Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Yuping Cai"'
Autor:
Jiali Lv, Chang Pan, Yuping Cai, Xinyue Han, Cheng Wang, Jingjing Ma, Jiaojiao Pang, Feng Xu, Shuo Wu, Tianzhang Kou, Fandong Ren, Zheng-Jiang Zhu, Tao Zhang, Jiali Wang, Yuguo Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Risk prediction for subsequent cardiovascular events remains an unmet clinical issue in patients with coronary artery disease. We aimed to investigate prognostic metabolic biomarkers by considering both shared and distinct metabolic disturba
Externí odkaz:
https://doaj.org/article/4e6f9621c4a047baaf7ca0d10845b58a
Autor:
Bangmin Yin, Yuping Cai, Teng Teng, Xiaolin Wang, Xueer Liu, Xuemei Li, Jie Wang, Hongyan Wu, Yuqian He, Fandong Ren, Tianzhang Kou, Zheng-Jiang Zhu, Xinyu Zhou
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCZ) are classified as major mental disorders and together account for the second-highest global disease burden, and half of these patients experience symptom onset i
Externí odkaz:
https://doaj.org/article/71d867214af147af8833d9504e689c5b
Autor:
Yawen Sun, Wenjuan Liu, Mu Su, Tao Zhang, Xia Li, Wenbin Liu, Yuping Cai, Deli Zhao, Ming Yang, Zhengjiang Zhu, Jialin Wang, Jinming Yu
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Esophageal squamous cell carcinoma (ESCC) remains an important health concern in developing countries. Patients with advanced ESCC have a poor prognosis and survival rate, and achieving early diagnosis remains a challenge. Metabolic biomarke
Externí odkaz:
https://doaj.org/article/ade79b99b50a4e4ca18551a04bcd3188
Autor:
Hongmiao Wang, Huixun Jia, Yang Gao, Haosong Zhang, Jin Fan, Lijie Zhang, Fandong Ren, Yandong Yin, Yuping Cai, Ji Zhu, Zheng-Jiang Zhu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Neoadjuvant chemoradiotherapy is the standard treatment for patients with locally advanced rectal cancer, however, response can be limited by development of toxicities. Here, the authors conducted metabolomics on patients with locally advanced rectal
Externí odkaz:
https://doaj.org/article/51df00b5f5fa48b2ba32fe451ceee5e6
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Unknown metabolite annotation is a grand challenge in untargeted metabolomics. Here, the authors develop knowledge-guided multi-layer networking (KGMN) to enable global metabolite annotation from knowns to unknowns in untargeted metabolomics.
Externí odkaz:
https://doaj.org/article/d0fce2db786649db8813dc503b78bb03
Autor:
Hong Yan, Ronan Talty, Abhishek Jain, Yuping Cai, Jie Zheng, Xinyi Shen, Engjel Muca, Philip B. Paty, Marcus W. Bosenberg, Sajid A. Khan, Caroline H. Johnson
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102699- (2023)
Aberrant tumor metabolism is a hallmark of cancer in which metabolic rewiring can support tumor growth under nutrient deficient conditions. KRAS mutations occur in 35–45% of all colorectal cancer (CRC) cases and are difficult to treat. The relation
Externí odkaz:
https://doaj.org/article/5832ba66127c4a83b04dcd182cba5e22
Autor:
Yuping Cai, Xinyi Shen, Lingeng Lu, Hong Yan, Huang Huang, Patricia Gaule, Engjel Muca, Casey M. Theriot, Zahra Rattray, Nicholas J. W. Rattray, Jun Lu, Nita Ahuja, Yawei Zhang, Philip B. Paty, Sajid A. Khan, Caroline H. Johnson
Publikováno v:
Biology of Sex Differences, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Background Bile acids are known to be genotoxic and contribute to colorectal cancer (CRC). However, the link between CRC tumor bile acids to tumor location, patient sex, microbiome, immune-regulatory cells, and prognosis is not clear. Method
Externí odkaz:
https://doaj.org/article/0b5bcdaee79245478fd9882fb924ee7a
Autor:
Ruohong Wang, Yandong Yin, Jingshu Li, Hongmiao Wang, Wanting Lv, Yang Gao, Tangci Wang, Yedan Zhong, Zhiwei Zhou, Yuping Cai, Xiaoyang Su, Nan Liu, Zheng-Jiang Zhu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Stable-isotope tracing allows quantifying metabolic activity by measuring isotopically labeled metabolites, but its metabolome coverage has been limited. Here, the authors develop a global isotope tracing approach with metabolome-wide coverage and us
Externí odkaz:
https://doaj.org/article/08ee972f18e6467da914cc324ce00e83
Autor:
Tongzhou Li, Yandong Yin, Zhiwei Zhou, Jiaqian Qiu, Wenbin Liu, Xueting Zhang, Kaiwen He, Yuping Cai, Zheng-Jiang Zhu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Sterol lipids are crucial for maintaining proper brain function. Here, the authors combine ion mobility-mass spectrometry and machine learning to assemble a sterol lipid library and characterize differences in sterol lipids across ten brain regions a
Externí odkaz:
https://doaj.org/article/93e2745d67af43f4871d194c83d08ba0
Autor:
Xiaochen Yang, Wing Lam, Zaoli Jiang, Fulan Guan, Xue Han, Rong Hu, Wei Cai, William Cheng, Shwu-Huey Liu, Peikwen Cheng, Yuping Cai, Nicholas J. W. Rattray, Caroline H. Johnson, Lieping Chen, Yung-Chi Cheng
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract YIV-906 (PHY906) is a standardized botanical cancer drug candidate developed with a systems biology approach—inspired by a traditional Chinese herbal formulation, historically used to treat gastrointestinal symptoms including diarrhea, nau
Externí odkaz:
https://doaj.org/article/ae2979734ecc4108a42ccbc05970d901