Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Yurika Saitoh"'
Autor:
Takeharu Sakamoto, Yuya Fukui, Yasumitsu Kondoh, Kaori Honda, Takeshi Shimizu, Toshiro Hara, Tetsuro Hayashi, Yurika Saitoh, Yoshinori Murakami, Jun-ichiro Inoue, Shuichi Kaneko, Hiroyuki Osada, Motoharu Seiki
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Sakomoto et al. identify naphthofluorescein as a mint3 inhibitor that disrupts the Mint3–FIH-1 interaction and attenuates HIF-1 activity. In vivo experiments in mice reveal a reduction in tumor growth with attenuated inflammatory cytokine productio
Externí odkaz:
https://doaj.org/article/19aa786f0153417ab843292a86a3abc2
Autor:
Yoohwa Chung, Yurika Saitoh, Tetsuro Hayashi, Yuya Fukui, Nobuo Terada, Motoharu Seiki, Yoshinori Murakami, Takeharu Sakamoto
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss , Pp 100872- (2020)
Munc-18 interacting protein 3 (Mint3) is an activator of hypoxia-inducible factor-1 in cancer cells, macrophages, and cancer-associated fibroblasts under pathological conditions. However, exactly which cells highly express Mint3 in vivo and whether M
Externí odkaz:
https://doaj.org/article/5e90fbf484454de1a0ddf55ea880d454
Autor:
Mitsuhiko Katoh, Bao Wu, Huy Bang Nguyen, Truc Quynh Thai, Ryo Yamasaki, Haiyan Lu, Anna M. Rietsch, Musab M. Zorlu, Youichi Shinozaki, Yurika Saitoh, Sei Saitoh, Takashi Sakoh, Kazuhiro Ikenaka, Schuichi Koizumi, Richard M. Ransohoff, Nobuhiko Ohno
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Microglia are the resident macrophages of the central nervous system and play complex roles in the milieu of diseases including the primary diseases of myelin. Although mitochondria are critical for cellular functions and survival in the ner
Externí odkaz:
https://doaj.org/article/52abb5ec19ee44a2bc3a37aaeb839825
Autor:
Tomoki, Yamada, Yurika, Saitoh, Kiyokazu, Kametani, Akio, Kamijo, Takeharu, Sakamoto, Nobuo, Terada
Publikováno v:
Histochemistry and Cell Biology. 158:497-511
We previously reported that the membrane skeletal protein 4.1G in the peripheral nervous system transports membrane palmitoylated protein 6 (MPP6), which interacts with the synaptic scaffolding protein Lin7 and cell adhesion molecule 4 (CADM4) in Sch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f1709ab6175bb9850b7d929766bb28
https://doi.org/10.1007/s00418-022-02137-6
https://doi.org/10.1007/s00418-022-02137-6
Autor:
Yuya Fukui, Yasumitsu Kondoh, Jun-ichiro Inoue, Yurika Saitoh, Takeharu Sakamoto, Shuichi Kaneko, Motoharu Seiki, Hiroyuki Osada, Takeshi Shimizu, Toshiro Hara, Yoshinori Murakami, Kaori Honda, Tetsuro Hayashi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology
Communications Biology
Hypoxia-inducible factor-1 (HIF-1) plays essential roles in human diseases, though its central role in oxygen homoeostasis hinders the development of direct HIF-1-targeted pharmacological approaches. Here, we surveyed small-molecule compounds that ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3913eed248a727c14a61eb5add1e3a
https://doaj.org/article/19aa786f0153417ab843292a86a3abc2
https://doaj.org/article/19aa786f0153417ab843292a86a3abc2
Autor:
Shuichi Kaneko, Takeharu Sakamoto, Daisuke Matsubara, Yoshinori Murakami, Yuya Fukui, Noriko Gotoh, Akane Kanamori, Jun-ichiro Inoue, Yurika Saitoh, Motoharu Seiki
Publikováno v:
Oncogene
Pancreatic cancer is one of the most fatal cancers without druggable molecular targets. Hypoxia inducible factor-1 (HIF-1) is a heterodimeric transcriptional factor that promotes malignancy in various cancers including pancreatic cancer. Herein, we f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4166a5b32163c724d1816f942fd38f8e
https://doi.org/10.1038/s41388-020-01423-8
https://doi.org/10.1038/s41388-020-01423-8
Autor:
Yurika Saitoh
Publikováno v:
Anatomical science international. 97(2)
The preparation of histological specimens from animals and humans is a multi-step process comprising tissue collection, fixation, and dehydration, followed by paraffin embedding. Each process can be achieved using different methods and substances. Fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c102b95f2cd0938319e284deb0b1742b
https://pubmed.ncbi.nlm.nih.gov/35038144
https://pubmed.ncbi.nlm.nih.gov/35038144
Autor:
Yurika Saitoh, Yoshinori Murakami, Yuya Fukui, Nobuo Terada, Motoharu Seiki, Yoohwa Chung, Takeharu Sakamoto, Tetsuro Hayashi
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss, Pp 100872-(2020)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Munc-18 interacting protein 3 (Mint3) is an activator of hypoxia-inducible factor-1 in cancer cells, macrophages, and cancer-associated fibroblasts under pathological conditions. However, exactly which cells highly express Mint3 in vivo and whether M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d8c78b8dc1f1e74e84ab7346c3e1d5
http://www.sciencedirect.com/science/article/pii/S2405580820301825
http://www.sciencedirect.com/science/article/pii/S2405580820301825
Autor:
Yurika Saitoh, Yoshinori Murakami, Yuya Fukui, Yoichi Furukawa, Yusuke Matsui, Takeharu Sakamoto, Shuichi Kaneko, Yutaka Suzuki, Masahide Seki, Teppei Shimamura, Jun-ichiro Inoue, Motoharu Seiki, Akane Kanamori, Kiyoshi Yamaguchi, Seiko Yoshino
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Cancer cells adapt to various stress conditions by optimizing gene expression profiles via transcriptional and translational regulation. However, whether and how EXOSC9, a component of the RNA exosome complex, regulates adaptation to stress condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15afdc9b9ecb2b6700c3924c158ae8bb
http://europepmc.org/articles/PMC7283315
http://europepmc.org/articles/PMC7283315
Autor:
Masaki Saito, Marina Hirano, Tomohiro Izumi, Yu Mori, Kentaro Ito, Yurika Saitoh, Nobuo Terada, Takeya Sato, Jun Sukegawa
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 4; Pages: 2094
The primary cilium is a hair-like immotile organelle with specific membrane receptors, including the receptor of Hedgehog signaling, smoothened. The cilium organized in preosteoblasts promotes differentiation of the cells into osteoblasts (osteoblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31cf9cada556f9b6e5195b04011472e1
https://doi.org/10.3390/ijms23042094
https://doi.org/10.3390/ijms23042094