Zobrazeno 1 - 3
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pro vyhledávání: '"Yuri Genda"'
Publikováno v:
The Journal of Toxicological Sciences. 23:561-574
Thirteen-week oral repeated dose toxicity of ecabapide, a gastroprokinetic drug, was investigated in dogs at dosage levels of 50, 175 or 600 mg/kg, and in rats at dosage levels of 25, 100, 400 or 1600 mg/kg. In dogs, vomiting, aqueous salivation, bod
Autor:
Hisashi Yamamura, Kazuhisa Furuhama, Nami Ishijima, Hiroshi Ohno, Yuri Genda, Yuji Takahashi, Koji Kakihata, Mamoru Nomura
Publikováno v:
The Journal of Toxicological Sciences. 20:47-66
The single-dose intravenous toxicities of iodixanol, a new nonionic iso-osmolar contrast medium, were investigated in mice, rats and monkeys. The LD50 values were estimated to be 17.9 gI/kg for male mice and 16.2 gI/kg for female mice, 18.8 gI/kg for
Publikováno v:
The Journal of toxicological sciences. 20
Groups of 3 male and 3 female wild-caught cynomolgus monkeys were given iodixanol, a radiographic contrast medium, by intravenous injection at dosage levels of 100, 300 or 1,000 mgI/kg/day for four weeks to evaluate its toxicity. An extra 2 animals o