Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Yusaku Mori"'
Autor:
Tsutomu Hirano, Toshiyuki Hayashi, Hiroe Sugita, Atsuko Tamasawa, Satoshi Goto, Masako Tomoyasu, Takeshi Yamamoto, Makoto Ohara, Michishige Terasaki, Hideki Kushima, Yasuki Ito, Sho‐ichi Yamagishi, Yusaku Mori
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 12, Pp 1401-1411 (2023)
Abstract Aims/Introduction Small dense low‐density lipoprotein (sdLDL) is a more potent atherogenic lipoprotein than LDL. As sdLDL‐cholesterol (C) levels are determined by triglyceride and LDL‐C levels, pemafibrate and statins can reduce sdLDL
Externí odkaz:
https://doaj.org/article/7b723e31cf984844b51b51d4814f39f0
Autor:
Michishige Terasaki, Hironori Yashima, Yusaku Mori, Tomomi Saito, Naoto Inoue, Takanori Matsui, Naoya Osaka, Tomoki Fujikawa, Makoto Ohara, Sho-ichi Yamagishi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9724 (2024)
Glucose-dependent insulinotropic polypeptide (GIP) of the incretin group has been shown to exert pleiotropic actions. There is growing evidence that advanced glycation end products (AGEs), senescent macromolecules formed at an accelerated rate under
Externí odkaz:
https://doaj.org/article/1382ef28b30e447390273eed3854eaf1
Autor:
Yusaku Mori, Michishige Terasaki, Naoya Osaka, Tomoki Fujikawa, Hironori Yashima, Tomomi Saito, Yurie Kataoka, Makoto Ohara, Yuichiro Higashimoto, Takanori Matsui, Sho-ichi Yamagishi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5947 (2024)
Type 2 diabetes mellitus (T2DM) is a risk factor for male infertility, but the underlying molecular mechanisms remain unclear. Advanced glycation end products (AGEs) are pathogenic molecules for diabetic vascular complications. Here, we investigated
Externí odkaz:
https://doaj.org/article/e3d217edffaf46f494c5f1b073fc8465
Autor:
Nobuaki Takehana, Tomoyasu Fukui, Yusaku Mori, Munenori Hiromura, Michishige Terasaki, Makoto Ohara, Michiya Takada, Masako Tomoyasu, Yoshihisa Ito, Tetsuro Kobayashi, Sho‐ichi Yamagishi
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 7, Pp 856-863 (2023)
Abstract Aims/Introduction This study aimed to compare the positivity rates of glutamic acid decarboxylase autoantibodies (GADA) and ElisaRSR™ 3 Screen ICA™ (3 Screen ICA), a newly developed assay for the simultaneous measurement of GADA, insulin
Externí odkaz:
https://doaj.org/article/ccf155f05aba41eeaa310a9ea7bbecf1
Autor:
Yusaku Mori, Makoto Ohara, Michishige Terasaki, Naoya Osaka, Hironori Yashima, Tomomi Saito, Yurie Otoyama-Kataoka, Takemasa Omachi, Yuichiro Higashimoto, Takanori Matsui, Tomoyasu Fukui, Sho-ichi Yamagishi
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3112 (2023)
We have developed DNA aptamers that can inhibit the toxic effects of advanced glycation end products (AGE-Apts). We herein evaluated the effects of AGE-Apts on muscle mass and strength in senescence-accelerated mouse prone 8 (SAMP8) mice. Eight-month
Externí odkaz:
https://doaj.org/article/2702c5b64a744305b3a937b78da3457c
Autor:
Naoya Osaka, Yusaku Mori, Michishige Terasaki, Munenori Hiromura, Tomomi Saito, Hironori Yashima, Yoshie Shiraga, Raichi Kawakami, Makoto Ohara, Tomoyasu Fukui, Sho-ichi Yamagishi
Publikováno v:
Journal of International Medical Research, Vol 50 (2022)
Objective Sodium-glucose cotransporter-2 (SGLT2) inhibitors exhibit cardioprotective properties in patients with diabetes. However, SGLT2 is not expressed in the heart, and the underlying molecular mechanisms are not fully understood. We investigated
Externí odkaz:
https://doaj.org/article/70384bedcd3a41af9453288197520c36
Autor:
Michishige Terasaki, Keita Shibata, Yusaku Mori, Tomomi Saito, Takanori Matsui, Makoto Ohara, Tomoyasu Fukui, Keiji Hasumi, Yuichiro Higashimoto, Koji Nobe, Sho-ichi Yamagishi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6505 (2023)
SMTP-44D has been reported to have anti-oxidative and anti-inflammatory reactions, including reduced expression of receptor for advanced glycation end products (RAGE) in experimental diabetic neuropathy. Although activation of RAGE with its ligands,
Externí odkaz:
https://doaj.org/article/b8b500fe2ff340e1a7a187afd4018736
Autor:
Ayako Fukase, Tomoyasu Fukui, Hiroto Sasamori, Munenori Hiromura, Michishige Terasaki, Yusaku Mori, Toshiyuki Hayashi, Takeshi Yamamoto, Makoto Ohara, Satoshi Goto, Hiroe Nagaike, Tsutomu Hirano, Sho‐ichi Yamagishi
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 5, Pp 1188-1196 (2020)
Abstract Aims To clarify the clinical impact of pancreatic fat volume on beta cell function in type 2 diabetes patients. Materials and Methods One hundred thirty two consecutive type 2 diabetic patients (mean age, 63.7 years) were enrolled in this cr
Externí odkaz:
https://doaj.org/article/16d5dea8472c47619dd4ffbde3de9f32
Autor:
So Yamamura, Tomoyasu Fukui, Yusaku Mori, Toshiyuki Hayashi, Takeshi Yamamoto, Makoto Ohara, Ayako Fukase, Hiroto Sasamori, Tetsuro Kobayashi, Tsutomu Hirano
Publikováno v:
Journal of Diabetes Investigation, Vol 10, Iss 6, Pp 1480-1489 (2019)
Abstract Aims/Introduction To elucidate the relationship between titers of islet autoantibodies, the C‐X‐C motif chemokine 10 – a circulating chemokine that activates T‐helper 1 cells leading to β‐cell destruction – and β‐cell functio
Externí odkaz:
https://doaj.org/article/5a8032e6b9f841039c9e26bc8117b1cb
Autor:
Yusaku Mori, Michishige Terasaki, Munenori Hiromura, Tomomi Saito, Hideki Kushima, Masakazu Koshibu, Naoya Osaka, Makoto Ohara, Tomoyasu Fukui, Hirokazu Ohtaki, Hirano Tsutomu, Sho-ichi Yamagishi
Publikováno v:
Cardiovascular Diabetology, Vol 18, Iss 1, Pp 1-9 (2019)
Abstract Background Excess fat deposition could induce phenotypic changes of perivascular adipose tissue (PVAT remodeling), which may promote the progression of atherosclerosis via modulation of adipocytokine secretion. However, it remains unclear wh
Externí odkaz:
https://doaj.org/article/34d39adfe63b4b768cdb679bcb87eac5