Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yunyun Yeh"'
Autor:
Wen-Tien Chen, Yunyun Yeh, Lari Häkkinen, Leslie A. Goldstein, Hannu Larjava, Giulio Ghersi, Huan Dong
Publikováno v:
Journal of Biological Chemistry. 277:29231-29241
The invasion of migratory cells through connective tissues involves metallo- and serine types of cell surface proteases. We show that formation of a novel protease complex, consisting of the membrane-bound prolyl peptidases seprase and dipeptidyl pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80541c6413c2e8bee474ba50082373a
https://doi.org/10.1074/jbc.m202770200
https://doi.org/10.1074/jbc.m202770200
Autor:
Steven K. Akiyama, Linda Howard, Giulio Ghersi, Qing-Xiang Amy Sang, Hirokazu Nakahara, Wen-Tien Chen, Mayra L. Piñeiro-Sánchez, Yunyun Yeh, Susette C. Mueller
Publikováno v:
Journal of Biological Chemistry. 274:24947-24952
Invadopodia are membrane extensions of aggressive tumor cells that function in the activation of membrane-bound proteases occurring during tumor cell invasion. We explore a novel and provocative activity of integrins in docking proteases to sites of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90822f0a89da5ff71c82ea3a4e5e670
https://doi.org/10.1074/jbc.274.35.24947
https://doi.org/10.1074/jbc.274.35.24947
Autor:
Monica Salamone, Mayra L. Piñeiro-Sánchez, Denise Flessate, Giulio Ghersi, Leslie A. Goldstein, Wen-Tien Chen, Yunyun Yeh
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1361:11-19
Seprase is a homodimeric 170 kDa integral membrane gelatinase whose expression correlates with the invasiveness of the human melanoma cell line LOX. Here, we report the molecular cloning of a cDNA that encodes the 97 kDa subunit of seprase. Its deduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21060683988f193ed9eb0167eec09c5e
https://doi.org/10.1016/s0925-4439(97)00032-x
https://doi.org/10.1016/s0925-4439(97)00032-x
Autor:
Yoshihiko Yamada, Steven K. Akiyama, Wen-Tien Chen, Motoyoshi Nomizu, Hirokazu Nakahara, Yunyun Yeh
Publikováno v:
Journal of Biological Chemistry. 271:27221-27224
Invasion of LOX human melanoma cells involves extracellular matrix (ECM) degradation and formation of cell surface invadopodia. Here we show that the ligation of alpha6beta1 by two peptides derived from the COOH-terminal globular domain of laminin-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13d7d90f0642b9d4979258133e91ced5
https://doi.org/10.1074/jbc.271.44.27221
https://doi.org/10.1074/jbc.271.44.27221
Publikováno v:
Journal of Tissue Culture Methods. 16:177-181
A correlative morphological and biochemical method is described that facilitates assaying the invasive phenotype of tumor cells in vitro. The method involves a labeled matrix substrata to measure the activity of cell surface proteases, and uses the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfd82eeb9bb555cd2f643dc6fb8149a5
https://doi.org/10.1007/bf01540646
https://doi.org/10.1007/bf01540646
Publikováno v:
Journal of Cellular Physiology. 158:299-308
Chicken embryo fibroblasts (CEF) transformed by Rous sarcoma virus invade the extracellular matrix (ECM) using plasma membrane protrusions, termed invadopodia, that contact and dissolve the matrix. Normal cells neither form invadopodia nor degrade th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b51f67a0fcb72b73930c2a6135a067c4
https://doi.org/10.1002/jcp.1041580212
https://doi.org/10.1002/jcp.1041580212
Publikováno v:
The Journal of Cell Biology
Tyrosine phosphorylation of membrane-associated proteins is involved at two distinct sites of contact between cells and the extracellular matrix: adhesion plaques (cell adhesion and de-adhesion) and invadopodia (invasion into the extracellular matrix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e63ed39f48aa3d235fa85aacf470c2d
http://europepmc.org/articles/PMC2289729
http://europepmc.org/articles/PMC2289729
Dipeptidyl peptidase IV (DPP4/CD26) and seprase/fibroblast activation protein α are homologous type II transmembrane, homodimeric glycoproteins that exhibit unique prolyl peptidase activities. Human DPP4 is ubiquitously expressed in epithelial and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436c1c29058ad330201996efa12f1731
http://hdl.handle.net/10447/18234
http://hdl.handle.net/10447/18234
Autor:
Dong H, Yunyun Yeh, Giulio Ghersi, Hannu Larjava, Wen-Tien Chen, Lari Häkkinen, Leslie A. Goldstein
Publikováno v:
Dipeptidyl Aminopeptidases in Health and Disease ISBN: 0306477173
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4f8cc99943087564906b2447abb9c39
https://doi.org/10.1007/0-306-47920-6_11
https://doi.org/10.1007/0-306-47920-6_11
Autor:
Janice Rone, Hong Ji, Ewa Karwatowska-Prokopczuk, Derrick S. Grant, Hynda K. Kleinman, Zofia Zukowska-Grojec, Wesley Rose, Eric Grouzmann, Wen-Tien Chen, Yunyun Yeh, Sharareh Movafagh
Publikováno v:
Circulation research. 83(2)
Abstract —Sympathetic nerves have long been suspected of trophic activity, but the nature of their angiogenic factor has not been determined. Neuropeptide Y (NPY), a sympathetic cotransmitter, is the most abundant peptide in the heart and the brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb12030a416ac0773502cdd81c5a6d4
https://pubmed.ncbi.nlm.nih.gov/9686758
https://pubmed.ncbi.nlm.nih.gov/9686758