A genomic‐augmented multivariate prognostic model for the survival of natural‐killer/T‐cell lymphoma patients from an international cohort

Autor: Jing Quan Lim, Dachuan Huang, Jason Yongsheng Chan, Yurike Laurensia, Esther Kam Yin Wong, Daryl Ming Zhe Cheah, Burton Kuan Hui Chia, Wen‐Yu Chuang, Ming‐Chung Kuo, Yi‐Jiun Su, Qing‐qing Cai, Yanfen Feng, Huilan Rao, Li‐Na Feng, Pan‐Pan Wei, Jie‐Rong Chen, Bo‐Wei Han, Guo‐Wang Lin, Jun Cai, Yu Fang, Jing Tan, Huangming Hong, Yanhui Liu, Fen Zhang, Wenyu Li, Michelle L. M. Poon, Siok‐Bian Ng, Anand Jeyasekharan, Jeslin Chian Hung Ha, Lay Poh Khoo, Suk Teng Chin, Wan Lu Pang, Rebecca Kee, Chee Leong Cheng, Nicholas Francis Grigoropoulos, Tiffany Tang, Miriam Tao, Mohamad Farid, Kia Joo Puan, Jie Xiong, Wei‐Li Zhao, Chiea Chuen Khor, William Hwang, Won Seog Kim, Elias Campo, Patrick Tan, Bin Tean Teh, Wee‐Joo Chng, Olaf Rötzschke, Thomas Tousseyn, Hui‐Qiang Huang, Steve Rozen, Soon Thye Lim, Lee‐Yung Shih, Jin‐Xin Bei, Choon Kiat Ong

Publikováno v: American Journal of Hematology. 97:1159-1169

With lowering costs of sequencing and genetic profiling techniques, genetic drivers can now be detected readily in tumors but current prognostic models for Natural-killer/T cell lymphoma (NKTCL) have yet to fully leverage on them for prognosticating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879985b3317f0ecbd35d0a8c5fc2fff8
https://doi.org/10.1002/ajh.26636

Application of an ex-vivo drug sensitivity platform towards achieving complete remission in a refractory T-cell lymphoma

Autor: Daryl Ming Zhe Cheah, Sanjay de Mel, Masturah Bte Mohd Rashid, Jing Quan Lim, Edward Kai-Hua Chow, Choon Kiat Ong, Siok Bian Ng, Soo Yong Tan, Chun Tsu Lee, Soon Thye Lim, Joanne Lee, Wee Joo Chng, Xin Liu, Hoi-Yin Loi, Yi Ching Yuen, Tiffany Tang, Xi Yun Zhang, Li Mei Poon, Yurike Laurensia, Lip Kun Tan, Dachuan Huang, Anand D. Jeyasekharan, Esther H. L. Chan, Jasmine Goh, Esther Kam Yin Wong, Wan Lu Pang, Yen Lin Chee, Burton Kuan Hui Chia

Publikováno v: Blood Cancer Journal, Vol 10, Iss 1, Pp 1-5 (2020)
Blood Cancer Journal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74131b60825389c7226e8da1c9dcbc74
http://link.springer.com/article/10.1038/s41408-020-0276-7

No association between ECSIT germline mutations and hemophagocytic lymphohistiocytosis in natural killer/T-cell lymphoma

Autor: Yuh Shan Lee, Chee Leong Cheng, Yurike Laurensia, Daryl Tan Chen Lung, Jing Quan Lim, Colin Phipps, Dachuan Huang, Burton Kuan Hui Chia, Shih Ly, Yi-Jiun Su, Yeow Tee Goh, Ming-Chung Kuo, Daryl Cheah Ming Zhe, Choon Kiat Ong, Sahil Saraf, Wen-Yu Chuang, Nicholas Francis Grigoropoulos, Soon Thye Lim, Shin Yeu Ong, Chandramouli Nagarajan

Publikováno v: Haematologica. 106:1737-1739

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4346b5488615a0fef4d2ba1cb88fe3f4
https://doi.org/10.3324/haematol.2020.269209

Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma

Autor: Shu Wei Chen, Yun Miao Guo, Jin Xin Bei, Li Na Feng, Rou Jun Peng, Hui Qiang Huang, Xiao Yu Zuo, Jing Quan Lim, Qing Qing Cai, Yi Xia, Choon Kiat Ong, Xiao Jun Xia, Burton Kuan Hui Chia, Bo Li, Tao Xia, Soon Thye Lim, Yi Xin Zeng, Mu Sheng Zeng, Ken H. Young, Jie Rong Chen, Yurike Laurensia, Bo Wei Han

Publikováno v: Leukemia

Extranodal natural killer T-cell lymphoma (nasal type; NKTCL) is an aggressive malignancy strongly associated with Epstein-Barr virus (EBV) infection. However, the role of EBV in NKTCL development is unclear, largely due to the lack of information ab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5d00fc8532af2b730740bbf4eca8a4
https://doi.org/10.1038/s41375-018-0324-5

Avelumab for the treatment of relapsed or refractory extranodal NK/T-cell lymphoma: an open-label phase 2 study

Autor: Sang Eun Yoon, Ji Young Lee, Youngil Koh, Duck Cho, Mette Bjerre, Soon Thye Lim, Jing Quan Lim, Seok Jin Kim, Kyung Ju Ryu, Francesco d'Amore, Yurike Laurensia, Won Seog Kim, Junhun Cho, Young Hyeh Ko, Choon Kiat Ong, Marie Beck Enemark

Publikováno v: Kim, S J, Lim, J Q, Laurensia, Y, Cho, J, Yoon, S E, Lee, J Y, Ryu, K J, Ko, Y H, Koh, Y, Cho, D, Lim, S T, Beck Enemark, M, D'amore, F, Bjerre, M, Ong, C K & Kim, W S 2020, ' Avelumab for the treatment of relapsed or refractory extranodal NK/T-cell lymphoma: an open-label phase 2 study ', Blood, vol. 136, no. 24, pp. 2754-2763 . https://doi.org/10.1182/blood.2020007247

This study aimed to assess the efficacy and safety of treatment with avelumab, an anti–programmed death ligand 1 (PD-L1) antibody, in patients with relapsed or refractory extranodal natural killer/T-cell lymphoma (ENKTL). In this phase 2 trial, 21

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffb8cd18a30f3084094acf77b99f4b6
https://pure.au.dk/portal/da/publications/avelumab-for-the-treatment-of-relapsed-or-refractory-extranodal-nktcell-lymphoma-an-openlabel-phase-2-study(088b25b6-d9c4-4edd-bca6-ae0843286f11).html