Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yurii Kheylik"'
Autor:
Dmitry Dibchak, Mariya Snisarenko, Artem Mishuk, Oleg Shablykin, Lina Bortnichuk, Oleksii Klymenko-Ulianov, Yurii Kheylik, Iryna Sadkova, Henry Rzepa, Pavel Mykhailiuk
A general approach to 3-azabicyclo[3.1.1]heptanes was unexpectedly discovered. The mechanism, scope, and scalability of this method were studied. The core was incorporated into the structure of the antihistamine drug Rupatidine instead of the pyridin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7e427db48da5435aa4ebec9aa25792a
https://doi.org/10.26434/chemrxiv-2023-jbb0r
https://doi.org/10.26434/chemrxiv-2023-jbb0r
Publikováno v:
Journal of Fluorine Chemistry. 175:73-83
Three novel amines all possessing gem-difluorocyclopropane, secondary amino group and a fused aliphatic cycle were synthesized by difluorocyclopropanation of N-Boc protected enamides. The compounds were stable when amino group was blocked by protonat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df13945d65874f96904054efb1b15411
https://doi.org/10.1016/j.jfluchem.2015.03.008
https://doi.org/10.1016/j.jfluchem.2015.03.008
