Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Yuri Y Shevelyov"'
Autor:
Semen A. Doronin, Artem A. Ilyin, Anna D. Kononkova, Mikhail A. Solovyev, Oxana M. Olenkina, Valentina V. Nenasheva, Elena A. Mikhaleva, Sergey A. Lavrov, Anna Y. Ivannikova, Ruslan A. Simonov, Anna A. Fedotova, Ekaterina E. Khrameeva, Sergey V. Ulianov, Sergey V. Razin, Yuri Y. Shevelyov
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Transport of macromolecules through the nuclear envelope (NE) is mediated by nuclear pore complexes (NPCs) consisting of nucleoporins (Nups). Elys/Mel-28 is the Nup that binds and connects the decondensing chromatin with the reassembled NPCs
Externí odkaz:
https://doaj.org/article/634150327a894b9faa6375a04bf66413
Autor:
Beatrice C Milon, Haibo Cheng, Mikhail V Tselebrovsky, Sergei A Lavrov, Valentina V Nenasheva, Elena A Mikhaleva, Yuri Y Shevelyov, Dmitry I Nurminsky
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49692 (2012)
Theoretical models suggest that gene silencing at the nuclear periphery may involve "closing" of chromatin by transcriptional repressors, such as histone deacetylases (HDACs). Here we provide experimental evidence confirming these predictions. Histon
Externí odkaz:
https://doaj.org/article/824d19c9bf84433a9355c3e9f98ffc59
Autor:
Yuri Y. Shevelyov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15771 (2023)
Heterochromatin and euchromatin form different spatial compartments in the interphase nucleus, with heterochromatin being localized mainly at the nuclear periphery. The mechanisms responsible for peripheral localization of heterochromatin are still n
Externí odkaz:
https://doaj.org/article/bd197b1877ac42d29bfdb0ce82252e9d
Autor:
Sergey V. Ulianov, Vlada V. Zakharova, Aleksandra A. Galitsyna, Pavel I. Kos, Kirill E. Polovnikov, Ilya M. Flyamer, Elena A. Mikhaleva, Ekaterina E. Khrameeva, Diego Germini, Mariya D. Logacheva, Alexey A. Gavrilov, Alexander S. Gorsky, Sergey K. Nechaev, Mikhail S. Gelfand, Yegor S. Vassetzky, Alexander V. Chertovich, Yuri Y. Shevelyov, Sergey V. Razin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Genomes are partitioned into topologically associating domains (TADs). Here the authors present single-nucleus Hi-C maps in Drosophila at 10 kb resolution, demonstrating the presence of chromatin compartments in individual nuclei, and partitioning of
Externí odkaz:
https://doaj.org/article/8dcfb2d70fc24ab89ca4dad46c6324c9
Autor:
Yuri Y. Shevelyov, Sergey V. Ulianov, Mikhail S. Gelfand, Stepan N. Belyakin, Sergey V. Razin
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10976 (2022)
Dosage compensation equalizes gene expression in a single male X chromosome with that in the pairs of autosomes and female X chromosomes. In the fruit fly Drosophila, canonical dosage compensation is implemented by the male-specific lethal (MSL) comp
Externí odkaz:
https://doaj.org/article/ebec647bcbf44d5ca99a6167c846b213
Autor:
Sergey V. Ulianov, Semen A. Doronin, Ekaterina E. Khrameeva, Pavel I. Kos, Artem V. Luzhin, Sergei S. Starikov, Aleksandra A. Galitsyna, Valentina V. Nenasheva, Artem A. Ilyin, Ilya M. Flyamer, Elena A. Mikhaleva, Mariya D. Logacheva, Mikhail S. Gelfand, Alexander V. Chertovich, Alexey A. Gavrilov, Sergey V. Razin, Yuri Y. Shevelyov
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The role of the nuclear lamina (NL) in chromatin architecture is still poorly understood. Here, the authors provide evidence that disruption of the NL in Drosophila cells leads to overall chromatin compaction and repositioning from the nuclear envelo
Externí odkaz:
https://doaj.org/article/019c5aaf61ed41efb63d52b8af38836b
Autor:
Yuri Y. Shevelyov
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9475 (2020)
For a long time, the nuclear lamina was thought to be the sole scaffold for the attachment of chromosomes to the nuclear envelope (NE) in metazoans. However, accumulating evidence indicates that nuclear pore complexes (NPCs) comprised of nucleoporins
Externí odkaz:
https://doaj.org/article/ef876a88b055473384fa14b6ff8cee7d
Autor:
Artem A Ilyin, Anna D Kononkova, Anastasia V Golova, Viktor V Shloma, Oxana M Olenkina, Valentina V Nenasheva, Yuri A Abramov, Alexei A Kotov, Daniil A Maksimov, Petr P Laktionov, Alexey V Pindyurin, Aleksandra A Galitsyna, Sergey V Ulianov, Ekaterina E Khrameeva, Mikhail S Gelfand, Stepan N Belyakin, Sergey V Razin, Yuri Y Shevelyov
Publikováno v:
Nucleic Acids Research. 50:3203-3225
Eukaryotic chromosomes are spatially segregated into topologically associating domains (TADs). Some TADs are attached to the nuclear lamina (NL) through lamina-associated domains (LADs). Here, we identified LADs and TADs at two stages of Drosophila s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8d61c219ec0696570c9a5b76c08a49
https://doi.org/10.1093/nar/gkac109
https://doi.org/10.1093/nar/gkac109
Autor:
Victoria A Kobets, Sergey V Ulianov, Aleksandra A Galitsyna, Semen A Doronin, Elena A Mikhaleva, Mikhail S Gelfand, Yuri Y Shevelyov, Sergey V Razin, Ekaterina E Khrameeva
Publikováno v:
Briefings in Bioinformatics. 24
The chromatin interaction assays, particularly Hi-C, enable detailed studies of genome architecture in multiple organisms and model systems, resulting in a deeper understanding of gene expression regulation mechanisms mediated by epigenetics. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9713dd71c2b304ae46a68e20f55efef3
https://doi.org/10.1093/bib/bbad044
https://doi.org/10.1093/bib/bbad044
Autor:
Yuri Y, Shevelyov, Sergey V, Ulianov, Mikhail S, Gelfand, Stepan N, Belyakin, Sergey V, Razin
Publikováno v:
International journal of molecular sciences. 23(18)
Dosage compensation equalizes gene expression in a single male X chromosome with that in the pairs of autosomes and female X chromosomes. In the fruit fly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbeab4eb62721aef26b2bb06fb189f3b
https://pubmed.ncbi.nlm.nih.gov/36142884
https://pubmed.ncbi.nlm.nih.gov/36142884