Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yuri Yu. Shchegolev"'
Autor:
Yuri Yu. Shchegolev, Danila V. Sorokin, Alexander M. Scherbakov, Olga E. Andreeva, Diana I. Salnikova, Ekaterina I. Mikhaevich, Margarita V. Gudkova, Mikhail A. Krasil’nikov
Publikováno v:
BioImpacts, Vol 13, Iss 4, Pp 313-321 (2023)
Introduction: Resistance to chemotherapy and/or irradiation remains one of the key features of malignant tumors, which largely limits the efficiency of antitumor therapy. In this work, we studied the progression mechanism of breast cancer cell resist
Externí odkaz:
https://doaj.org/article/beb324107022466888a107ab710c0b69
Autor:
Yuri A. Piven, Veronica G. Zinovich, Tatyana S. Khlebnicova, Margarita A. Yastrebova, Anton E. Matous, Danila V. Sorokin, Alexander M. Scherbakov, Yuri Yu. Shchegolev, Fedor A. Lakhvich
Publikováno v:
Organicbiomolecular chemistry. 19(47)
Effective method of synthesis of 8-aryl-4,5-dihydrothiazolo[4',5':3,4]benzo[1,2-c]isoxazol-2-amines was developed. The method includes α-keto bromination of 3-aryl-6,7-dihydrobenzo[c]isoxazol-4(5H)-ones followed by condensation of obtained bromo der
Autor:
Mikhail A. Krasil'nikov, Danila V. Sorokin, Marina V. Nemtsova, Alexander M. Scherbakov, Olga E. Andreeva, Margarita V Gudkova, Yuri Yu. Shchegolev, Ekaterina I Mikhaevich, Irina V. Bure
Publikováno v:
Molecules
Molecules, Vol 26, Iss 6661, p 6661 (2021)
Molecules, Vol 26, Iss 6661, p 6661 (2021)
Hormone therapy is one of the most effective breast cancer treatments, however, its application is limited by the progression of hormonal resistance, both primary or acquired. The development of hormonal resistance is caused either by an irreversible
Autor:
Alexander M. Scherbakov, Mikhail A. Krasil'nikov, Danila V. Sorokin, Marina V. Nemtsova, Ekaterina B. Kuznetsova, Yuri Yu. Shchegolev, Ekaterina I Mikhaevich, Margarita V Gudkova, Olga E. Andreeva, Irina V. Bure, Dmitry V. Bagrov, Dmitry S. Mikhaylenko
Publikováno v:
Molecules, Vol 26, Iss 2499, p 2499 (2021)
Molecules
Molecules
Exosomes are the small vesicles that are secreted by different types of normal and tumour cells and can incorporate and transfer their cargo to the recipient cells. The main goal of the present work was to study the tumour exosomes’ ability to accu
Autor:
Danila V. Sorokin, Alexander M. Scherbakov, Margarita V Gudkova, Yuri Yu. Shchegolev, Oxana Ryabaya, Mikhail A. Krasil'nikov, Lev M. Berstein
Publikováno v:
Pharmaceuticals
Volume 13
Issue 9
Pharmaceuticals, Vol 13, Iss 206, p 206 (2020)
Volume 13
Issue 9
Pharmaceuticals, Vol 13, Iss 206, p 206 (2020)
The phenomenon of the primary or acquired resistance of cancer cells to antitumor drugs is among the key problems of oncology. For breast cancer, the phenomenon of the resistance to hormonal or target therapy may be based on the numerous mechanisms i
Autor:
Aleh P. Savochka, Olga E. Andreeva, Yuri Yu. Shchegolev, Vladimir N. Zhabinskii, Arif R. Mekhtiev, Vladimir A. Khripach, Alexander M. Scherbakov, Dmitrii S. Shcherbinin
Publikováno v:
Chemistry & Biodiversity. 16
Brassinosteroids (BS), a class of plant-specific steroid hormones, are considered as new potential anticancer agents for the treatment of tumors of different origin, including hormone-dependent cancers. Effects of a synthetic brassinosteroid BS4 ((22
Autor:
Yuri Yu. Shchegolev, Mikhail A. Krasil'nikov, Olga E. Andreeva, Danila V. Sorokin, Alexey Shunaev, Margarita V Gudkova, Marina V. Nemtsova, Ekaterina I Mikhaevich, Irina V. Bure, Lev M. Berstein, Alexander M. Scherbakov
Publikováno v:
Chemico-Biological Interactions. 330:109243
mTOR inhibitors are considered today to be one of the most promising anticancer drugs. Here to study the mechanism of the acquired resistance of MCF-7 breast cancer cells to mTOR inhibitors two different models of the cell resistance were used: rapam