Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yuriy Pyatkivskyy"'
Autor:
Kristin R. Wildsmith, Jacob M. Basak, Bruce W. Patterson, Yuriy Pyatkivskyy, Jungsu Kim, Kevin E. Yarasheski, Jennifer X. Wang, Kwasi G. Mawuenyega, Hong Jiang, Maia Parsadanian, Hyejin Yoon, Tom Kasten, Wendy C. Sigurdson, Chengjie Xiong, Alison Goate, David M. Holtzman, Randall J. Bateman
Publikováno v:
PLoS ONE, Vol 7, Iss 7 (2012)
Externí odkaz:
https://doaj.org/article/a8ec821c68c24b83a9e190c8dd65f3ec
Autor:
Kristin R Wildsmith, Jacob M Basak, Bruce W Patterson, Yuriy Pyatkivskyy, Jungsu Kim, Kevin E Yarasheski, Jennifer X Wang, Kwasi G Mawuenyega, Hong Jiang, Maia Parsadanian, Hyejin Yoon, Tom Kasten, Wendy C Sigurdson, Chengjie Xiong, Alison Goate, David M Holtzman, Randall J Bateman
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38013 (2012)
Apolipoprotein E (ApoE) is the strongest genetic risk factor for Alzheimer's disease and has been implicated in the risk for other neurological disorders. The three common ApoE isoforms (ApoE2, E3, and E4) each differ by a single amino acid, with Apo
Externí odkaz:
https://doaj.org/article/47c819a5a734458c9ad86a8544d5822a
Publikováno v:
European Journal of Mass Spectrometry. 20:337-344
Gas-phase ion–molecule reactions (IMR) of various boron- and silicon-containing neutrals were investigated as a potential route for detecting phosphorylation within peptides in the negative ion mode. Trimethyl borate (TMB), triethyl borate (TEB) an
Autor:
Guoxin Wu, Kristin R. Wildsmith, Andrew Stamford, Kevin E. Yarasheski, Matthew E. Kennedy, David B. Gilberto, Yuriy Pyatkivskyy, Randall J. Bateman, Daniel J. Holder, Mary J. Savage, Robert Chott, Debra A. McLoughlin, Justyna Dobrowolska, Bruce W. Patterson, Mandy Dancho, Tom Kasten, Vitaliy Ovod, Parker Mathers, Maria S. Michener, Christina Lennox, Brad E. Smith
Publikováno v:
Journal of Neuroscience. 34:8336-8346
BACE, a β-secretase, is an attractive potential disease-modifying therapeutic strategy for Alzheimer's disease (AD) as it results directly in the decrease of amyloid precursor protein (APP) processing through the β-secretase pathway and a lowering
Publikováno v:
European Journal of Mass Spectrometry. 20:177-183
Gas-phase ion-molecule reactions of four boron-containing neutrals were explored as a means for differentiation between isobaric phospho- and sulfocarbohydrates. Phosphorylation and sulfation impose an addition of 80 Da to the molecular mass, so for
Autor:
Victor Ryzhov, Yuriy Pyatkivskyy
Publikováno v:
Rapid Communications in Mass Spectrometry. 22:1288-1294
We report for the first time a coupling of gas-phase ion-molecule reactions with chromatographic separations on a quadrupole ion trap mass spectrometer. The interface was accomplished by using a pulsed valve for the introduction of a volatile neutral
Autor:
Matthew E. Kennedy, Brad Smith, Guoxin Wu, Kevin E. Yarasheski, Christina Lennox, Randall J. Bateman, Justyna Dobrowolska, Dan Holder, Andrew Stamford, Yuriy Pyatkivskyy, Kristin R. Wildsmith, Mandy Dancho, Tom Kasten, Maria S. Michener, Vitaliy Ovod, Parker Mathers, Debra A. McLoughlin, Bruce W. Patterson, David B. Gilberto, Robert Chott, Mary J. Savage
Publikováno v:
Alzheimer's & Dementia. 9
Autor:
Kwasi G. Mawuenyega, Hong Jiang, Jungsu Kim, Chengjie Xiong, Jacob M. Basak, Randall J. Bateman, Tom Kasten, David M. Holtzman, Wendy Sigurdson, Yuriy Pyatkivskyy, Jennifer X. Wang, Alison Goate, Kristin R. Wildsmith, Maia Parsadanian, Kevin E. Yarasheski, Hyejin Yoon, Bruce W. Patterson
Publikováno v:
PLoS ONE, Vol 7, Iss 7 (2012)
PLoS ONE
PLoS ONE
Description: Due to errors introduced in the production process, the Supporting Information files were excluded. They can be found here: Table S1: [^]
Autor:
Maia Parsadanian, Bruce W. Patterson, Hong Jiang, David M. Holtzman, Randall J. Bateman, Jungsu Kim, Jacob M. Basak, Kristin R. Wildsmith, Yuriy Pyatkivskyy
Publikováno v:
Molecular Neurodegeneration, Vol 7, Iss 1, p 14 (2012)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background Abnormal proteostasis due to alterations in protein turnover has been postulated to play a central role in several neurodegenerative diseases. Therefore, the development of techniques to quantify protein turnover in the brain is critical f
Autor:
Yuriy Pyatkivskyy, David M. Holtzman, Chengjie Xiong, Hong Jiang, Kevin E. Yarasheski, Bruce W. Patterson, Tom Kasten, Jungsu Kim, Jennifer X. Wang, Jacob M. Basak, Hyejin Yoon, Kwasi G. Mawuenyega, Kristin R. Wildsmith, Randall J. Bateman, Alison Goate, Wendy Sigurdson, Maia Parsadanian
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38013 (2012)
PLoS ONE
PLoS ONE
Apolipoprotein E (ApoE) is the strongest genetic risk factor for Alzheimer's disease and has been implicated in the risk for other neurological disorders. The three common ApoE isoforms (ApoE2, E3, and E4) each differ by a single amino acid, with Apo