Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Yury G. Kaminsky"'
Autor:
Elena A. Kosenko, Lyudmila A. Tikhonova, Carmina Montoliu, George E. Barreto, Gjumrakch Aliev, Yury G. Kaminsky
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2018)
Alzheimer's disease (AD) is a slowly progressive, neurodegenerative disorder of uncertain etiology. According to the amyloid cascade hypothesis, accumulation of non-soluble amyloid β peptides (Aβ) in the Central Nervous System (CNS) is the primary
Externí odkaz:
https://doaj.org/article/247ab36219b84ad7abe0f17519f4b913
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 15:113-123
Alzheimer disease (AD) is one of the most common neurodegenerative disorders widely occurring among the elderly. The pathogenic mechanisms involved in the development of this disease are still unknown. In AD, in addition to brain, a number of periphe
Autor:
Elena Kosenko, Carmina Montoliu, Gubidat Alilova, Lyudmila A. Tikhonova, Yury G. Kaminsky, George E. Barreto, Gjumrakch Aliev
Publikováno v:
Free radical biologymedicine. 113
The portacaval shunting (PCS) prevents portal hypertension and recurrent bleeding of esophageal varices. On the other hand, it can induce chronic hyperammonemia and is considered to be the best model of mild hepatic encephalopathy (HE). Pathogenic me
Autor:
Iliya N. Solomadin, Lyudmila A. Tikhonova, Yury G. Kaminsky, Gjumrakch Aliev, Yi Li, Elena Kosenko, Prakash Reddy
Publikováno v:
American Journal of Alzheimer's Disease & Other Dementiasr. 29:685-695
Amyloid β25-35 (Aβ25-35) represents a neurotoxic fragment of Aβ1-40 or Aβ1-42, and is implicated in the progressive neurodegeneration in cases of the Alzheimer disease (AD). Amyloid β25-35 was shown to lyse rat erythrocytes (RBCs) of all ages, a
Autor:
G. Md Ashraf, Yury G. Kaminsky, Valery V. Benberin, Ramón Cacabelos, Vladimir N. Nikolenko, Andrey A. Zamyatnin, Medha Priyadarshini, Gjumrakch Aliev, Mohammad Amjad Kamal, V. P. Reddy, Nigel H. Grieg, Sergey O. Bachurin, Nasimudeen R. Jabir
Publikováno v:
Current Medicinal Chemistry. 21:2208-2217
Mitochondrial dysfunction plausibly underlies the aging-associated brain degeneration. Mitochondria play a pivotal role in cellular bioenergetics and cell-survival. Oxidative stress consequent to chronic hypoperfusion induces mitochondrial damage, wh
Autor:
Lyudmila A. Tikhonova, Yury G. Kaminsky, Elena Kosenko, Gjumrakch Aliev, Iliya N. Solomadin, V. Prakash Reddy
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 13:112-119
Aβ exerts prooxidant or antioxidant effects based on the metal ion concentrations that it sequesters from the cytosol; at low metal ion concentrations, it is an antioxidant, whereas at relatively higher concentration it is a prooxidant. Thus Alzheim
Publikováno v:
Biomeditsinskaya Khimiya. 59:443-451
Age of patients and brain oxidative stress may contribute to pathogenesis of Alzheimer's disease (AD). Erythrocytes (red blood cells, RBC) are considered as passive “reporter cells” for the oxidative status of the whole organism and are not well
Autor:
Andrey A. Zamyatnin, Vladimir N. Nikolenko, Gjumrakch Aliev, Yury G. Kaminsky, Yi Li, Sergey O. Bachurin, N. N. Yakhno, Arturo Solís-Herrera, Valery V. Benberin
Publikováno v:
Open Journal of Psychiatry. :408-421
Kleiber’s Law or E = M3/4 is a mathematical expression known since 1932 that outlines the relationship between mass (biomass) and the use of energy. It is compelling because it supports a long standing observation that larger animals appear to use
Publikováno v:
Cardiovascularhematological agents in medicinal chemistry. 14(1)
This study investigated the effect of antihypertensive therapy with lisinopril on plasma cholesterol concentration and erythrocyte catalase activity in hypertensive patients. We observed, for the first time, significant inverse correlations between s
Autor:
Elena Kosenko, Mohammad Amjad Kamal, Armenuhi Poghosyan, Lyudmila A. Tikhonova, Yury G. Kaminsky, Gjumrakch Aliev, Hector H. Palacios
Publikováno v:
American Journal of Neuroprotection and Neuroregeneration. 4:73-77
Background: Accumulating evidence implicates a role for altered energy and proteolytic metabolism in the pathogenesis of Alzheimer disease (AD), but the involvement of erythrocytes (RBC) remains to be completely understood. The objective stands to te