Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Yuri B, Porozov"'
Autor:
Andrey V. Khramchikhin, Mariya A. Skryl’nikova, Maxim A. Gureev, Vladimir V. Zarubaev, Iana L. Esaulkova, Polina A. Ilyina, Oussama Abdelhamid Mammeri, Dar’ya V. Spiridonova, Yuri B. Porozov, Vladimir A. Ostrovskii
Publikováno v:
Molecules, Vol 28, Iss 21, p 7427 (2023)
A novel method for synthesizing 1,2,4-triazole- and tetrazole-containing 4H-thiopyrano[2,3-b]quinolines using a new combination of the thio-Michael and aza-Morita–Baylis–Hillman reactions was developed. Target compounds were evaluated for their c
Externí odkaz:
https://doaj.org/article/9eaf67032beb471589bde340bd8a037b
Autor:
José A. Gavira, Miriam Rico-Jiménez, Álvaro Ortega, Natalia V. Petukhova, Dmitrii S. Bug, Albert Castellví, Yuri B. Porozov, Igor B. Zhulin, Tino Krell, Miguel A. Matilla
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Bacteria have evolved a sophisticated array of signal transduction systems that allow them to adapt their physiology and metabolism to changing environmental conditions. Typically, these systems recognize signals through dedicated ligand bin
Externí odkaz:
https://doaj.org/article/130fca54d3ab475593cff69bb7378c07
Autor:
Yaroslav V. Solovev, Anna A. Igolkina, Pavel O. Kuliaev, Anton S. Sulima, Vladimir A. Zhukov, Yuri B. Porozov, Evgeny A. Pidko, Evgeny E. Andronov
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
The difference in symbiotic specificity between peas of Afghanistan and European phenotypes was investigated using molecular modeling. Considering segregating amino acid polymorphism, we examined interactions of pea LykX-Sym10 receptor heterodimers w
Externí odkaz:
https://doaj.org/article/a09d1be37e804a7b941d10098338b185
Autor:
Nadezhda S. Dyrkheeva, Irina A. Chernyshova, Georgy A. Ivanov, Yuri B. Porozov, Anastasia A. Zenchenko, Vladimir E. Oslovsky, Alexandra L. Zakharenko, Darina I. Nasyrova, Galina N. Likhatskaya, Sergey N. Mikhailov, Olga I. Lavrik, Mikhail S. Drenichev
Publikováno v:
Molecules, Vol 27, Iss 8, p 2433 (2022)
Inhibition of human DNA repair enzyme tyrosyl-DNA phosphodiesterase 1 (Tdp1) by different chiral lipophilic nucleoside derivatives was studied. New Tdp1 inhibitors were found in the series of the studied compounds with IC50 = 2.7–6.7 μM. It was sh
Externí odkaz:
https://doaj.org/article/4ad1798b71a34c53a6fa87310fc3e4c9
Autor:
Ivan O. Maslov, Tatiana V. Zinevich, Olga G. Kirichenko, Mikhail V. Trukhan, Sergey V. Shorshnev, Natalya O. Tuaeva, Maxim A. Gureev, Amelia D. Dahlén, Yuri B. Porozov, Helgi B. Schiöth, Vladimir M. Trukhan
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 273 (2022)
Compounds that contain (R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid substituted with bicyclic amino moiety (2-aza-bicyclo[2.2.1]heptane) were designed using molecular modelling methods, synthesised, and found to be potent DPP-4 (dipeptidyl pept
Externí odkaz:
https://doaj.org/article/eb8f6f6ae0d9464ea7a070f9095c60ed
Publikováno v:
Cells, Vol 10, Iss 9, p 2357 (2021)
Myelodysplastic syndrome (MDS) refers to a heterogeneous group of closely related clonal hematopoietic disorders, which are characterized by accumulation of somatic mutations. The acquired mutation burden is suggested to define the pathway and conseq
Externí odkaz:
https://doaj.org/article/5cef63c545ec4c59a1a4445c3454ca46
Autor:
Daria S. Ostroverkhova, Junda Hu, Vadim V. Tarasov, Tatiana I. Melnikova, Yuri B. Porozov, Kerim Mutig
Publikováno v:
Cells, Vol 9, Iss 7, p 1644 (2020)
The kidney is essential for systemic calcium homeostasis. Urinary calcium excretion can be viewed as an integrative renal response to endocrine and local stimuli. The extracellular calcium-sensing receptor (CaSR) elicits a number of adaptive reaction
Externí odkaz:
https://doaj.org/article/039bb224bdfc43309174953b910489f8
Autor:
Natalia O. Tuaeva, Luca Falzone, Yuri B. Porozov, Alexander E. Nosyrev, Vladimir M. Trukhan, Leda Kovatsi, Demetrios A. Spandidos, Nikolaos Drakoulis, Alexandra Kalogeraki, Charalampos Mamoulakis, George Tzanakakis, Massimo Libra, Aristides Tsatsakis
Publikováno v:
Cells, Vol 8, Iss 10, p 1251 (2019)
In recent years, the introduction of new molecular techniques in experimental and clinical settings has allowed researchers and clinicians to propose circulating-tumor DNA (ctDNA) analysis and liquid biopsy as novel promising strategies for the early
Externí odkaz:
https://doaj.org/article/0bcc3d4e1d38420f82a3892f014b9984
Autor:
Maria A. Konkina, Mikhail S. Drenichev, Darina I. Nasyrova, Yuri B. Porozov, Cyril S. Alexeev
Publikováno v:
Sustainable Chemistry and Pharmacy. 32:101011
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6038b37d945ae07b22465e3489546a0c
https://doi.org/10.1016/j.scp.2023.101011
https://doi.org/10.1016/j.scp.2023.101011
Can Modern Molecular Modeling Methods Help Find the Area of Potential Vulnerability of Flaviviruses?
Autor:
Daniil V. Shanshin, Sophia S. Borisevich, Alexander A. Bondar, Yuri B. Porozov, Elena A. Rukhlova, Elena V. Protopopova, Nikita D. Ushkalenko, Valery B. Loktev, Andrei I. Chapoval, Alexander A. Ilyichev, Dmitriy N. Shcherbakov
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7721
Flaviviruses are single-stranded RNA viruses that have emerged in recent decades and infect up to 400 million people annually, causing a variety of potentially severe pathophysiological processes including hepatitis, encephalitis, hemorrhagic fever,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8336d1cd0ba2badc9ba4f6c73491db24
https://pubmed.ncbi.nlm.nih.gov/35887069
https://pubmed.ncbi.nlm.nih.gov/35887069