Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Yurong CHENG"'
Autor:
Sara Monteiro-Martins, Rosalie B T M Sterenborg, Oleg Borisov, Nora Scherer, Yurong Cheng, Marco Medici, Anna Köttgen, Alexander Teumer
Publikováno v:
European Thyroid Journal, Vol 13, Iss 3, Pp 1-15 (2024)
Introduction: Thyroid hormones have systemic effects on the human body and play a key role in the development and function of virtually all tissues. They are regulated via the hypothalamic–pituitary–thyroid (HPT) axis and have a heritable compone
Externí odkaz:
https://doaj.org/article/2474f3f5ed0d4e2ead6423add33f17bf
Publikováno v:
Taiyuan Ligong Daxue xuebao, Vol 55, Iss 1, Pp 155-162 (2024)
Purposes To address the imbalance between supply and demand in traditional single platform task assignment, Cross Online Matching (COM) has emerged as a novel solution that allows multiple similar platforms to establish cooperative relationships and
Externí odkaz:
https://doaj.org/article/b02fbd4723d34cb8b9b7587f81dd02a3
Autor:
Yaoxian Xiang, Li Wang, Yurong Cheng, Huanjuan An, Chan Zhang, Jing Wang, Yingying Tong, Dong Yan
Publikováno v:
Global Medical Genetics, Vol 10, Iss 04, Pp 388-394 (2023)
The aim of the study was to evaluate the potential diagnostic and prognostic value of gene, Poly A-Binding Protein Interacting Protein 2B (PAIP2B) in pancreatic cancer. We used the gene expression data and clinical information of pancreatic adenocarc
Externí odkaz:
https://doaj.org/article/01420ceafc0742079c5ab35501664495
Publikováno v:
Array, Vol 21, Iss , Pp 100331- (2024)
Information extraction (IE) aims to discover and extract valuable information from unstructured text. This problem can be decomposed into two subtasks: named entity recognition (NER) and relation extraction (RE). Although the IE problem has been stud
Externí odkaz:
https://doaj.org/article/99782168a336458eb98642d421f48a6b
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background There are many studies indicating that alterations in the abundance of certain gut microbiota are associated with colorectal cancer (CRC). However, a causal relationship has not been identified due to confounding factors such as l
Externí odkaz:
https://doaj.org/article/467deffaa8e049efa8e475af96b35fef
Autor:
Yingying Tong, Zheng Zhang, Yurong Cheng, Jing Yang, Cong Fan, Xuyang Zhang, Jiandong Yang, Li Wang, Dong Guo, Dong Yan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-13 (2022)
Abstract The transcriptional regulator nuclear factor of activated T-cells, cytoplasmic 3 (NFATc3) is constitutively activated in several cancer types and plays important roles in cancer development and progression. Heavily phosphorylated NFATc3 resi
Externí odkaz:
https://doaj.org/article/2409bf8740aa4ddba508cc29527156ca
Autor:
Yong Li, Yurong Cheng, Francesco Consolato, Guglielmo Schiano, Michael R. Chong, Maik Pietzner, Ngoc Quynh H. Nguyen, Nora Scherer, Mary L. Biggs, Marcus E. Kleber, Stefan Haug, Burulça Göçmen, Marie Pigeyre, Peggy Sekula, Inga Steinbrenner, Pascal Schlosser, Christina B. Joseph, Jennifer A. Brody, Morgan E. Grams, Caroline Hayward, Ulla T. Schultheiss, Bernhard K. Krämer, Florian Kronenberg, Annette Peters, Jochen Seissler, Dominik Steubl, Cornelia Then, Matthias Wuttke, Winfried März, Kai-Uwe Eckardt, Christian Gieger, Eric Boerwinkle, Bruce M. Psaty, Josef Coresh, Peter J. Oefner, Guillaume Pare, Claudia Langenberg, Jürgen E. Scherberich, Bing Yu, Shreeram Akilesh, Olivier Devuyst, Luca Rampoldi, Anna Köttgen
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
Uromodulin (UMOD) is a major risk gene for monogenic and complex forms of kidney disease. The encoded kidney-specific protein uromodulin is highly abundant in urine and related to chronic kidney disease, hypertension, and pathogen defense. To gain in
Externí odkaz:
https://doaj.org/article/214e08c2c25c48b684ea1de9af2965d4
Autor:
Yurong Cheng, Yong Li, Nora Scherer, Franziska Grundner-Culemann, Terho Lehtimäki, Binisha H Mishra, Olli T Raitakari, Matthias Nauck, Kai-Uwe Eckardt, Peggy Sekula, Ulla T Schultheiss, GCKD investigators
Publikováno v:
PLoS Genetics, Vol 18, Iss 4, p e1010139 (2022)
Osteopontin (OPN), encoded by SPP1, is a phosphorylated glycoprotein predominantly synthesized in kidney tissue. Increased OPN mRNA and protein expression correlates with proteinuria, reduced creatinine clearance, and kidney fibrosis in animal models
Externí odkaz:
https://doaj.org/article/b8d6a12a01274495a88c227f515c5b84
Autor:
Yurong Cheng, Pascal Schlosser, Johannes Hertel, Peggy Sekula, Peter J. Oefner, Ute Spiekerkoetter, Johanna Mielke, Daniel F. Freitag, Miriam Schmidts, GCKD Investigators, Florian Kronenberg, Kai-Uwe Eckardt, Ines Thiele, Yong Li, Anna Köttgen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Metabolites are indicators of health and disease; genetic studies can reveal variants influencing their levels. Here, the authors investigate the contribution of rare, exonic variants on the levels of urine metabolites and generate predictions on met
Externí odkaz:
https://doaj.org/article/b5d5b7f5988e4fe4b8e179a7a1c34fcb
Autor:
Li Wang, Xiaomo Li, Yurong Cheng, Jing Yang, Si Liu, Tonghui Ma, Li Luo, Yanping Hu, Yi Cai, Dong Yan
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
HER2 amplification/overexpression is a common driver in a variety of cancers including gallbladder cancer (GBC). For patients with metastatic GBC, chemotherapy remains the standard of care with limited efficacy. The combination of HER2 antibody trast
Externí odkaz:
https://doaj.org/article/a183d56467c24ebbbf14340089e976bb