Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Yuri Mackeyev"'
Publikováno v:
Cancer Nanotechnology, Vol 15, Iss 1, Pp 1-44 (2024)
Abstract Owing to unique facets, such as large surface area, tunable synthesis parameters, and ease of functionalization, mesoporous silica nanoparticles (MSNs) have transpired as a worthwhile platform for cancer theranostics over the last decade. Th
Externí odkaz:
https://doaj.org/article/03fbd39c59cc4fe7ab0ed4e27a3c3dd3
Autor:
Nolan Jackson, Iona Hill, Abdulaziz Alhussan, Kyle Bromma, Jessica Morgan, Belal Abousaida, Yasmin Zahra, Yuri Mackeyev, Wayne Beckham, Steven Herchko, Sunil Krishnan, Devika Basnagge Chithrani
Publikováno v:
Cancer Nanotechnology, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Background Radiotherapy (RT) is an essential component in the treatment regimens for many cancer patients. However, the dose escalation required to improve curative results is hindered due to the normal tissue toxicity that is induced. The i
Externí odkaz:
https://doaj.org/article/6ce8b63f7600436ba73912bcded292c8
Publikováno v:
Cancer Nanotechnology, Vol 14, Iss 1, Pp 1-36 (2023)
Abstract In the last three decades, radiopharmaceuticals have proven their effectiveness for cancer diagnosis and therapy. In parallel, the advances in nanotechnology have fueled a plethora of applications in biology and medicine. A convergence of th
Externí odkaz:
https://doaj.org/article/564c0924427a4830a34bc2f716e3fde1
Publikováno v:
Cells, Vol 12, Iss 10, p 1398 (2023)
BNCT is a high-linear-energy transfer therapy that facilitates tumor-directed radiation delivery while largely sparing adjacent normal tissues through the biological targeting of boron compounds to tumor cells. Tumor-specific accumulation of boron wi
Externí odkaz:
https://doaj.org/article/9d9ad6bbe5bb4a559e60b8ad4e6cdf2d
Autor:
Kshama Gupta, Jeremy C. Jones, Virginea De Araujo Farias, Yuri Mackeyev, Pankaj K. Singh, Alfredo Quiñones-Hinojosa, Sunil Krishnan
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Treatment resistance is observed in all advanced cancers. Colorectal cancer (CRC) presenting as colorectal adenocarcinoma (COAD) is the second leading cause of cancer deaths worldwide. Multimodality treatment includes surgery, chemotherapy, and targe
Externí odkaz:
https://doaj.org/article/75aadf8a35cb41f493571f2ffcf4e454
Autor:
Sanjeev Shukla, Steven Fletcher, Jay Chauhan, Victor Chalfant, Carlos Riveros, Yuri Mackeyev, Pankaj Kumar Singh, Sunil Krishnan, Teruko Osumi, K. C. Balaji
Publikováno v:
Cancer Gene Therapy. 29:1550-1557
The proto-oncogene cellular myelocytomatosis (c-Myc) is a transcription factor that is upregulated in several human cancers. Therapeutic targeting of c-Myc remains a challenge because of a disordered protein tertiary structure. The basic helical stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780ee9bbe54c2e276044c00f7934866c
https://doi.org/10.1038/s41417-022-00455-4
https://doi.org/10.1038/s41417-022-00455-4
Autor:
Pradipta Ranjan Rauta, Yuri Mackeyev, Keith Sanders, Joseph B.K. Kim, Valeria V. Gonzalez, Yasmin Zahra, Muhammad A. Shohayeb, Belal Abousaida, Geraldine V. Vijay, Okan Tezcan, Paul Derry, Anton V. Liopo, Eugene R. Zubarev, Rickey Carter, Pankaj Singh, Sunil Krishnan
Publikováno v:
Science advances. 8(45)
Coating nanoparticles with stealth epilayers increases circulation time by evading opsonization, macrophage phagocytosis, and reticuloendothelial sequestration. However, this also reduces internalization by cancer cells upon reaching the tumor. We de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee89ab0619fef88fec701fbf0650d6b
https://pubmed.ncbi.nlm.nih.gov/36367938
https://pubmed.ncbi.nlm.nih.gov/36367938
Publikováno v:
Nanoscale
CXC chemokine receptor 4 (CXCR4) is overexpressed on most breast cancer cell surfaces including triple negative breast cancer (TNBC) which lacks traditional receptor overexpression. We targeted gold nanoparticles (GNPs) to this receptor via conjugati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b44cc6e1b0a3971b5ba13a8274d7a7f
https://doi.org/10.1039/d1nr05385j
https://doi.org/10.1039/d1nr05385j
Autor:
Subhiksha Raghuram, Yuri Mackeyev, Jessica Symons, Yasmin Zahra, Valeria Gonzalez, Krishnan K. Mahadevan, Katherinne I. Requejo, Anton Liopo, Paul Derry, Eugene Zubarev, Onur Sahin, Joseph Byung-Kyu Kim, Pankaj K. Singh, Sang Hyun Cho, Sunil Krishnan
Publikováno v:
Biomaterials. 291
Major impediments to conveyance of intravenously administered drugs to tumors are biofouling, opsonization, and rapid clearance from the circulation by macrophages and reticuloendothelial phagocytes. Cloaking nanoparticles with stealth epilayers part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2bb68bacb0bdec226379cf8103dc8d
https://pubmed.ncbi.nlm.nih.gov/36368139
https://pubmed.ncbi.nlm.nih.gov/36368139
Autor:
Ajay Singh, Parham Rohani, Paras N. Prasad, Supriya D. Mahajan, Sunil Krishnan, Yuri Mackeyev, B.K. Kim, Mark T. Swihart
Publikováno v:
Journal of Biomedical Nanotechnology. 15:1714-1723
In this study, we have synthesized and characterized a pure boron nanoparticle containing asolectin phospholipid-based liposome construct prepared using a water-in-oil emulsion method, as a novel alternative agent for BNCT, which contain poly(maleic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71407fddf1a919fab39abdc5d8a1ef4
https://doi.org/10.1166/jbn.2019.2800
https://doi.org/10.1166/jbn.2019.2800