Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yuping Donsante"'
Publikováno v:
Neurobiology of Disease, Vol 168, Iss , Pp 105699- (2022)
Trihexyphenidyl (THP), a non-selective muscarinic receptor (mAChR) antagonist, is commonly used for the treatment of dystonia associated with TOR1A, otherwise known as DYT1 dystonia. A better understanding of the mechanism of action of THP is a criti
Externí odkaz:
https://doaj.org/article/1a227e4b422741cc8745040ef9891087
Autor:
Anthony M. Downs, Xueliang Fan, Radhika F. Kadakia, Yuping Donsante, H.A. Jinnah, Ellen J. Hess
Publikováno v:
Neurobiology of Disease, Vol 155, Iss , Pp 105369- (2021)
TOR1A-associated dystonia, otherwise known as DYT1 dystonia, is an inherited dystonia caused by a three base-pair deletion in the TOR1A gene (TOR1AΔE). Although the mechanisms underlying the dystonic movements are largely unknown, abnormalities in s
Externí odkaz:
https://doaj.org/article/1f0aea9f427b41ab97e4422a37d0b53d
Autor:
Kaitlyn M. Roman, Maria A. Briscione, Yuping Donsante, Jordan Ingram, Xueliang Fan, Douglas Bernhard, Simone A. Campbell, Anthony M. Downs, David Gutman, Tejas A. Sardar, Sofia Q. Bonno, Diane J. Sutcliffe, H.A. Jinnah, Ellen J. Hess
Publikováno v:
Neuroscience. 517:37-49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03b78a90a47ed156dc384f9383788163
https://doi.org/10.1016/j.neuroscience.2023.02.020
https://doi.org/10.1016/j.neuroscience.2023.02.020
Autor:
Jerri M. Rook, Aaron M. Bender, Colleen M. Niswender, Yuping Donsante, P. Jeffrey Conn, Hyekyung P. Cho, Li Peng, Julie L. Engers, Jonathan W. Dickerson, Thomas M. Bridges, Craig W. Lindsley, Ellen J. Hess, Sichen Chang, Aidong Qi, Weimin Peng, Mark S. Moehle, Jordan C. O’Neill, Daniel J. Foster, Alice L. Rodriguez, Zoey Bryant, Katherine J. Watson, Kaylee J. Stillwell
Publikováno v:
ACS Pharmacology & Translational Science. 4:1306-1321
Nonselective antagonists of muscarinic acetylcholine receptors (mAChRs) that broadly inhibit all five mAChR subtypes provide an efficacious treatment for some movement disorders, including Parkinson's disease and dystonia. Despite their efficacy in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5425dfe0a6fb74da410878130ec6660
https://doi.org/10.1021/acsptsci.0c00162
https://doi.org/10.1021/acsptsci.0c00162
Publikováno v:
Neurobiology of disease. 168
Trihexyphenidyl (THP), a non-selective muscarinic receptor (mAChR) antagonist, is commonly used for the treatment of dystonia associated with TOR1A, otherwise known as DYT1 dystonia. A better understanding of the mechanism of action of THP is a criti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14cf44d1827c121ef6830accfdd46bf
https://pubmed.ncbi.nlm.nih.gov/35314320
https://pubmed.ncbi.nlm.nih.gov/35314320
Autor:
Ellen J. Hess, Anthony M. Downs, Yuping Donsante, Xueliang Fan, Radhika F. Kadakia, H.A. Jinnah
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 155, Iss, Pp 105369-(2021)
Neurobiology of Disease, Vol 155, Iss, Pp 105369-(2021)
TOR1A-associated dystonia, otherwise known as DYT1 dystonia, is an inherited dystonia caused by a three base-pair deletion in the TOR1A gene (TOR1AΔE). Although the mechanisms underlying the dystonic movements are largely unknown, abnormalities in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564b44413b28a3c0f3424888d3b2433e
https://europepmc.org/articles/PMC8327367/
https://europepmc.org/articles/PMC8327367/
Autor:
Ellen J. Hess, Ashok Reddy Dinasarapu, H.A. Jinnah, Pritha Bagchi, Jessica Hoehner, Anthony M. Downs, Yuping Donsante, Kaitlyn M. Roman, Xueliang Fan, Maria A. Briscione
Publikováno v:
Mol Genet Metab
Dystonia is characterized by involuntary muscle contractions that cause debilitating twisting movements and postures. Although dysfunction of the basal ganglia, a brain region that mediates movement, is implicated in many forms of dystonia, the under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe2b430e77ddc315a56f4c504395935
https://pubmed.ncbi.nlm.nih.gov/34092491
https://pubmed.ncbi.nlm.nih.gov/34092491
Autor:
Xueliang Fan, Yuping Donsante, Maria A. Briscione, Pritha Bagchi, H.A. Jinnah, Ashok Reddy Dinasarapu, Ellen J. Hess, Jessica Hoehner, Anthony M. Downs
Dystonia is characterized by involuntary muscle contractions that cause debilitating twisting movements and postures. Although basal ganglia dysfunction is implicated in many forms of dystonia, the underlying mechanisms are unclear. Therefore, to rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01084823493dbd486a0c0843bef498d3
https://doi.org/10.1101/2021.01.12.426367
https://doi.org/10.1101/2021.01.12.426367
Autor:
Ellen J. Hess, Xueliang Fan, Yuping Donsante, Radhika F. Kadakia, Anthony M. Downs, H.A. Jinnah
DYT1-TOR1A dystonia is an inherited dystonia caused by a three base-pair deletion in the TOR1A gene (TOR1AΔE). Although the mechanisms underlying the dystonic movements are largely unknown, abnormalities in striatal dopamine and acetylcholine neurot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a7dbe3bce2b17550c9856832bc4b88d
https://doi.org/10.1101/2020.12.22.424006
https://doi.org/10.1101/2020.12.22.424006
Trihexyphenidyl (THP), a non-selective muscarinic receptor (mAChR) antagonist, is commonly used for the treatment of dystonia associated with TOR1A, otherwise known as DYT1 dystonia. A better understanding of the mechanism of action of THP is a criti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51f54f09f62640987600d31a8a6c4961
https://doi.org/10.1101/2020.12.17.423273
https://doi.org/10.1101/2020.12.17.423273