Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Yury A, Portnoy"'
Autor:
Alla V. Filimonova, Maria V. Golikova, Elena N. Strukova, Yury A. Portnoy, Anastasiya A. Kuznetsova, Stephen H. Zinner
Publikováno v:
Antibiotics, Vol 10, Iss 12, p 1520 (2021)
Traditionally, the antibacterial activity of β-lactam antibiotics in the presence of β-lactamase inhibitors is determined at the fixed inhibitor concentration. This traditional approach does not consider the ratio of antibiotic-to-inhibitor concent
Externí odkaz:
https://doaj.org/article/0351b8d6e87049bca282a5be0d0ccc02
Autor:
Maria V. Golikova, Elena N. Strukova, Yury A. Portnoy, Stephen H. Zinner, Alexander A. Firsov
Publikováno v:
Antibiotics, Vol 10, Iss 10, p 1148 (2021)
To explore whether combined treatments with daptomycin and gentamicin can prevent the development of Staphylococcus aureus resistance, and whether the possible restriction is associated with changes in antibiotic mutant prevention concentrations (MPC
Externí odkaz:
https://doaj.org/article/8cde7af0099b4a75a84e1c1012db1140
Autor:
Maria V. Golikova, Elena N. Strukova, Yury A. Portnoy, Stephen H. Zinner, Alexander A. Firsov
Publikováno v:
Antibiotics, Vol 9, Iss 9, p 538 (2020)
To explore whether susceptibility testing with antibiotic combinations at pharmacokinetically derived concentration ratios is predictive of the antimicrobial effect, a Staphylococcus aureus strain was exposed to daptomycin and gentamicin alone or in
Externí odkaz:
https://doaj.org/article/ed998ad0ca5e4597b77557991b2f06bf
Publikováno v:
Antibiotics, Vol 10, Iss 1148, p 1148 (2021)
Antibiotics
Volume 10
Issue 10
Antibiotics
Volume 10
Issue 10
To explore whether combined treatments with daptomycin and gentamicin can prevent the development of Staphylococcus aureus resistance, and whether the possible restriction is associated with changes in antibiotic mutant prevention concentrations (MPC
Publikováno v:
The Journal of Antibiotics. 73:101-107
To predict the effects of combined use of antibiotics on their pharmacodynamics, the susceptibility of Staphylococcus aureus to daptomycin–rifampicin combinations was tested at concentration ratios equal to the ratios of daptomycin and rifampicin 2
Autor:
Stephen H. Zinner, Elena N. Strukova, Svetlana A Dovzhenko, Alexander A. Firsov, Yury A. Portnoy, Maria V Golikova, Mikhail B Kobrin
Publikováno v:
Journal of Chemotherapy. 31:320-328
The search for optimal predictors of anti-mutant effects remains a pressing problem in studies of antibiotic-associated bacterial resistance. To relate the emergence of bacterial resistance with the antibiotic mutant prevention concentration (MPC), a
Autor:
Mikhail B Kobrin, Elena N. Strukova, Maria V Golikova, Alexander A. Firsov, Yury A. Portnoy, Stephen H. Zinner, Svetlana A Dovzhenko
Publikováno v:
Journal of Chemotherapy. 31:252-260
Current knowledge of the emergence of Streptococcus pneumoniae resistance during treatment with aminopenicillins and macrolides is limited. In particular, clinical reports on isolation of azithromycin-resistant mutants do not relate their enrichment
Autor:
Yury A. Portnoy, Elena N. Strukova, Maria V Golikova, Kamilla N Alieva, Stephen H. Zinner, Alexander A. Firsov
Publikováno v:
The Journal of antimicrobial chemotherapy. 76(7)
Objectives To explore whether linezolid/daptomycin combinations can restrict Staphylococcus aureus resistance and if this restriction is associated with changes in the mutant prevention concentrations (MPCs) of the antibiotics in combination, the enr
Autor:
Kamilla N Alieva, Svetlana A Dovzhenko, Maria V Golikova, Mikhail B Kobrin, Yury A. Portnoy, Stephen H. Zinner, Alexander A. Firsov
Publikováno v:
Journal of Chemotherapy. 30:364-370
To explore the relationship between pharmacokinetic variables and enterococcal resistance to linezolid, a vancomycin-resistant strain whose mutant prevention concentration (MPC) exceeded the MIC by two fold was selected among six clinical isolates of
Autor:
Elena N. Strukova, Maria V Golikova, Yury A. Portnoy, Kamilla N Alieva, Alexander A. Firsov, Stephen H. Zinner
Publikováno v:
The Journal of Antibiotics. 71:514-521
To explore if the time inside the mutant selection window (TMSW) is a reliable predictor of emergence of bacterial resistance to linezolid, mixed inocula of each of three methicillin-resistant Staphylococcus aureus strains (MIC of linezolid 2 μg ml