Myc Supports Self-Renewal of Basal Cells in the Esophageal Epithelium

Autor: Tomoaki Hishida, Eric Vazquez-Ferrer, Yuriko Hishida-Nozaki, Yuto Takemoto, Fumiyuki Hatanaka, Kei Yoshida, Javier Prieto, Sanjeeb Kumar Sahu, Yuta Takahashi, Pradeep Reddy, David D. O’Keefe, Concepcion Rodriguez Esteban, Paul S. Knoepfler, Estrella Nuñez Delicado, Antoni Castells, Josep M. Campistol, Ryuji Kato, Hiroshi Nakagawa, Juan Carlos Izpisua Belmonte

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

It is widely believed that cellular senescence plays a critical role in both aging and cancer, and that senescence is a fundamental, permanent growth arrest that somatic cells cannot avoid. Here we show that Myc plays an important role in self-renewa

Externí odkaz: https://doaj.org/article/31205045cd044c04b4a97467e784b2c0

Mutations in foregut SOX2+ cells induce efficient proliferation via CXCR2 pathway

Autor: Tomoaki Hishida, Eric Vazquez-Ferrer, Yuriko Hishida-Nozaki, Ignacio Sancho-Martinez, Yuta Takahashi, Fumiyuki Hatanaka, Jun Wu, Alejandro Ocampo, Pradeep Reddy, Min-Zu Wu, Laurie Gerken, Reuben J. Shaw, Concepcion Rodriguez Esteban, Christopher Benner, Hiroshi Nakagawa, Pedro Guillen Garcia, Estrella Nuñez Delicado, Antoni Castells, Josep M. Campistol, Guang-Hui Liu, Juan Carlos Izpisua Belmonte

Publikováno v: Protein & Cell, Vol 10, Iss 7, Pp 485-495 (2019)

Abstract Identification of the precise molecular pathways involved in oncogene-induced transformation may help us gain a better understanding of tumor initiation and promotion. Here, we demonstrate that SOX2+ foregut epithelial cells are prone to onc

Externí odkaz: https://doaj.org/article/650bfe1468004174b4f346e6bcc81813

Establishment of human iPSC-based models for the study and targeting of glioma initiating cells

Autor: Ignacio Sancho-Martinez, Emmanuel Nivet, Yun Xia, Tomoaki Hishida, Aitor Aguirre, Alejandro Ocampo, Li Ma, Robert Morey, Marie N. Krause, Andreas Zembrzycki, Olaf Ansorge, Eric Vazquez-Ferrer, Ilir Dubova, Pradeep Reddy, David Lam, Yuriko Hishida, Min-Zu Wu, Concepcion Rodriguez Esteban, Dennis O’Leary, Geoffrey M. Wahl, Inder M. Verma, Louise C. Laurent, Juan Carlos Izpisua Belmonte

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)

Glioma can originate from the transformation of neural progenitor cells into glioma initiating cells. Here, the authors demonstrate the use of induced pluripotent stem cells as a suitable model for generating neural progenitor cells, which can be sub

Externí odkaz: https://doaj.org/article/1fb354a0ffc8422d8d9d844eb2315537

αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model

Autor: Juan Manuel López-Alcorocho, Tomoaki Hishida, George M. Church, Chao Wang, Pedro Guillén-García, Yuriko Hishida, Isabel Guillén-Vicente, Elena Rodríguez-Iñigo, Reyna Hernández-Benítez, Akihisa Sakamoto, Concepcion Rodriguez Esteban, Fumiyuki Hatanaka, Marta Guillén-Vicente, Javier Prieto, Estrella Núñez-Delicado, Noah Davidsohn, Ling Huang, Paloma Martinez-Redondo, Kensaku Shojima, Pradeep Reddy, Masakazu Kurita, Juan Carlos Izpisua Belmonte, Amy N. Nemeth, Takashi Lezaki, Maxim N. Shokhirev, Cuiqing Zhong, Isabel Guillen-Guillen, Josep M. Campistol, Guang-Hui Liu

Publikováno v: Protein & Cell, Vol 11, Iss 3, Pp 219-226 (2020)
Protein & Cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98460a7583fd7a395ceb27bb251cb4f
https://doaj.org/article/37783dd84b5348adb38d66fcf9ff720f

Mutations in foregut SOX2+ cells induce efficient proliferation via CXCR2 pathway

Autor: Concepcion Rodriguez Esteban, Fumiyuki Hatanaka, Reuben J. Shaw, Christopher Benner, Antoni Castells, Josep M. Campistol, Min-Zu Wu, Pradeep Reddy, Ignacio Sancho-Martinez, Yuta Takahashi, Estrella Nuñez Delicado, Laurie Gerken, Juan Carlos Izpisua Belmonte, Tomoaki Hishida, Guang-Hui Liu, Hiroshi Nakagawa, Alejandro Ocampo, Pedro Guillen Garcia, Yuriko Hishida-Nozaki, Eric Vazquez-Ferrer, Jun Wu

Publikováno v: Protein & Cell, Vol 10, Iss 7, Pp 485-495 (2019)
Protein & cell, vol 10, iss 7
Protein & Cell, vol. 10, no. 7, pp. 485-495
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Protein & Cell

Identification of the precise molecular pathways involved in oncogene-induced transformation may help us gain a better understanding of tumor initiation and promotion. Here, we demonstrate that SOX2+ foregut epithelial cells are prone to oncogenic tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b39f3425ea9f34f1305e80d82153f19
http://link.springer.com/article/10.1007/s13238-019-0630-3