Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis

Autor: Yukinari Haraoka, Yuki Akieda, Yuri Nagai, Chihiro Mogi, Tohru Ishitani

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

It is unclear how a single oncogenic cell primes tumorigenesis. Here the authors visualised this behaviour using a zebrafish larval skin as a model and show that RasG12V oncogenic cell is eliminated through oncogene-senescence while a gain of functio

Externí odkaz: https://doaj.org/article/c9be9250be8d47abbb6730e2f4974c7e

Textured soy protein, collagen and maltodextrin as extenders to improve the physicochemical and sensory properties of beef burger

Autor: Andrea Carla da Silva Barretto, Letícia Yuri Nagai, Talita Maira Goss Milani, Natália Righetti Rocha Trinca, Gisandro Reis de Carvalho

Publikováno v: Food Science and Technology, Issue: ahead, Published: 26 OCT 2017
Food Science and Technology v.37 suppl.1 2017
Food Science and Technology (Campinas)
Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)
instacron:SBCTA
Food Science and Technology, Iss 0 (2017)
Food Science and Technology, Volume: 37 Supplement 1, Pages: 10-16, Published: 26 OCT 2017
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc64ce4c8310ab9230dc6969f9c91e1a
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612017005026123&lng=en&tlng=en

Karyopherin-Mediated Nuclear Import of the Homing Endonuclease VMA1-Derived Endonuclease Is Required for Self-Propagation of the Coding Region

Autor: Satoru Nogami, Yoshikazu Ohya, Yuri Nagai, Fumi Kumagai-Sano

Publikováno v: Molecular and Cellular Biology. 23:1726-1736

VMA1-derived endonuclease (VDE), a site-specific endonuclease in Saccharomyces cerevisiae, enters the nucleus to generate a double-strand break in the VDE-negative allelic locus, mediating the self-propagating gene conversion called homing. Although

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc97e1ea5d5e95f1cd430231d42bc1f9
https://doi.org/10.1128/mcb.23.5.1726-1736.2003

Amino Acid Production:L-Lysine

Autor: Hisao Ito, Hisashi Yasueda, Yuri Nagai

Publikováno v: Encyclopedia of Industrial Biotechnology

l-Lysine is an essential amino acid for humans and animals and is exclusively used as a feed additive for swine and poultry throughout the world, since most grains used for the feed are deficient in l-lysine in nutritional amino acid balance. This am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0dbf236fb24a2fc0037f69463d52dcf9
https://doi.org/10.1002/9780470054581.eib022

Molecular mechanism of vde-initiated intein homing in yeast nuclear genome

Autor: Yuri Nagai, Yoshikazu Ohya, Tomoyuki Fukuda

Publikováno v: Advances in biophysics. 38

Summary In Saccharomyces cerevisiae, VMAI intein encodes a homing endonuclease termed VDE which is produced by an autocatalytic protein splicing reaction. VDE introduces a DSB at its recognition sequence on intein-minus allele, resulting in the later

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16b57629f760c1f2996070dccd86c0c6
https://pubmed.ncbi.nlm.nih.gov/15476900