Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Yurie Yamada"'
Autor:
Caitlin B. Dingwall, Amy Strickland, Sabrina W. Yum, Aldrin K.Y. Yim, Jian Zhu, Peter L. Wang, Yurie Yamada, Robert E. Schmidt, Yo Sasaki, A. Joseph Bloom, Aaron DiAntonio, Jeffrey Milbrandt
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 23 (2022)
Axon loss contributes to many common neurodegenerative disorders. In healthy axons, the axon survival factor NMNAT2 inhibits SARM1, the central executioner of programmed axon degeneration. We identified 2 rare NMNAT2 missense variants in 2 brothers a
Externí odkaz:
https://doaj.org/article/1463d2560add407bbb4937358ec40312
Autor:
Tong Wu, Jian Zhu, Amy Strickland, Kwang Woo Ko, Yo Sasaki, Caitlin B. Dingwall, Yurie Yamada, Matthew D. Figley, Xianrong Mao, Alicia Neiner, A. Joseph Bloom, Aaron DiAntonio, Jeffrey Milbrandt
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109872- (2021)
Summary: SARM1 is an inducible TIR-domain NAD+ hydrolase that mediates pathological axon degeneration. SARM1 is activated by an increased ratio of NMN to NAD+, which competes for binding to an allosteric activating site. When NMN binds, the TIR domai
Externí odkaz:
https://doaj.org/article/de9f3f8581274b08b0ab0cc8ca1a999f
Autor:
Cintia Yurie Yamada, Danilo Medeiros Eler, Ives Renê Venturini Pola, Almir Olivette Artero, Maurício Araujo Dias
Publikováno v:
Colloquium Exactarum, Vol 9, Iss 1, Pp 14-32 (2017)
Técnicas de classificação como Rede Neural Artificial e Rede Bayesiana são muito utilizadas para a tarefa de reconhecimento de padrões. A maioria delas constrói um padrão e em seguida submete novas instâncias a uma comparação com o padrão
Externí odkaz:
https://doaj.org/article/8e09756537f0488db3d521e3628822d6
Autor:
Jun Nihara, Takehisa Kudo, Kenji Seo, Atsushi Ohazama, Takeyasu Maeda, Miho Terunuma, Izumi Iida, Yurie Yamada, Yutaka Shimomura, Supaluk Trakanant, Masayuki Kurose, Kenji Izumi
Publikováno v:
Neuroscience Research. 173:62-70
Hh signaling has been shown to be activated in intact and injured peripheral nerve. However, the role of Hh signaling in peripheral nerve is not fully understood. In the present study, we observed that Hh signaling responsive cells [Gli1(+) cells] in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7933fddccdc20fa62bef6ad4f2d0cdd3
https://doi.org/10.1016/j.neures.2021.06.003
https://doi.org/10.1016/j.neures.2021.06.003
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169201 (2017)
Brain-derived neurotrophic factor (BDNF), which is released due to nerve injury, is known to promote the natural healing of injured nerves. It is often observed that damage of mandibular canal induces local sclerotic changes in alveolar bone. We repo
Externí odkaz:
https://doaj.org/article/b268784e07e44d48b8fafac0105f6e31
Autor:
A. Joseph Bloom, Amber R. Hackett, Amy Strickland, Yurie Yamada, Joseph Ippolito, Robert E. Schmidt, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt
Schwann cells (SCs) myelinate and provide trophic support to axons in the peripheral nervous system (PNS) and disruption of SC cellular metabolism leads to demyelination and axon degeneration, both symptoms of peripheral neuropathies. The lactate shu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::931b28bc504caaaa78c0a6a61a0ce473
https://doi.org/10.1101/2022.06.29.497865
https://doi.org/10.1101/2022.06.29.497865
Autor:
Isabela Yurie Yamada, Anna Victória Leitgeb Santos de Castro Soares, Beatriz Leite Assis, Bianca Oliveira, Ellen Teodora Coelho Mendes, Gabriela Honorato de Oliveira, Igor de Sousa Oliveira, Laís Maria Peixoto Vieira, Lara Bianca Soares Brandão, Marina Nascimento Gomes, Gilberto Loiola de Vasconcelos
Publikováno v:
Revista Científica Multidisciplinar Núcleo do Conhecimento. :66-86
Contexto: A coinfecção HIV/TB é um dos principais agravantes subnotificados do mundo, perpassando um descaso humanitário de ambas as doenças inseridas em um contexto de alta letalidade. Apesar de medidas profiláticas, essa coinfecção ainda av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::084fca3a18a2f3ce344f1aff81a23e59
https://doi.org/10.32749/nucleodoconhecimento.com.br/saude/analise-epidemiologica
https://doi.org/10.32749/nucleodoconhecimento.com.br/saude/analise-epidemiologica
Autor:
Kelsey L. Krus, Amy Strickland, Yurie Yamada, Laura Devault, Robert E. Schmidt, A. Joseph Bloom, Jeffrey Milbrandt, Aaron DiAntonio
Publikováno v:
Cell reports. 39(13)
TDP-43 mediates proper Stathmin-2 (STMN2) mRNA splicing, and STMN2 protein is reduced in the spinal cord of most patients with amyotrophic lateral sclerosis (ALS). To test the hypothesis that STMN2 loss contributes to ALS pathogenesis, we generated c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2813a830dfb68a91121f259679668b13
https://pubmed.ncbi.nlm.nih.gov/35767949
https://pubmed.ncbi.nlm.nih.gov/35767949
Autor:
Jun Nihara, Makio Saeki, Atsushi Ohazama, Daisuke Matsumaru, Kenji Seo, Takehisa Kudo, Takeyasu Maeda, Yurie Yamada, Masayuki Kurose, Supaluk Trakanant
Publikováno v:
Neuroscience. 432:229-239
Hedgehog (Hh) signaling has been shown to be involved in regulating both intact and injured peripheral nerves. Therefore, it is critical to understand how Hh signaling is regulated in the peripheral nerve. One of the transcription factors of the Hh s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95157094256ed7043ad7951623c82c55
https://doi.org/10.1016/j.neuroscience.2020.02.036
https://doi.org/10.1016/j.neuroscience.2020.02.036
Autor:
Yurie Yamada, Tong Wu, Jeffrey Milbrandt, Amy Strickland, Kwang Woo Ko, Matthew D. Figley, Alicia Neiner, Jian Zhu, Aaron DiAntonio, Xianrong Mao, Caitlin B. Dingwall, Yo Sasaki, A. Joseph Bloom
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109872-(2021)
Cell Rep
Cell Rep
SUMMARYSARM1 is an inducible TIR-domain NAD+ hydrolase that mediates pathological axon degeneration. SARM1 is activated by an increased ratio of NMN to NAD+, which competes for binding to an allosteric activating site. When NMN binds, the TIR domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867fed9ee01fe23f6560a3abd2fefa32
http://www.sciencedirect.com/science/article/pii/S2211124721013395
http://www.sciencedirect.com/science/article/pii/S2211124721013395