Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Yuri B Schwartz"'
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004495 (2014)
Polycomb Group (PcG) proteins are epigenetic repressors that control metazoan development and cell differentiation. In Drosophila, PcG proteins form five distinct complexes targeted to genes by Polycomb Response Elements (PREs). Of all PcG complexes
Externí odkaz:
https://doaj.org/article/c79d9a1be2534a3db2c5ad899bdbe10b
Autor:
Nicole C Riddle, Youngsook L Jung, Tingting Gu, Artyom A Alekseyenko, Dalal Asker, Hongxing Gui, Peter V Kharchenko, Aki Minoda, Annette Plachetka, Yuri B Schwartz, Michael Y Tolstorukov, Mitzi I Kuroda, Vincenzo Pirrotta, Gary H Karpen, Peter J Park, Sarah C R Elgin
Publikováno v:
PLoS Genetics, Vol 8, Iss 9, p e1002954 (2012)
Chromatin environments differ greatly within a eukaryotic genome, depending on expression state, chromosomal location, and nuclear position. In genomic regions characterized by high repeat content and high gene density, chromatin structure must silen
Externí odkaz:
https://doaj.org/article/2fa17e0806bd424bb998a29c43376d5e
Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context.
Autor:
Artyom A Alekseyenko, Joshua W K Ho, Shouyong Peng, Marnie Gelbart, Michael Y Tolstorukov, Annette Plachetka, Peter V Kharchenko, Youngsook L Jung, Andrey A Gorchakov, Erica Larschan, Tingting Gu, Aki Minoda, Nicole C Riddle, Yuri B Schwartz, Sarah C R Elgin, Gary H Karpen, Vincenzo Pirrotta, Mitzi I Kuroda, Peter J Park
Publikováno v:
PLoS Genetics, Vol 8, Iss 4, p e1002646 (2012)
The Drosophila MSL complex mediates dosage compensation by increasing transcription of the single X chromosome in males approximately two-fold. This is accomplished through recognition of the X chromosome and subsequent acetylation of histone H4K16 o
Externí odkaz:
https://doaj.org/article/054e3f5a16c34030bd847773adcbd60f
Autor:
Yuri B Schwartz, Tatyana G Kahn, Per Stenberg, Katsuhito Ohno, Richard Bourgon, Vincenzo Pirrotta
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000805 (2010)
Polycomb (PcG) regulation has been thought to produce stable long-term gene silencing. Genomic analyses in Drosophila and mammals, however, have shown that it targets many genes, which can switch state during development. Genetic evidence indicates t
Externí odkaz:
https://doaj.org/article/4f8d22b8028d49d69d1c2048091b9280
Autor:
Cheri A Schaaf, Ziva Misulovin, Gurmukh Sahota, Akbar M Siddiqui, Yuri B Schwartz, Tatyana G Kahn, Vincenzo Pirrotta, Maria Gause, Dale Dorsett
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6202 (2009)
The cohesin protein complex was first recognized for holding sister chromatids together and ensuring proper chromosome segregation. Cohesin also regulates gene expression, but the mechanisms are unknown. Cohesin associates preferentially with active
Externí odkaz:
https://doaj.org/article/199cb84bcf8944dbb1f2cbbd80bbbd81
Development of multicellular animals requires epigenetic repression by Polycomb group proteins. The latter assemble in multi-subunit complexes, of which two kinds, Polycomb Repressive Complex 1 (PRC1) and Polycomb Repressive Complex 2 (PRC2), act tog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6db0eaf97a64dfedf2fa8c2adc6affa
https://doi.org/10.1101/2023.01.12.523763
https://doi.org/10.1101/2023.01.12.523763
Methylation of lysine 36 on histone H3 is required to control transposon activities in somatic cells
Transposable elements constitute a substantial portion of most eukaryotic genomes and their activity can lead to developmental and neuronal defects. In the germline, transposon activity is antagonized by the PIWI-interacting RNA pathway tasked with r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e946fd7a7254659f83487acf7842243
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-201601
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-201601
Autor:
Tatyana G. Kahn, Mikhail Savitsky, Chikuan Kuong, Caroline Jacquier, Giacomo Cavalli, Jia-Ming Chang, Yuri B. Schwartz
Drosophila insulators were the first DNA elements found to regulate gene expression by delimiting chromatin contacts. We still do not know how many of them exist and what impact they have on the Drosophila genome folding. Contrary to vertebrates, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8805abe315c9056bdff3781b7069084
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-204742
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-204742
Autor:
Hyuckjoon Kang, Janel R. Cabrera, Barry M. Zee, Heather A. Kang, Jenny Marie Jobe, Maeve B. Hegarty, Aurelie E. Barry, Alexander Glotov, Yuri B. Schwartz, Mitzi I. Kuroda
Publikováno v:
Science Advances. 8
Polycomb group (PcG) mutants were first identified in Drosophila on the basis of their failure to maintain proper Hox gene repression during development. The proteins encoded by the corresponding fly genes mainly assemble into one of two discrete Pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb1affeebcace7d46bb6700a421f9d8
https://doi.org/10.1126/sciadv.add0103
https://doi.org/10.1126/sciadv.add0103
Autor:
Tatyana G. Kahn, Mikhail Savitsky, Chikuan Kuong, Caroline Jacquer, Giacomo Cavalli, Jia-Ming Chang, Yuri B. Schwartz
Drosophila insulators were the first DNA elements discovered to regulate gene expression by delimiting chromatin contacts. Remarkably, it is still unclear how many of them exist in the Drosophila genome and whether they have a pervasive impact on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba9b8f03725e2a816568564151252ab5
https://doi.org/10.1101/2022.07.18.500462
https://doi.org/10.1101/2022.07.18.500462