Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Yuqing E, Chen"'
Autor:
Jinxue Ruan, Hiroyuki Hirai, Dongshan Yang, Linyuan Ma, Xia Hou, Hong Jiang, Hongguang Wei, Carthic Rajagopalan, Hongmei Mou, Guoshun Wang, Jifeng Zhang, Kui Li, Yuqing E. Chen, Fei Sun, Jie Xu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 73-81 (2019)
Cystic fibrosis (CF) is a lethal autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Nuclease-mediated precise gene editing (PGE) represents a promising therapy for CF, for which an
Externí odkaz:
https://doaj.org/article/a456badb163c4c67808cc465e0c667bc
Autor:
Linyuan Ma, Dongshan Yang, Hiroyuki Hirai, Hongmei Mou, Hong Jiang, Kui Li, Fei Sun, Yuqing E. Chen, Jifeng Zhang, Jinxue Ruan, Carthic Rajagopalan, Guoshun Wang, Jie Xu, Xia Hou, Hongguang Wei
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 16, Iss, Pp 73-81 (2019)
Molecular Therapy: Nucleic Acids, Vol 16, Iss, Pp 73-81 (2019)
Cystic fibrosis (CF) is a lethal autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Nuclease-mediated precise gene editing (PGE) represents a promising therapy for CF, for which an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a0b8faa7cc3f02e60a8ff5eff1aa27
https://doi.org/10.1016/j.omtn.2019.02.006
https://doi.org/10.1016/j.omtn.2019.02.006
Autor:
Dale Adam Lauver, James P. Teuber, Matthew P. Bernard, Dawn S. Kuszynski, Haoming Zhang, Barbara Christian, Yuqing E. Chen, Bruce E. Markham
Publikováno v:
Pharmacology Research & Perspectives. 7
The novel clopidogrel conjugate, DT-678, is an effective inhibitor of platelets and thrombosis in preclinical studies. However, a comparison of the bleeding risk with DT-678 and currently approved P2Y12 antagonists has yet to be determined. The objec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7484425491366dcaa6bfdf50803b482
https://doi.org/10.1002/prp2.509
https://doi.org/10.1002/prp2.509
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34:2217-2223
Obesity is a worldwide epidemic and is associated with multiple comorbidities. The mechanisms underlying the relationship between obesity and adverse health outcomes remain poorly understood. This may be because of several factors including the crude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df3f6257fc96e385013f8e1cad651a5
https://doi.org/10.1161/atvbaha.114.303036
https://doi.org/10.1161/atvbaha.114.303036
Autor:
Yuqing E. Chen, Ivana Massud, Rui Chai, Winston E. Thompson, Xiaojun Zhu, Lin Chang, Methode Bacanamwo, Minerva Garcia-Barrio, Yiming Lin, Jifeng Zhang
Publikováno v:
Cardiovascular Research. 76:141-148
Objective Id2 (inhibitor of DNA-binding 2), a member of the helix–loop–helix family of transcription regulators, plays important roles in cell proliferation and differentiation. Recent reports have documented that Id2 is up-regulated during vascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48706b1cdce78979b569818aafa55e12
https://doi.org/10.1016/j.cardiores.2007.06.015
https://doi.org/10.1016/j.cardiores.2007.06.015
Autor:
James S. Pankow, Yuqing E. Chen, Steven C. Hunt, Qingwei Wang, Qing Song, Michael A. Province, John H. Eckfeldt, Qin Xu
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 291:H2752-H2757
Recent epidemiological studies have indicated that baseline C-reactive protein (CRP) levels may have value in prediction of cardiovascular risk. Using six tag single-nucleotide polymorphisms (SNPs) selected from our complete list of SNPs on the CRP g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea25071c53ca35a8c8a3ff503261747
https://doi.org/10.1152/ajpheart.01164.2005
https://doi.org/10.1152/ajpheart.01164.2005
Publikováno v:
Vascular Pharmacology. 45:65-71
Given the heterogeneous nature of metabolic dysfunctions associated with insulin resistance and type 2 diabetes (T2D), a single pharmaceutical cannot be expected to provide complication-free therapy in all patients. Thiazolidinediones (TZD) increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74c96b5365ac14ea67a14c087b3b48c
https://doi.org/10.1016/j.vph.2005.11.011
https://doi.org/10.1016/j.vph.2005.11.011
Autor:
Yuqing E. Chen, Francisco J. Schopfer, Scott Sweeney, Carlos Batthyány, Yiming Lin, Paul R. S. Baker, Alison L. Groeger, Karen E. Iles, Laura M. S. Baker, Marshall H. Long, Steven R. Woodcock, Bruce P. Branchaud, Bruce A. Freeman
Publikováno v:
Journal of Biological Chemistry. 280:42464-42475
Mass spectrometric analysis of human plasma and urine revealed abundant nitrated derivatives of all principal unsaturated fatty acids. Nitrated palmitoleic, oleic, linoleic, linolenic, arachidonic and eicosapentaenoic acids were detected in concert w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06e8a9ad1a0cf4d3e8ed08be85d0d57f
https://doi.org/10.1074/jbc.m504212200
https://doi.org/10.1074/jbc.m504212200
Autor:
Masatoshi Morimoto, Shuji Kitajima, Masashi Shiomi, Tomonaga Ichikawa, Tomonari Koike, Kinta Hatakeyama, Yuqing E. Chen, Huijun Sun, Teruo Watanabe, Jianglin Fan, Bo Zhang, Yujiro Asada
Publikováno v:
The American Journal of Pathology. 167:1139-1148
C-reactive protein (CRP) is frequently deposited in the lesions of the arterial intima; however, the origin and pathological significance of CRP in these lesions are not completely understood. In this study, we measured CRP levels in the plasma of hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a2c128afec75240be351c166d1ed68b
https://doi.org/10.1016/s0002-9440(10)61202-3
https://doi.org/10.1016/s0002-9440(10)61202-3
Autor:
Chen Xiong, Mukaila A. Akinbami, Yongshan Mou, Yuqing E. Chen, Mingui Fu, Jifeng Zhang, Taixing Cui
Publikováno v:
Life Sciences. 77:3037-3048
Peroxisome proliferator-activated receptor gamma (PPAR gamma), a member of the nuclear receptor family, has been implicated in the regulation of vascular smooth muscle cell (VSMC) growth; however, the underlying mechanisms are still not fully underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de3e2fab35990d5808e64f08b303fc1
https://doi.org/10.1016/j.lfs.2005.02.032
https://doi.org/10.1016/j.lfs.2005.02.032