan, Chenchen Chu, Yue Huang, Yan Zhang, Yusha Ru, Xiaoyu Zeng, Xiaoxiao Lu, Shaozhen Zhao
Publikováno v:
Experimental eye research. 210
Dry eye (DE) is a chronic, multifactorial ocular surface disease associated with visual disturbance, tear film instability, hyperosmolarity, ocular surface inflammation and damage. Effective intervention is necessary to control this disease. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066ab3bc1bf63e1f5ccc93372f258a3b
https://pubmed.ncbi.nlm.nih.gov/34252414
https://pubmed.ncbi.nlm.nih.gov/34252414
Autor:
Sharad K. Mittal, Raina N. Fichorova, Sharon Celeste Morley, Daniel R. Saban, Abirami Kugadas, Tiffany Lin, Mihaela Gadjeva, Jeffrey Lamb, Sejiro Littleton, Xiaoxiao Lu, Kirsten Smith-Page, Sunil K. Chauhan, Yusha Ru
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Why ocular mucosa is paucibacterial is unknown. Many different mechanisms have been suggested but the comprehensive experimental studies are sparse. We found that a deficiency in L-plastin (LCP1), an actin bundling protein, resulted in an ocular comm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d909d5200d336554d0706c26bc6dec
https://doi.org/10.3389/fimmu.2020.00547
https://doi.org/10.3389/fimmu.2020.00547
Autor:
Qianhui Yang, Mengzhu Hou, Xiaorong Li, Yan Zhang, Qian Han, Siwei Cai, Yunshan Cao, Ruihua Wei, Qiyu Bo, Chen Qi, Yusha Ru, Wei Yang, Zhongxiu Gu, Hanyu Zhang, Jiantao Wang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 2, Pp 505-522 (2018)
Background/Aims: Blood-retinal barrier (BRB) breakdown and vascular leakage is the leading cause of blindness of diabetic retinopathy (DR). Hyperglycemia-induced oxidative stress and inflammation are primary pathogenic factors of this severe DR compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61736f13e8850eae6778de1265de093b
https://www.karger.com/Article/FullText/487029
https://www.karger.com/Article/FullText/487029
Autor:
Yan Zhang, Qian Han, Jing Jiang, Xun Liu, Xiaomin Zhang, Mianmian Wu, Jianmin Fang, Ling Wang, Qiyu Bo, Qianhui Yang, Guangwei Yu, Yusha Ru, Min Huang, Xiaorong Li
Publikováno v:
International Journal of Ophthalmology, Vol 11, Iss 6, Pp 935-944 (2018)
AIM: To investigate protective effects of a novel recombinant decoy receptor drug RC28-E on retinal damage in early diabetic rats. METHODS: The streptozotocin (STZ)-induced diabetic rats were randomly divided into 6 groups: diabetes mellitus (DM) gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb634aa098d4ec16bb7a53a267bb1a20
https://pubmed.ncbi.nlm.nih.gov/29977804
https://pubmed.ncbi.nlm.nih.gov/29977804
Autor:
Xun Liu, Yue Huang, Juan Du, Zhu Meng, Huijuan Liu, Rui Hua Wei, Yan Zhang, Zexia Dou, Shaozhen Zhao, Yusha Ru
Publikováno v:
Scientific Reports
Dry eye is a highly prevalent, chronic and multifactorial disease that compromises quality of life and generates socioeconomic burdens. The pathogenic factors of dry eye disease (DED) include tear secretion abnormalities, tear film instability and oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15449813f2f86b484e94bcec73871eab
http://europepmc.org/articles/PMC4685655
http://europepmc.org/articles/PMC4685655
Autor:
Xiaomin Zhang, Weihui Wu, Xun Liu, Shan Ma, Yan Zhang, Qian Han, Yusha Ru, Chang Xu, Qianhui Yang, Guangwei Yu, Qiyu Bo, Rui Hua Wei, Fei E. Wang, Yunshan Cao, Xiaorong Li
Publikováno v:
Scientific Reports
Glutamate excitotoxicity is a common pathology to blinding ischemic retinopathies, such as diabetic retinopathy, glaucoma and central retinal vein or artery occlusion. The development of an effective interventional modality to glutamate excitotoxicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49bd33a1ce88c0bd597790f9c918c6da
https://doi.org/10.1038/srep15812
https://doi.org/10.1038/srep15812