Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yury D Bogdanov"'
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251632 (2021)
BackgroundThe major sites for fast synaptic inhibition in the central nervous system (CNS) are ion channels activated by γ-aminobutyric acid (GABA). These receptors are referred as GABA(A) receptors (GABA(A)R). Recent evidence indicates a role of GA
Externí odkaz:
https://doaj.org/article/9ada402162ab4f38b756f30cc092c1e3
Autor:
Michael S. Minett, Sarah Falk, Sonia Santana-Varela, Yury D. Bogdanov, Mohammed A. Nassar, Anne-Marie Heegaard, John N. Wood
Publikováno v:
Cell Reports, Vol 6, Iss 2, Pp 301-312 (2014)
Nav1.7, a peripheral neuron voltage-gated sodium channel, is essential for pain and olfaction in mice and humans. We examined the role of Nav1.7 as well as Nav1.3, Nav1.8, and Nav1.9 in different mouse models of chronic pain. Constriction-injury-depe
Externí odkaz:
https://doaj.org/article/7573c1aad53d411887931726ea7c84fb
Autor:
Alexander P. Simpson, Ali Roghanian, Robert J. Oldham, H.T. Claude Chan, Christine A. Penfold, Hyung J. Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Kerry L. Cox, Yury D. Bogdanov, Sonya James, Alison L. Tutt, Daniel Rycroft, Peter Morley, Lekh N. Dahal, Ingrid Teige, Björn Frendeus, Stephen A. Beers, Mark S. Cragg
Publikováno v:
Cell Reports. 40:111099
Many therapeutic antibodies deplete target cells and elicit immunotherapy by engaging activating Fc gamma receptors (FcγRs) on host effector cells. These antibodies are negatively regulated by the inhibitory FcγRIIB (CD32B). Dogma suggests inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fcf664863a09dd4ef06c7394380d5c
https://doi.org/10.1016/j.celrep.2022.111099
https://doi.org/10.1016/j.celrep.2022.111099
Autor:
Stephen A. Beers, Yury D. Bogdanov, Khiyam Hussain, Sonya James, Mark S. Cragg, Emma L Sparrow
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0251632 (2021)
PLoS ONE, Vol 16, Iss 5, p e0251632 (2021)
Background The major sites for fast synaptic inhibition in the central nervous system (CNS) are ion channels activated by γ-aminobutyric acid (GABA). These receptors are referred as GABA(A) receptors (GABA(A)R). Recent evidence indicates a role of G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6903de3f9f080d0b693080fbb89c50f6
https://eprints.soton.ac.uk/449625/
https://eprints.soton.ac.uk/449625/
Autor:
Jane E. Sexton, Yury D. Bogdanov, Samuel J. Gossage, Shengnan Li, Andrei L. Okorokov, Larissa de Clauser, Federico Iseppon, Ana P. Luiz, Jing Zhao, John N. Wood, Sonia Santana-Varela, James J. Cox, Marta Alves-Simoes
Publikováno v:
Wellcome Open Research. 6:250
Background: Somatosensation depends on primary sensory neurons of the trigeminal and dorsal root ganglia (DRG). Transcriptional profiling of mouse DRG sensory neurons has defined at least 18 distinct neuronal cell types. Using an advillin promoter, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bea00123b8e721965d67ec7344940ec
https://doi.org/10.12688/wellcomeopenres.17090.1
https://doi.org/10.12688/wellcomeopenres.17090.1
Autor:
Lina Happo, Andreas Strasser, Matthew J. Carter, Stuart Blakemore, Graham Packham, Mark S. Cragg, Yury D. Bogdanov, Clare L. Scott, Kerry L. Cox
Publikováno v:
Cell Death & Differentiation. 23:303-312
Genetic recombination during B-cell development regularly results in the generation of autoreactive, potentially pathogenic B-cell receptors (BCRs). Consequently, multiple mechanisms link inappropriate BCR specificity to clonal deletion. Similar path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b97c389b808ef1493ae9b028531580
https://doi.org/10.1038/cdd.2015.97
https://doi.org/10.1038/cdd.2015.97
Autor:
Fan Wang, John N. Wood, Joanne Lau, Yury D. Bogdanov, Michael S. Minett, Jing Zhao, Ulla Dennehy
Publikováno v:
Molecular Pain
Molecular Pain, Vol 7, Iss 1, p 100 (2011)
Molecular Pain, Vol 7, Iss 1, p 100 (2011)
Background: Tissue-specific gene deletion has proved informative in the analysis of pain pathways. Advillin has been shown to be a pan-neuronal marker of spinal and cranial sensory ganglia. We generated BAC transgenic mice using the Advillin promoter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9b6188bc7ce574acb824cf01437647
https://doi.org/10.1186/1744-8069-7-100
https://doi.org/10.1186/1744-8069-7-100
Autor:
Guido Michels, Jon Lindstrom, Yury D. Bogdanov, Menelas N. Pangalos, Stephen J. Moss, Cecilia E. Armstrong-Gold, Philip G. Haydon
Publikováno v:
The EMBO Journal. 25:4381-4389
GABAA receptors mediate the majority of fast synaptic inhibition in the brain. The accumulation of these ligand-gated ion channels at synaptic sites is a prerequisite for neuronal inhibition, but the molecular mechanisms underlying this phenomenon re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee54571f1487120b0644bf3d00febd6
https://doi.org/10.1038/sj.emboj.7601309
https://doi.org/10.1038/sj.emboj.7601309
Autor:
Kristina McAinsh, Josef T. Kittler, Volker Haucke, Guojun Chen, Stephen J. Moss, Yury D. Bogdanov, Stephan Honing, Jasmina N. Jovanovic, I. Lorena Arancibia-Carcamo, Zhen Yan, Menelas N. Pangalos
Publikováno v:
Proceedings of the National Academy of Sciences. 102:14871-14876
The efficacy of synaptic inhibition depends on the number of γ-aminobutyric acid type A receptors (GABA A Rs) expressed on the cell surface of neurons. The clathrin adaptor protein 2 (AP2) complex is a critical regulator of GABA A R endocytosis and,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1903689f739a77a167394355d84a39
https://doi.org/10.1073/pnas.0506653102
https://doi.org/10.1073/pnas.0506653102
Autor:
Yury D. Bogdanov, Annette C. Dolphin, Karen M. Page, C Canti, S. G. Volsen, M. Li, N. L. Brice
Publikováno v:
European Journal of Neuroscience. 12:894-902
Voltage-dependent calcium channels consist of a pore-forming transmembrane alpha 1-subunit, which is known to associate with a number of accessory subunits, including alpha 2-delta- and beta-subunits. The beta-subunits, of which four have been identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e3b11a6e11e2f46498519fb36ded4eb
https://doi.org/10.1046/j.1460-9568.2000.00981.x
https://doi.org/10.1046/j.1460-9568.2000.00981.x