Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yuri Kobzev"'
Autor:
Sabah Kadri, Jimmy Lee, Carrie Fitzpatrick, Natalie Galanina, Madina Sukhanova, Girish Venkataraman, Shruti Sharma, Brad Long, Kristin Petras, Megan Theissen, Mei Ming, Yuri Kobzev, Wenjun Kang, Ailin Guo, Weige Wang, Nifang Niu, Howard Weiner, Michael Thirman, Wendy Stock, Sonali M. Smith, Chadi Nabhan, Jeremy P. Segal, Pin Lu, Y. Lynn Wang
Publikováno v:
Blood Advances, Vol 1, Iss 12, Pp 715-727 (2017)
Abstract: Ibrutinib has generated remarkable responses in patients with chronic lymphocytic leukemia (CLL), including those with an unfavorable cytogenetic profile. However, patients develop resistance, with poor outcomes and no established treatment
Externí odkaz:
https://doaj.org/article/637796cbfd31417ebb804451e9532aa2
Autor:
Jeremy P. Segal, Girish Venkataraman, Ailin Guo, Pin Lu, Kristin Petras, Y. Lynn Wang, Yuri Kobzev, Wenjun Kang, Weige Wang, Sonali M. Smith, Michael J. Thirman, Wendy Stock, Shruti Sharma, Natalie Galanina, Chadi Nabhan, Carrie Fitzpatrick, Howard L. Weiner, Madina Sukhanova, Sabah Kadri, Jimmy Lee, Nifang Niu, Megan Theissen, Brad Long, Mei Ming
Publikováno v:
Blood Advances. 1:715-727
Ibrutinib has generated remarkable responses in patients with chronic lymphocytic leukemia (CLL), including those with an unfavorable cytogenetic profile. However, patients develop resistance, with poor outcomes and no established treatment options.
Publikováno v:
Genes, Chromosomes and Cancer. 41:339-352
The NUP98 gene has been reported to be fused with at least 15 partner genes in leukemias with 11p15 translocations. We report the results of screening of cases with cytogenetically documented rearrangements of 11p15 and the subsequent identification
Autor:
Yuri Kobzev, Anna G. Turkina, Adel’ Zakharova, Domracheva Ev, Nina Khoroshko, Gordon W. Dewald
Publikováno v:
Cancer Genetics and Cytogenetics. 106:128-134
We used two-color fluorescence in situ hybridization (FISH) to detect BCR/ABL fusion in interphase nuclei in bone marrow of 17 patients with chronic myeloid leukemia (CML) before and in the course of interferon therapy. The results of FISH were compa
Autor:
Girish Venkataraman, Y. Lynn Wang, Weige V Wang, Bradley C. Long, Natalie Galanina, Shruti Sharma, Pin Lu, Megan Theissen, Howie Lawrence Weiner, Ailin Guo, Nifang Niu, Michael J. Thirman, Sabah Kadri, Carrie Fitzpatrick, Jimmy Lee, Madina Sukhanova, Jeremy P. Segal, Kang Wenjun, Mei Ming, Yuri Kobzev, Sonali M. Smith
Publikováno v:
Blood. 128:3961-3961
Introduction Ibrutinib (ibr), a first-in-class BTK inhibitor, has high response rates in both relapsed/refractory and treatment naïve chronic lymphocytic leukemia (CLL) independent of high-risk FISH abnormalities (NEJM. 2015; 373:2425-37, NEJM. 2013