Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Yuqiong Liang"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Chromatin conformation reorganization is emerging as an important layer of regulation for gene expression and lineage specification. Yet, how lineage-specific transcription factors contribute to the establishment of cell type-specific 3D chr
Externí odkaz:
https://doaj.org/article/cbae918c0dab4d61b4ca7ac0bf4ad59f
Publikováno v:
Cells, Vol 12, Iss 7, p 1050 (2023)
Ferroptosis is an oxidative damage-related, iron-dependent regulated cell death with intracellular lipid peroxide accumulation, which is associated with many physiological and pathological processes. It exhibits unique features that are morphological
Externí odkaz:
https://doaj.org/article/4feeb9cefe9545dd8067ff1e43d8cb6e
Autor:
Tsubasa Munakata, Yuqiong Liang, Seungtaek Kim, David R McGivern, Jon Huibregtse, Akio Nomoto, Stanley M Lemon
Publikováno v:
PLoS Pathogens, Vol 3, Iss 9, Pp 1335-1347 (2007)
Hepatitis C virus (HCV) is a positive-strand RNA virus that frequently causes persistent infections and is uniquely associated with the development of hepatocellular carcinoma. While the mechanism(s) by which the virus promotes cancer are poorly defi
Externí odkaz:
https://doaj.org/article/0568ef9e704b4989a0d3db167ecb1237
Autor:
Lin Qu, Zongdi Feng, Daisuke Yamane, Yuqiong Liang, Robert E Lanford, Kui Li, Stanley M Lemon
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002169 (2011)
Toll-like receptor 3 (TLR3) and cytosolic RIG-I-like helicases (RIG-I and MDA5) sense viral RNAs and activate innate immune signaling pathways that induce expression of interferon (IFN) through specific adaptor proteins, TIR domain-containing adaptor
Externí odkaz:
https://doaj.org/article/0886fd9964fd47d8940d6bcad2ee6f7b
Autor:
Hongkui Zeng, Kyoji Horie, Linda Madisen, Maria N Pavlova, Galina Gragerova, Alex D Rohde, Brian A Schimpf, Yuqiong Liang, Ethan Ojala, Farah Kramer, Patricia Roth, Olga Slobodskaya, Io Dolka, Eileen A Southon, Lino Tessarollo, Karin E Bornfeldt, Alexander Gragerov, George N Pavlakis, George A Gaitanaris
Publikováno v:
PLoS Genetics, Vol 4, Iss 5, p e1000069 (2008)
Inducible and reversible regulation of gene expression is a powerful approach for uncovering gene function. We have established a general method to efficiently produce reversible and inducible gene knockout and rescue in mice. In this system, which w
Externí odkaz:
https://doaj.org/article/d20796b8c63140f2a6de21e85453e4cc
Autor:
Sagar P. Bapat, Caroline Whitty, Cody T. Mowery, Yuqiong Liang, Arum Yoo, Zewen Jiang, Michael C. Peters, Ling-juan Zhang, Ian Vogel, Carmen Zhou, Vinh Q. Nguyen, Zhongmei Li, Christina Chang, Wandi S. Zhu, Annette T. Hastie, Helen He, Xin Ren, Wenli Qiu, Sarah G. Gayer, Chang Liu, Eun Jung Choi, Marlys Fassett, Jarish N. Cohen, Jamie L. Sturgill, Laura E. Crotty Alexander, Jae Myoung Suh, Christopher Liddle, Annette R. Atkins, Ruth T. Yu, Michael Downes, Sihao Liu, Barbara S. Nikolajczyk, In-Kyu Lee, Emma Guttman-Yassky, K. Mark Ansel, Prescott G. Woodruff, John V. Fahy, Dean Sheppard, Richard L. Gallo, Chun Jimmie Ye, Ronald M. Evans, Ye Zheng, Alexander Marson
Publikováno v:
Nature, vol 604, iss 7905
Decades of work have elucidated cytokine signalling and transcriptional pathways that control T cell differentiation and haveled the way to targeted biologic therapies that are effective in a range of autoimmune, allergic and inflammatory diseases. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2437f4952bbe1f222362a7c14dbf448
https://escholarship.org/uc/item/2bv4q0k3
https://escholarship.org/uc/item/2bv4q0k3
Publikováno v:
Nat Immunol
Maintenance of tissue homeostasis is dependent on the communication between stem cells and supporting cells in the same niche. Regulatory T cells (Treg) are a critical component of the stem cell niche to support their differentiation. How Treg cells
Autor:
Yuqiong Liang, Michael Downes, Theodore M. Kamenecka, Ruth T. Yu, Annette R. Atkins, Ye Zheng, Ronald M. Evans, Thomas P. Burris, Chin-San Loo, Laura A. Solt, Sagar P Bapat, Mathias Leblanc, Han Cho, Christina L. Chang, Xuan Zhao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Th17 cells are a subset of T cells that produce interleukin 17 and other proinflammatory cytokines. They are involved in the development of autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. Previous studies illustr
Publikováno v:
The Journal of Immunology. 208:167.10-167.10
The maintenance of tissue homeostasis in steady state or under stress is dependent on the proper communication between the stem cells and the supporting cells in their microenvironment or “niche”. In addition to promoting immune tolerance, regula
Autor:
Chin-San Loo, Bhargav Venkatraghavan, Mathias Leblanc, Josephine Ho, Yuqiong Liang, Diana C. Hargreaves, Jovylyn Gatchalian, Mingjun Xie, Ye Zheng
SummaryRegulatory T cells (Tregs) play a pivotal role in suppressing auto-reactive T cells and maintaining immune homeostasis. Treg development and function are dependent on the transcription factor Foxp3. Here we performed a genome-wide CRISPR/Cas9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06093d416f9e52bccfd8a103028bf079
https://doi.org/10.1101/2020.02.26.964981
https://doi.org/10.1101/2020.02.26.964981