Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yurie Futoh"'
Autor:
Yurie Futoh, Hideyo Miyato, Hironori Yamaguchi, Misaki Matsumiya, Rei Takahashi, Yuki Kaneko, Yuki Kimura, Hideyuki Ohzawa, Naohiro Sata, Joji Kitayama, Yoshinori Hosoya
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The vagus nerve is the only pathway for transmitting parasympathetic signals between the brain and thoracoabdominal organs, thereby exhibiting anti-inflammatory functions through the cholinergic anti-inflammatory pathway. Despite often being
Externí odkaz:
https://doaj.org/article/62220152ec8f48409f193568979cdcee
Autor:
Yuki Kaneko, Hideyo Miyato, Mineyuki Tojo, Yurie Futoh, Kazuya Takahashi, Yuki Kimura, Akira Saito, Hideyuki Ohzawa, Hironori Yamaguchi, Naohiro Sata, Joji Kitayama, Yoshinori Hosoya
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The spleen is a key source of circulating and tumor-infiltrating immune cells. However, the effect of splenectomy on tumor growth remains unclear. At 3 weeks after splenectomy, we subcutaneously injected LuM1 cells into BALB/c mice and evalu
Externí odkaz:
https://doaj.org/article/3225aa42bca945ea975c20178115191b
Autor:
YUKO KUMAGAI, YURIE FUTOH, HIDEYO MIYATO, HIDEYUKI OHZAWA, HIRONORI YAMAGUCHI, SHIN SAITO, KENTARO KURASHINA, YOSHINORI HOSOYA, ALAN KAWARAI LEFOR, NAOHIRO SATA, JOJI KITAYAMA
Publikováno v:
In Vivo
Background/Aim: Programmed death-1 (PD-1)/PD-ligand 1 (PD-L1) blockade therapy is widely used for the treatment of patients with metastatic gastric cancer (GC). However, it is unclear how PD-1 antibodies affect the local immunity related to the growt
Autor:
Yurie Futoh, Yuko Kumagai, Hideyo Miyato, Hideyuki Ozawa, Rihito Kanamaru, Ai Sadatomo, Yasuharu Ohnishi, Koji Koinuma, Hisanaga Horie, Hironori Yamaguchi, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama
Publikováno v:
BJS Open. 7
Background Low-density granulocytes (LDGs) have been shown to be increased in the peripheral blood of patients with inflammatory and malignant diseases. This study evaluated LDGs in patients who underwent radical surgery for colorectal cancer (CRC) a
Autor:
Akira Saito, Hideyuki Ohzawa, Yuki Kaneko, Kohei Tamura, Yurie Futoh, Kazuya Takahashi, Yuki Kimura, Rie Kawashima, Hideyo Miyato, Joji Kitayama, Naohiro Sata
Publikováno v:
Cancer Research. 83:1268-1268
Background: Although metformin (Met) is well known to suppress tumor growth, the detailed mechanisms of its anti-tumor effect remain unknown. In recent years, it has been pointed out that tumor-associated neutrophils (TAN) can produce neutrophil extr
Autor:
Kohei Tamura, Hideyo Miyato, Misaki Matsumiya, Rei Takahashi, Yuki Kaneko, Yurie Futoh, Kazuya Takahashi, Yuki Kimura, Akira Saito, Hideyuki Ohzawa, Yasushi Saga, Yuji Takei, Hiroyuki Fujiwara, Joji Kitayama
Publikováno v:
Cancer Research. 83:2266-2266
Objective: High density of tumor-infiltrating lymphocytes (TIL) in the tumor is associated with favorable prognosis of cancer patients. It has been reported that many neutrophils also infiltrate in various tumor tissues as tumor-associated neutrophil
Autor:
Yuki Kimura, Hideyuki Ohzawa, Yuki Kaneko, Kohei Tamura, Yurie Futoh, Kazuya Takahashi, Akira Saito, Mineyuki Tojo, Hideyo Miyato, Joji Kitayama
Publikováno v:
Cancer Research. 82:6284-6284
Background: Mesothelial cells play tumor-promoting roles in the development of peritoneal metastasis (PM) through mesothelial-mesenchymal transition (MMT). We reported miR-29b suppressed MMT of human peritoneal mesothelial cell (HPMC). Methods: MiR-2
Autor:
Akira Saito, Hideyuki Ohzawa, Yuki Kaneko, Kohei Tamura, Yurie Futoh, Kazuya Takahashi, Yuki Kimura, Mineyuki Tojo, Rie Kawashima, Hideyo Miyato, Naohiro Sata, Joji Kitayama
Publikováno v:
Cancer Research. 82:6379-6379
Background: Type2 diabetes mellitus(T2DM) is a risk factor for cancer. Recent studies have shown that DPP-4 inhibitor(DPP-4i) can either promote or suppress cancer progression. However, the detailed mechanisms remain unknown. Here, in this study, we
Autor:
Yuki Kaneko, HIdeyuki Ohzawa, Yuki Kimura, Kohei Tamura, Yurie Futoh, Kazuya Takahashi, Akira Saito, Mineyuki Tojo, Hideyo Miyato, Naohiro Sata, Joji Kitayama
Publikováno v:
Cancer Research. 82:6285-6285
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies and an inherently chemoresistant tumor. Dense fibrotic stroma is a major obstacle for drug delivery to the tumor cells in PDAC. Pancreatic stellate cells (PSCs
Autor:
Kazuya Takahashi, Hideyuki Ohzawa, Yuki Kaneko, Yurie Futoh, Kohei Tamura, Yuki Kimura, Akira Saito, Mineyuki Tojo, Rihito Kanamaru, Hideyo Miyato, Naohiro Sata, Joji Kitayama
Publikováno v:
Cancer Research. 82:6289-6289
Background: Activated neutrophils can produce multiple substances including various enzymes such as neutrophil elastase, myeloperoxidase, as well as many cytokines and reactive oxygen species (ROS). In addition, in some circumstances, they produce ne