Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Yunxia O'Malley"'
Autor:
Yunxia O'Malley, Mitchell C. Coleman, Xingshen Sun, Junying Lei, Jianrong Yao, Casey F. Pulliam, Paige Kluz, Michael L. McCormick, Yaling Yi, Yumi Imai, John F. Engelhardt, Andrew W. Norris, Douglas R. Spitz, Aliye Uc
Publikováno v:
Advances in Redox Research, Vol 5, Iss , Pp 100040- (2022)
Cystic fibrosis-related diabetes (CFRD) is one the most common comorbidities in cystic fibrosis (CF). Pancreatic oxidative stress has been postulated in the pathogenesis of CFRD, but no studies have been done to show an association. The main obstacle
Externí odkaz:
https://doaj.org/article/522cd40a4710415fae812e3ff30a32cd
Autor:
Orlando DeLeon, Hagit Hodis, Yunxia O'Malley, Jacklyn Johnson, Hamid Salimi, Yinjie Zhai, Elizabeth Winter, Claire Remec, Noah Eichelberger, Brandon Van Cleave, Ramya Puliadi, Robert D Harrington, Jack T Stapleton, Hillel Haim
Publikováno v:
PLoS Biology, Vol 15, Iss 4, p e2001549 (2017)
The envelope glycoproteins (Envs) of HIV-1 continuously evolve in the host by random mutations and recombination events. The resulting diversity of Env variants circulating in the population and their continuing diversification process limit the effi
Externí odkaz:
https://doaj.org/article/b600c1642ef54780a6ca2f16c13cab36
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39430 (2012)
It has been suggested that cells that are independent of insulin for glucose uptake, when exposed to high glucose or other nutrient concentrations, manifest enhanced mitochondrial substrate oxidation with consequent enhanced potential and generation
Externí odkaz:
https://doaj.org/article/8d4636f19da9407a85179165a467251a
Autor:
Brian D Fink, Yunxia O'Malley, Brian L Dake, Nicolette C Ross, Thomas E Prisinzano, William I Sivitz
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4250 (2009)
Previously, we reported that the "antioxidant" compound "mitoQ" (mitochondrial-targeted ubiquinol/ubiquinone) actually increased superoxide production by bovine aortic endothelial (BAE) cell mitochondria incubated with complex I but not complex II su
Externí odkaz:
https://doaj.org/article/770b3a928ff743819462d9ac36e9677c
Autor:
Patrick M. Schlievert, Jacklyn Johnson, Jon C. D. Houtman, Michael S. Zhang, Hillel Haim, Manuel G Flores, Hamid Salimi, Yunxia O'Malley
Publikováno v:
J Biol Chem
The envelope glycoproteins (Envs) of HIV-1 are embedded in the cholesterol-rich lipid membrane of the virus. Chemical depletion of cholesterol from HIV-1 particles inactivates their infectivity. We observed that diverse HIV-1 strains exhibit a range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba6539b449a4cc985bcab1d6ee023f3
https://doi.org/10.1074/jbc.ra119.009481
https://doi.org/10.1074/jbc.ra119.009481
Autor:
Andrew W. Norris, Yunxia O'Malley, Idil Apak-Evans, Aliye Uc, Pavana G. Rotti, John F. Engelhardt
Publikováno v:
Diabetes. 68
Cystic fibrosis (CF) is a multi-organ disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CFTR protein is most highly expressed in pancreatic ductal epithelium, where loss of its function leads to ducta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f21766f471ab70b3807da40e769bf9b
https://doi.org/10.2337/db19-1842-p
https://doi.org/10.2337/db19-1842-p
Autor:
Joseph Zabner, Pavana G. Rotti, Xiaopeng Li, Zheng Zhu, Oriana G. Vanegas Calderón, Ian M. Thornell, Jianrong Yao, Yunxia O'Malley, Christopher A. Febres-Aldana, John F. Engelhardt, Aliye Uc, Katelin Durham, Andrew W. Norris
Pancreatic ductular epithelial cells comprise the majority of duct cells in pancreas, control cystic fibrosis transmembrane conductance regulator (CFTR)-dependent bicarbonate ([Formula: see text]) secretion, but are difficult to grow as a polarized m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ba29cca4c53da52660cac2e0eabca9
https://europepmc.org/articles/PMC6086968/
https://europepmc.org/articles/PMC6086968/
Autor:
Hillel Haim, Noah Eichelberger, Hamid Salimi, Yunxia O'Malley, Jacklyn Johnson, Joseph Sodroski, Joel R. Courter, Nicole Espy, Orlando DeLeon, Yinjie Zhai, Navid Madani, Amos B. Smith
The envelope glycoproteins (Envs) on the surfaces of HIV-1 particles are targeted by host antibodies. Primary HIV-1 isolates demonstrate different global sensitivities to antibody neutralization; tier-1 isolates are sensitive, whereas tier-2 isolates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032517dac090f6db405524f32260d5f3
https://europepmc.org/articles/PMC5512248/
https://europepmc.org/articles/PMC5512248/
Autor:
Ronald J. Weigel, Alicia K. Olivier, Frederick E. Domann, Mikhail V. Kulak, Philip M. Spanheimer, Lola S. White-Baer, Maria V. Bogachek, Weizhou Zhang, George W. Woodfield, Jung M. Park, Yunxia O'Malley, Anthony R. Cyr, Sonia L. Sugg
Publikováno v:
Oncogene
Molecular subtypes of breast cancer are characterized by distinct patterns of gene expression that are predictive of outcome and response to therapy. The luminal breast cancer subtypes are defined by the expression of estrogen receptor-alpha (ERα)-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff802e74cd812013cdfa70db174ec429
http://europepmc.org/articles/PMC4112181
http://europepmc.org/articles/PMC4112181
Autor:
Rory A. Fisher, Ryan W. Askeland, Adele Stewart, Biswanath Maity, Sonia L. Sugg, Yunxia O'Malley
Publikováno v:
Carcinogenesis. 34:1747-1755
Breast cancer is a large global health burden and the most frequently diagnosed malignancy in women worldwide. Here, we utilize RGS6(-/-) mice to interrogate the role of regulator of G protein signaling 6 (RGS6), localized to the ductal epithelium in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d64acb48b64142730e4bb9b2da6dc4
https://doi.org/10.1093/carcin/bgt128
https://doi.org/10.1093/carcin/bgt128