Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yuri V. Kravatsky"'
Publikováno v:
Biology, Vol 11, Iss 10, p 1422 (2022)
In this paper, we describe a method for the study of colocalization effects between stretch–stretch and stretch–point genome tracks based on a set of indices varying within the (–1, +1) interval. The indices combine the distances between the ce
Externí odkaz:
https://doaj.org/article/82a3450b6033463389f2d6ca11f1249c
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The regulation of gene expression has been studied for decades, but the underlying mechanisms are still not fully understood. As well as local and distant regulation, there are specific mechanisms of regulation during development and physiological mo
Externí odkaz:
https://doaj.org/article/1a1c32b6c7c3459b8c3eeb0326aa89e7
Autor:
Olga V. Kretova, Daria M. Fedoseeva, Maria A. Gorbacheva, Natalya M. Gashnikova, Maria P. Gashnikova, Nataliya V. Melnikova, Vladimir R. Chechetkin, Yuri V. Kravatsky, Nickolai A. Tchurikov
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 8, Iss , Pp 330-344 (2017)
RNAi has been suggested for use in gene therapy of HIV/AIDS, but the main problem is that HIV-1 is highly variable and could escape attack from the small interfering RNAs (siRNAs) due to even single nucleotide substitutions in the potential targets.
Externí odkaz:
https://doaj.org/article/108faf74656441c38a4a0d298be93785
Autor:
Nickolai A. Tchurikov, Elena S. Klushevskaya, Daria M. Fedoseeva, Ildar R. Alembekov, Galina I. Kravatskaya, Vladimir R. Chechetkin, Yuri V. Kravatsky, Olga V. Kretova
Publikováno v:
Cells, Vol 9, Iss 12, p 2587 (2020)
Chromosomes are organized into 3D structures that are important for the regulation of gene expression and differentiation. Important role in formation of inter-chromosome contacts play rDNA clusters that make up nucleoli. In the course of differentia
Externí odkaz:
https://doaj.org/article/4bb5ee7e87724caf8bc55aab7bfddccf
Autor:
Nickolai A. Tchurikov, Daria M. Fedoseeva, Elena S. Klushevskaya, Ivan Y. Slovohotov, Vladimir R. Chechetkin, Yuri V. Kravatsky, Olga V. Kretova
Publikováno v:
Cells, Vol 8, Iss 11, p 1393 (2019)
Human rDNA clusters form numerous contacts with different chromosomal regions as evidenced by chromosome conformation capture data. Heterochromatization of rDNA genes leads to heterochromatization in different chromosomal regions coupled with the act
Externí odkaz:
https://doaj.org/article/2f9ac5da5ff24e1bacf891ed8f937844
Autor:
Nickolai A. Tchurikov, Ildar R. Alembekov, Elena S. Klushevskaya, Antonina N. Kretova, Ann M. Keremet, Anastasia E. Sidorova, Polina B. Meilakh, Vladimir R. Chechetkin, Galina I. Kravatskaya, Yuri V. Kravatsky
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7201
Double-strand DNA breakes (DSBs) are the most deleterious and widespread examples of DNA damage. They inevitably originate from endogenous mechanisms in the course of transcription, replication, and recombination, as well as from different exogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8091bb578af6923776d7d0e22df18455
https://pubmed.ncbi.nlm.nih.gov/35806206
https://pubmed.ncbi.nlm.nih.gov/35806206
Autor:
G.I. Kravatskaya, E. S. Klushevskaya, Maria A. Lagarkova, Vsevolod Yu. Makeev, L. A. Uroshlev, Yuri V. Kravatsky, Ildar R. Alembekov, Nickolai A. Tchurikov
Publikováno v:
Cancers
Cancers, Vol 13, Iss 3889, p 3889 (2021)
Volume 13
Issue 15
Cancers, Vol 13, Iss 3889, p 3889 (2021)
Volume 13
Issue 15
Simple Summary There are nine DSB hot spots located in the non-transcribed spacer of human rDNA units. Circular chromosome conformation capture data indicate that the rDNA clusters often shape contact with a specific set of chromosomal regions contai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b465aef4150832e2e8d5f2cde2edf999
http://europepmc.org/articles/PMC8345467
http://europepmc.org/articles/PMC8345467
Autor:
Vladimir G. Tumanyan, Sergey A. Lukshin, Yuri V. Kravatsky, A. M. Nikitin, Yury V. Milchevskiy, Vladislava Milchevskaya, Natalia G. Esipova, Ivan V. Filatov
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0239793 (2021)
PLoS ONE, Vol 16, Iss 5, p e0239793 (2021)
MotivationLocal protein structure is usually described via classifying each peptide to a unique element from a set of pre-defined structures. These so-called structural alphabets may differ in the number of structures or the length of peptides. Most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed46a8631bd30da5696824bf47df492
http://europepmc.org/articles/PMC8136669
http://europepmc.org/articles/PMC8136669
Autor:
Nickolai A Tchurikov, Olga V Kretova, Daria M Fedoseeva, Dmitri V Sosin, Sergei A Grachev, Marina V Serebraykova, Svetlana A Romanenko, Nadezhda V Vorobieva, Yuri V Kravatsky
Publikováno v:
PLoS Genetics, Vol 9, Iss 4, p e1003429 (2013)
Genome instability plays a key role in multiple biological processes and diseases, including cancer. Genome-wide mapping of DNA double-strand breaks (DSBs) is important for understanding both chromosomal architecture and specific chromosomal regions
Externí odkaz:
https://doaj.org/article/f8542f42a0f54207b33b8730930a5c1d
Autor:
D. M. Fedoseeva, Nataliya V. Melnikova, Maria A. Gorbacheva, Yuri V. Kravatsky, V. R. Chechetkin, Maria P. Gashnikova, Olga V. Kretova, Natalya M. Gashnikova, Nickolai A. Tchurikov
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 8, Iss, Pp 330-344 (2017)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
RNAi has been suggested for use in gene therapy of HIV/AIDS, but the main problem is that HIV-1 is highly variable and could escape attack from the small interfering RNAs (siRNAs) due to even single nucleotide substitutions in the potential targets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f771ded70583ccf64ba886ac3b33c16
http://www.sciencedirect.com/science/article/pii/S2162253117302202
http://www.sciencedirect.com/science/article/pii/S2162253117302202