Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Yuqing Huo"'
Autor:
Yongfeng Cai, Yaqi Zhou, Qiuhua Yang, Jiean Xu, Qingen Da, Qian Ma, Dingwei Zhao, Tammy Lu, Ha Won Kim, David Fulton, Xuejun Jiang, Neal L. Weintraub, Kunzhe Dong, Suowen Xu, Mei Hong, Zhiping Liu, Yuqing Huo
Publikováno v:
Pharmacological Research, Vol 203, Iss , Pp 107156- (2024)
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, and morbidity and mortality rates continue to rise. Atherosclerosis constitutes the principal etiology of CVDs. Endothelial injury, inflammation, and dysfunction are the initiat
Externí odkaz:
https://doaj.org/article/bb67af2f38d24a85a9e9c90882d9873a
Autor:
Syed A. H. Zaidi, Zhimin Xu, Tahira Lemtalsi, Porsche Sandow, Sruthi Athota, Fang Liu, Stephen Haigh, Yuqing Huo, S. Priya Narayanan, David J. R. Fulton, Modesto A. Rojas, Abdelrahman Y. Fouda, Robert W. Caldwell, Ruth B. Caldwell
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-13 (2023)
Abstract We previously found that global deletion of the mitochondrial enzyme arginase 2 (A2) limits optic nerve crush (ONC)-induced neuronal death. Herein, we examined the cell-specific role of A2 in this pathology by studies using wild type (WT), n
Externí odkaz:
https://doaj.org/article/1a43c41d16474a4bb0b5407c1612d0be
Autor:
Peng Wang, Rifeng Gao, Tingting Wu, Jinyan Zhang, Xiaolei Sun, Fan Fan, Cong Wang, Sanli Qian, Bingyu Li, Yunzeng Zou, Yuqing Huo, John Fassett, Yingjie Chen, Junbo Ge, Aijun Sun
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102884- (2023)
Adenosine kinase (ADK) plays the major role in cardiac adenosine metabolism, so that inhibition of ADK increases myocardial adenosine levels. While the cardioprotective actions of extracellular adenosine against ischemia/reperfusion (I/R) are well-es
Externí odkaz:
https://doaj.org/article/934b8c99c2984fd6973e193d027afd62
Autor:
Nathalie Paladines, Shantiece Dawson, Weston Ryan, Rogelio Serrano-Lopez, Regina Messer, Yuqing Huo, Christopher W. Cutler, Erivan S. Ramos-Junior, Ana Carolina Morandini
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionFibroblasts are the dominant stromal cells in the gingival lamina propria with a well-established relevance in regulation of inflammation, and in innate immunity. This is exemplified by their hypersecretion of CXCL8, enhancing leukocyte i
Externí odkaz:
https://doaj.org/article/64e3b579a21b43a4984b51d62dc991ce
Autor:
Mingjie Fan, Yangmeng Wang, Lihua Jin, Zhipeng Fang, Jiangling Peng, Jui Tu, Yanjun Liu, Eryun Zhang, Senlin Xu, Xiaoqian Liu, Yuqing Huo, Zhaoli Sun, Xiaojuan Chao, Wen-Xing Ding, Qingfeng Yan, Wendong Huang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 809-826 (2022)
Background & Aims: Alcohol-associated liver disease (AALD) is one of the most common causes of liver injury and failure. Limited knowledge of the mechanisms underlying AALD impedes the development of efficacious therapies. Bile acid (BA) signaling wa
Externí odkaz:
https://doaj.org/article/65cf997ee44144089c920bc96045e39f
Autor:
Di Xiang, Lei Jiang, Qiong Yuan, Yang Yu, Ruiming Liu, Meiting Chen, Zheng Kuai, Wendy Zhang, Fan Yang, Tingting Wu, Zhiyu He, Zuhui Ke, Wanzi Hong, Pengcheng He, Ning Tan, Yeying Sun, Zhen Shi, Xuebiao Wei, Jianfang Luo, Xiaoqiu Tan, Yuqing Huo, Gangjian Qin, Chunxiang Zhang
Publikováno v:
Research, Vol 6 (2023)
Monocyte-to-M0/M1 macrophage differentiation with unclear molecular mechanisms is a pivotal cellular event in many cardiovascular diseases including atherosclerosis. Long non-coding RNAs (lncRNAs) are a group of protein expression regulators; however
Externí odkaz:
https://doaj.org/article/bb40069e4dfa46238458def75133de2a
Autor:
Zhiping Liu, Huidong Shi, Jiean Xu, Qiuhua Yang, Qian Ma, Xiaoxiao Mao, Zhimin Xu, Yaqi Zhou, Qingen Da, Yongfeng Cai, David J.R. Fulton, Zheng Dong, Akrit Sodhi, Ruth B. Caldwell, Yuqing Huo
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
Pathological angiogenesis is a major cause of irreversible blindness in individuals of all age groups with proliferative retinopathy (PR). Mononuclear phagocytes (MPs) within neovascular areas contribute to aberrant retinal angiogenesis. Due to their
Externí odkaz:
https://doaj.org/article/d8faa0a88ffb4375acf7be6ca38fbe1b
Autor:
Jiean Xu, Lina Wang, Qiuhua Yang, Qian Ma, Yaqi Zhou, Yongfeng Cai, Xiaoxiao Mao, Qingen Da, Tammy Lu, Yunchao Su, Zsolt Bagi, Rudolf Lucas, Zhiping Liu, Mei Hong, Kunfu Ouyang, Yuqing Huo
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Sepsis, a pathology resulting from excessive inflammatory response that leads to multiple organ failure, is a major cause of mortality in intensive care units. Macrophages play an important role in the pathophysiology of sepsis. Accumulating evidence
Externí odkaz:
https://doaj.org/article/9347e206786c4b018ec1c48bc2cc7e1d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/e41cfa2874aa4fe7bbdb70442cb3033c
Autor:
Qiuhua Yang, Qian Ma, Jiean Xu, Zhiping Liu, Jianqiu Zou, Jian Shen, Yaqi Zhou, Qingen Da, Xiaoxiao Mao, Sarah Lu, David J. Fulton, Neal L. Weintraub, Zsolt Bagi, Mei Hong, Yuqing Huo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Myeloid cells, including monocytes/macrophages, primarily rely on glucose and lipid metabolism to provide the energy and metabolites needed for their functions and survival. AMP-activated protein kinase (AMPK, its gene is PRKA for human, Prka for rod
Externí odkaz:
https://doaj.org/article/4c62fe6b563b449385c46a47f4e5967a