Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Yuriy, Alexandrov"'
Autor:
Luca Guglielmi, Claire Heliot, Sunil Kumar, Yuriy Alexandrov, Ilaria Gori, Foteini Papaleonidopoulou, Christopher Barrington, Philip East, Andrew D. Economou, Paul M. W. French, James McGinty, Caroline S. Hill
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The role of the transcriptional effector SMAD4 in vertebrate embryo development remains unresolved. Here the authors show that in the absence of Smad4, dorsal/ventral embryo patterning is disrupted due to the loss of BMP signaling, while Nodal signal
Externí odkaz:
https://doaj.org/article/c3a7ce8f93434e77b3526dc4eb45c12f
Autor:
Edwin Garcia, Jonathan Lightley, Sunil Kumar, Ranjan Kalita, Frederik Gőrlitz, Yuriy Alexandrov, Terry Cook, Christopher Dunsby, Mark AA Neil, Candice A Roufosse, Paul MW French
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 5, Pp 438-445 (2021)
Abstract Electron microscopy (EM) following immunofluorescence (IF) imaging is a vital tool for the diagnosis of human glomerular diseases, but the implementation of EM is limited to specialised institutions and it is not available in many countries.
Externí odkaz:
https://doaj.org/article/039158cc4e144613903b7125dc431ad2
Autor:
Jonathan Lai, Richard Woodward, Yuriy Alexandrov, Qurratul Ain Munnee, Christoph C Lees, Ravi Vaidyanathan, Niamh C Nowlan
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0195728 (2018)
Fetal movements (FM) are a key factor in clinical management of high-risk pregnancies such as fetal growth restriction. While maternal perception of reduced FM can trigger self-referral to obstetric services, maternal sensation is highly subjective.
Externí odkaz:
https://doaj.org/article/41784fc1f7374bceb76a700197f0165f
Autor:
R. Kalita, Yuriy Alexandrov, Vicky Bousgouni, Christopher Dunsby, Edwin Garcia, Seth Flaxman, Jonathan Lightley, Peter J. Barnes, Arinbjörn Kolbeinsson, Sunil Kumar, Paul M. W. French, Chris Bakal, Riccardo Wysoczanski, Louise E Donnelly, Frederik Görlitz, Mark A. A. Neil
Publikováno v:
Journal of microscopyREFERENCES. 288(2)
We presenta robust, long-range optical autofocus system for microscopy utilizing machine learning. This can be useful for experiments with long image data acquisition times that may be impacted by defocusing resulting from drift of components, for ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6efe367fcadaaf4eb3505067d93d76
https://pubmed.ncbi.nlm.nih.gov/34089183
https://pubmed.ncbi.nlm.nih.gov/34089183
Autor:
Frederik Gőrlitz, Paul M. W. French, Jonathan Lightley, Yuriy Alexandrov, Candice Roufosse, Terry Cook, R. Kalita, Christopher Dunsby, Sunil Kumar, Edwin Garcia, Mark A. A. Neil
Publikováno v:
The Journal of Pathology: Clinical Research
The Journal of Pathology: Clinical Research, Vol 7, Iss 5, Pp 438-445 (2021)
The Journal of Pathology: Clinical Research, Vol 7, Iss 5, Pp 438-445 (2021)
Electron microscopy (EM) following immunofluorescence (IF) imaging is a vital tool for the diagnosis of human glomerular diseases, but the implementation of EM is limited to specialised institutions and it is not available in many countries. Recent p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfb32e4a95dfacae4b5ba112409d686
https://pubmed.ncbi.nlm.nih.gov/34018698
https://pubmed.ncbi.nlm.nih.gov/34018698
Autor:
Edwin Garcia, Riccardo Wysoczanski, Yuriy Alexandrov, Chris Bakal, Frederik Görlitz, Christopher Dunsby, Jonathan Lightley, Arinbjörn Kolbeinsson, Paul M. W. French, Peter J. Barnes, Louise E Donnelly, Mark A. A. Neil, Seth Flaxman, R. Kalita, Vicky Bousgouni, Sunil Kumar
We present a robust, long-range optical autofocus system for microscopy utilizing machine learning. This can be useful for experiments with long image data acquisition times that may be impacted by defocusing resulting from drift of components, e.g.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc1e41afa8d78bf7fb0731e8d4c4275c
https://doi.org/10.1101/2021.03.05.431171
https://doi.org/10.1101/2021.03.05.431171
Autor:
Christopher Dunsby, Yuriy Alexandrov, Riccardo Wysoczanski, Paul M. W. French, Jonathan Lightley, Arinbjörn Kolbeinsson, L. Donelly, Edwin Garcia, Seth Flaxman, Mark A. A. Neil, Chris Bakal, R. Kalita, Peter J. Barnes, Frederik Görlitz, Vicky Bousgouni, Sunil Kumar
Publikováno v:
Scopus-Elsevier
We present a robust, low-cost neural network-based optical autofocus system that can operate over a range of ±100µm with submicron precision, enabling automated high-content super-resolved imaging with a 1.3 NA objective lens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb3f922f455ff2b4b8ef33b04d40091
https://doi.org/10.1364/ecbo.2021.es1a.1
https://doi.org/10.1364/ecbo.2021.es1a.1
Autor:
Sean C Warren, Anca Margineanu, Dominic Alibhai, Douglas J Kelly, Clifford Talbot, Yuriy Alexandrov, Ian Munro, Matilda Katan, Chris Dunsby, Paul M W French
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70687 (2013)
Fluorescence lifetime imaging (FLIM) is widely applied to obtain quantitative information from fluorescence signals, particularly using Förster Resonant Energy Transfer (FRET) measurements to map, for example, protein-protein interactions. Extractin
Externí odkaz:
https://doaj.org/article/3c32e3b4a7934189900676da53ff1637
Autor:
Louise E. Donnelly, Simon Johnson, Sunil Kumar, Mark A. A. Neil, Frederik Görlitz, Paul M. W. French, Christopher Dunsby, Jonathan Lightley, Edwin Garcia, Yuriy Alexandrov, Ian Munro, Riccardo Wysoczanski, Martin Kehoe, Callum Hollick, Peter J. Barnes, Jeremy Graham
Publikováno v:
Single Molecule Spectroscopy and Superresolution Imaging XIII.
Super-resolved microscopy techniques have overcome the diffraction limit to provide image resolutions approaching the scale of fluorescent labels. However, many of these techniques require significant experimental resources and expertise and impose l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2adbc1b27860aec595ae33393e89cccf
https://doi.org/10.1117/12.2550682
https://doi.org/10.1117/12.2550682
Autor:
Christopher Dunsby, Wenjun Guo, Edwin Garcia, Ian Munro, Frederik Görlitz, Yuriy Alexandrov, Paul M. W. French, Hugh Sparks, Sunil Kumar, Alessandro Sardini, Sean C. Warren, Peter H. Thorpe, David Carling, George Chennell, Douglas J. Kelly
Publikováno v:
Multiphoton Microscopy in the Biomedical Sciences XX.
Fluorescence lifetime imaging (FLIM) provides a means to contrast different molecular species and to map variations in the local fluorophore molecular environment, including to read out Forster resonant energy transfer (FRET), e.g. to assay protein i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::442c14a04f8dc49c601dbff7cf0b1993
https://doi.org/10.1117/12.2547517
https://doi.org/10.1117/12.2547517