Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yuriy Sverchkov"'
Autor:
Yuriy Sverchkov, Mark Craven
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 6, p e1005466 (2017)
Various types of biological knowledge describe networks of interactions among elementary entities. For example, transcriptional regulatory networks consist of interactions among proteins and genes. Current knowledge about the exact structure of such
Externí odkaz:
https://doaj.org/article/a9e108e4220f49bb908b36cf82b87815
Autor:
Jarred W. Rensvold, Evgenia Shishkova, Yuriy Sverchkov, Ian J. Miller, Arda Cetinkaya, Angela Pyle, Mateusz Manicki, Dain R. Brademan, Yasemin Alanay, Julian Raiman, Adam Jochem, Paul D. Hutchins, Sean R. Peters, Vanessa Linke, Katherine A. Overmyer, Austin Z. Salome, Alexander S. Hebert, Catherine E. Vincent, Nicholas W. Kwiecien, Matthew J. P. Rush, Michael S. Westphall, Mark Craven, Nurten A. Akarsu, Robert W. Taylor, Joshua J. Coon, David J. Pagliarini
Publikováno v:
Nature
Mitochondria are epicentres of eukaryotic metabolism and bioenergetics. Pioneering efforts in recent decades have established the core protein componentry of these organelles(1) and have linked their dysfunction to more than 150 distinct disorders(2,
Autor:
Michael R. Sussman, Perry J. Pickhardt, Yuriy Sverchkov, Melanie M. Ivancic, Mark Craven, Mark Reichelderfer, Gregory D. Kennedy, Bryant Megna
Publikováno v:
J Surg Res
Background A major roadblock to reducing the mortality of colorectal cancer (CRC) is prompt detection and treatment, and a simple blood test is likely to have higher compliance than all of the current methods. The purpose of this report is to examine
Autor:
Alexander, Cobian, Madeline, Abbott, Akshay, Sood, Yuriy, Sverchkov, Lawrence, Hanrahan, Theresa, Guilbert, Mark, Craven
Publikováno v:
AMIA Jt Summits Transl Sci Proc
Asthma is a prevalent chronic respiratory condition, and acute exacerbations represent a significant fraction of the economic and health-related costs associated with asthma. We present results from a novel study that is focused on modeling asthma ex
Publikováno v:
J Comput Biol
Lecture Notes in Computer Science ISBN: 9783319899282
RECOMB
Lecture Notes in Computer Science ISBN: 9783319899282
RECOMB
Advances in systems biology have made clear the importance of network models for capturing knowledge about complex relationships in gene regulation, metabolism, and cellular signaling. A common approach to uncovering biological networks involves perf
Autor:
Muruhan Rathinam, Yuriy Sverchkov
Publikováno v:
Bulletin of Mathematical Biology. 81:2849-2872
We study the dynamics of flagellar growth in eukaryotes where intraflagellar transporters (IFT) play a crucial role. First we investigate a stochastic version of the original balance point model where a constant number of IFT particles move up and do
Autor:
Jacqueline A. Cuellar, K. E. Lee, Curtis R. Brandt, Yuriy Sverchkov, Aaron W. Kolb, Mark Craven
Publikováno v:
Journal of Virology. 89:7214-7223
Herpes simplex virus 1 (HSV-1) causes recurrent mucocutaneous ulcers and is the leading cause of infectious blindness and sporadic encephalitis in the United States. HSV-1 has been shown to be highly recombinogenic; however, to date, there has been n
Autor:
Yuriy Sverchkov, Gregory F. Cooper
Publikováno v:
Advances in Intelligent Data Analysis XIV ISBN: 9783319244648
IDA
IDA
We present a novel approach to the problem of detecting multivariate statistical differences across groups of data. The need to compare data in a multivariate manner arises naturally in observational studies, randomized trials, comparative effectiven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d04aa7b68b2c7c3b6c88f097f0b898
https://doi.org/10.1007/978-3-319-24465-5_24
https://doi.org/10.1007/978-3-319-24465-5_24
Publikováno v:
IHI
We present a novel method for obtaining a concise and mathematically grounded description of multivariate differences between a pair of clinical datasets. Often data collected under similar circumstances reflect fundamentally different patterns. For
Publikováno v:
BMC Medical Informatics and Decision Making
BMC Medical Informatics and Decision Making, Vol 12, Iss 1, p 22 (2012)
BMC Medical Informatics and Decision Making, Vol 12, Iss 1, p 22 (2012)
Background The task of spatial cluster detection involves finding spatial regions where some property deviates from the norm or the expected value. In a probabilistic setting this task can be expressed as finding a region where some event is signific