Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Yunus A Luqmani"'
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0272449 (2022)
BackgroundBreast cancer chemotherapy with high dose alkylating agents is severely limited by their collateral toxicity to crucial normal tissues such as immune and gut cells. Taking advantage of the selective dependence of cancer cells on high glucos
Externí odkaz:
https://doaj.org/article/0e306d984ec949429aeda96b8f02111f
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252820 (2021)
Three scarce terpenes, psiadin, plectranthone and saudinolide, were obtained after chromatographic isolation and purification from the aerial parts of the respective plants. Their identities were established based on their spectral data. Their antica
Externí odkaz:
https://doaj.org/article/649562420b71478d9ae57745659dbafe
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193779 (2018)
The Na+/K+-ATPase (NKP) is an important ion transporter also involved in signal transduction. Its expression profile is altered in various tumours including that of the breast. We studied the effect of inhibiting NKP activity in non-tumorigenic breas
Externí odkaz:
https://doaj.org/article/305f04793dca411881fe1fc1f52e1fdf
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150861 (2016)
BACKGROUND:There is evidence to support a role for angiotensin (Ang) 1-7 in reducing the activity of inflammatory signaling molecules such as MAPK, PKC and SRC. Enhanced angiotensin converting enzyme 2 (ACE2) expression has been observed in patients
Externí odkaz:
https://doaj.org/article/8fb0547b80f745e4b68aaa0a1f8a44ee
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54361 (2013)
PURPOSE: To examine whether (99m)Tc(V)-DMSA could be used as a non-invasive measure of cancer cell proliferation. METHODS: Human breast cancer MCF-7, MDA-MB-231 and pII, and prostate cancer PC-3 cell lines were grown to 30, 50 and 100% confluency and
Externí odkaz:
https://doaj.org/article/3054ed6c0a77405ab97d60764b2230ae
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76327 (2013)
INTRODUCTION: Endocrine resistance in breast cancer is associated with enhanced metastatic potential and poor clinical outcome, presenting a significant therapeutic challenge. We have established several endocrine insensitive breast cancer lines by s
Externí odkaz:
https://doaj.org/article/36dd2dfb7f36432b8b10e8541ad0fbba
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57827 (2013)
Microglia activation results in release of proinflammatory molecules including cytokines, which contribute to neuronal damage in the central nervous system (CNS) if not controlled. Tetracycline antibiotics such as minocycline inhibit microglial activ
Externí odkaz:
https://doaj.org/article/358dd23f5d814252a4d8bcffab18bbef
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41847 (2012)
We have established several breast cancer cell lines that exhibit a permanent ER-depleted phenotype, induced by shRNA transfection of MCF-7 cells, which afford a useful model for studying acquired endocrine resistance. Previously we showed that MDA-2
Externí odkaz:
https://doaj.org/article/e0d1f49932ab40ccadcdc8862c9425d1
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20610 (2011)
We propose the hypothesis that loss of estrogen receptor function which leads to endocrine resistance in breast cancer, also results in trans-differentiation from an epithelial to a mesenchymal phenotype that is responsible for increased aggressivene
Externí odkaz:
https://doaj.org/article/bf2dc64b8e1b4b6da6ceb751107b2be1
Publikováno v:
Biochemistry and biophysics reports. 31
MicroRNAs (miRs) regulate gene expression through translation inhibition of target mRNAs. One of the most promising approaches for cancer therapy is through mimicking or antagonizing the action of miRs. In this report, we analyzed the miRnome profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007230380d8376fb20219ce5328a8f5c
https://pubmed.ncbi.nlm.nih.gov/35879960
https://pubmed.ncbi.nlm.nih.gov/35879960