Výsledky vyhledávání - "Yuri Zakharov"

Rapid detection and identification of bacteria directly from whole blood with light scattering spectroscopy based biosensor

Autor: Maria Glyavina, Gary L. Horowitz, Lev T. Perelman, Mark F. Coughlan, Le Qiu, Vladimir Turzhitsky, Irving Itzkan, Edward Vitkin, Yuri Zakharov, Umar Khan, Lei Zhang

Publikováno v: Sens Actuators B Chem

Bacterial infections are one of the major causes of death worldwide. The identification of a bacterial species that is the source of an infection generally takes a long time, and often exceeds the treatment window for seriously ill patients. Many of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63d05c001d17a071daaf6d30a03367c
https://pubmed.ncbi.nlm.nih.gov/34483482

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Coherent confocal light scattering spectroscopic microscopy evaluates cancer progression and aggressiveness in live cells and tissue

Autor: Maria Glyavina, Douglas K. Pleskow, Lei Zhang, Le Qiu, Lev T. Perelman, Irving Itzkan, Conor J. Sheil, Shweta Shinagare, Mark F. Coughlan, Edward Vitkin, Vladimir Turzhitsky, Yuri Zakharov, Umar Khan, Liming Chen, Xuejun Zhang

Publikováno v: ACS Photonics

The observation of biological structures in live cells beyond the diffraction limit with super-resolution fluorescence microscopy is limited by the ability of fluorescence probes to permeate live cells and the effect of these probes, which are often

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23683b5dd62849ef6f3c738c03429068
https://europepmc.org/articles/PMC8411902/

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Spectroscopic label-free microscopy of changes in live cell chromatin and biochemical composition in transplantable organoids

Autor: Yuri Zakharov, Lev T. Perelman, Giuseppe Pettinato, Paul Kumar Upputuri, Robert A. Fisher, Umar Khan, Irving Itzkan, Liming Chen, Lei Zhang, Conor J. Sheil, Maria Glyavina, Mark F. Coughlan, Edward Vitkin, Le Qiu, Xuejun Zhang, Antonino B. D'Assoro

Publikováno v: Science Advances

Formation of transplantable reproducible hiPSC organoids can be aided with real-time label-free intracellular spectroscopy.
Organoids formed from human induced pluripotent stem cells (hiPSCs) could be a limitless source of functional tissue for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382cd0f0b2f66b64ef40f1d7aa8a1612
https://pubmed.ncbi.nlm.nih.gov/34407934

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Two-photon polymerization nanofabrication of ultracompact light scattering spectroscopic probe for detection of pre-cancer in pancreatic cyst

Autor: Irving Itzkan, Yuri Zakharov, Tyler M. Berzin, Maria Glyavina, Le Qiu, Lev T. Perelman, Conor J. Sheil, Mark F. Coughlan, Jonah Cohen, Douglas K. Pleskow, Umar Khan, Mandeep S. Sawhney, Lei Zhang

Publikováno v: Opt Lasers Eng

Pancreatic cancer has one of the worst survival rates of all major cancers, with pancreatic cystic lesions accounting for one in three pancreatic surgeries. The current gold-standard for diagnosis of pancreatic cyst malignancy is based on the endosco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167b4c8367d464ed21f3b41388769db7
https://europepmc.org/articles/PMC8294208/

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Imaging and spectroscopy with scattered light from the tissue to chromatin scale

Autor: Maria Glyavina, Douglas K. Pleskow, Mark F. Coughlan, Umar Khan, Irving Itzkan, Xuejun Zhang, Le Qiu, Edward Vitkin, Lev T. Perelman, Lei Zhang, Yuri Zakharov

Publikováno v: Multiscale Imaging and Spectroscopy II.

In this talk, we will discuss how scattered light can be used for noninvasive detection of invisible pre-cancer in organs such as the esophagus or pancreas which seem to have little in common. Nevertheless, since pre-cancer in many organs is characte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b5bfd71edbbae33159ed817be137a27
https://doi.org/10.1117/12.2590876

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Multispectral Endoscopy with Light Gating for Early Cancer Detection

Autor: Lev T. Perelman, Lei Zhang, Douglas K. Pleskow, Edward Vitkin, Vladimir Turzhitsky, Irving Itzkan, Kanchan Kantekure, Yuri Zakharov, Umar Khan, Mandeep S. Sawhney, Le Qiu, Jeff Goldsmith, Tyler M. Berzin

Publikováno v: IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society. 25(1)

This paper reports the application of endoscopic light scattering spectroscopy (LSS) with light gating to detect malignancies in the biliary and pancreatic ducts, and also reviews the application of endoscopic LSS for differentiating cystic neoplasms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb320df9c9b7bc8af4c7851e417d7de
https://pubmed.ncbi.nlm.nih.gov/31244520

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Picoanalysis of Drugs in Biofluids with Quantitative Label-Free Surface-Enhanced Raman Spectroscopy

Autor: Vladimir Turzhitsky, Irving Itzkan, Lei Zhang, Lev T. Perelman, Yuri Zakharov, Umar Khan, Gary L. Horowitz, Edward Vitkin, Le Qiu

Publikováno v: Small (Weinheim an der Bergstrasse, Germany). 14(47)

The enormous increase of Raman signal in the vicinity of metal nanoparticles allows surface-enhanced Raman spectroscopy (SERS) to be employed for label-free detection of substances at extremely low concentrations. However, the ultimate potential of l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf01d71e375091f0fe41866af25781f
https://pubmed.ncbi.nlm.nih.gov/30369072

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