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Autor:
Mohamed Bouyakhrichan, Esther H.M Belshof, Jos H. Beijnen, Rianne J. van Maanen, Willy J. M. Underberg, Yunus Kellekule, Auke Bult, J.Léon E. Reubsaet, Ed Hop, Jan Teeuwsen
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 19:277-284
The tripeptides Arg-Trp-Phe, Arg-Trp-Phe-NH2, Phe-Trp-Arg and Phe-Trp-Arg-NH2 were subjected to a degradation study to get a more detailed insight into the degradation processes of the antitumor hexapeptide antagonist [Arg(6), D-Trp(7,9), MePhe(8)] s