Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yuri, Kuryshev"'
Autor:
Annie Delaunois, Matthew Abernathy, Warren D. Anderson, Kylie A. Beattie, Khuram W. Chaudhary, Julie Coulot, Vitalina Gryshkova, Simon Hebeisen, Mark Holbrook, James Kramer, Yuri Kuryshev, Derek Leishman, Isabel Lushbough, Elisa Passini, Will S. Redfern, Blanca Rodriguez, Eric I. Rossman, Cristian Trovato, Caiyun Wu, Jean‐Pierre Valentin
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 3, Pp 1133-1146 (2021)
Abstract We applied a set of in silico and in vitro assays, compliant with the Comprehensive In Vitro Proarrhythmia Assay (CiPA) paradigm, to assess the risk of chloroquine (CLQ) or hydroxychloroquine (OH‐CLQ)‐mediated QT prolongation and Torsade
Externí odkaz:
https://doaj.org/article/d703d6568c29415c8e2d93ccf47af5d0
Publikováno v:
Novartis Foundation symposium. 266
Mutations in the cardiac potassium channel hERG/IKr cause inherited long QT syndrome with increased susceptibility to ventricular arrhythmias. Several mutations in hERG produce trafficking-deficient channels that are retained in the endoplasmic retic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ffaae9b3bb298466e4d4998b0e1d6555
https://pubmed.ncbi.nlm.nih.gov/16050262
https://pubmed.ncbi.nlm.nih.gov/16050262