Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Yunqing Cai"'
Autor:
Victoria L. Slaughter, John W. Rumsey, Rachel Boone, Duaa Malik, Yunqing Cai, Narasimhan Narasimhan Sriram, Christopher J. Long, Christopher W. McAleer, Stephen Lambert, Michael L. Shuler, J. J. Hickman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease and strongly correlates with the growing incidence of obesity and type II diabetes. We have developed a human-on-a-chip model composed of human hepatocytes and adipose
Externí odkaz:
https://doaj.org/article/3547c91f62364f5898fce5860fb718e0
Publikováno v:
Molecules, Vol 17, Iss 6, Pp 7206-7216 (2012)
Angiogenesis is one of the crucial steps in the transition of a tumor from a small, harmless cluster of mutated cells to a large, malignant growth, capable of spreading to other organs throughout the body. Vascular endothelial growth factor (VEGF) th
Externí odkaz:
https://doaj.org/article/40be2951e7fc4575b5a3a1606d1e0a51
Autor:
Yunqing Cai, Michael L. Shuler, Narasimhan Narasimhan Sriram, Christopher J. Long, Duaa Malik, Victoria L. Slaughter, Rachel Boone, Christopher W. McAleer, Stephen Lambert, John W. Rumsey, James J. Hickman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease and strongly correlates with the growing incidence of obesity and type II diabetes. We have developed a human-on-a-chip model composed of human hepatocytes and adipose tissue c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48e79795bf3b3db7d946cf3ceefe2e9
https://doaj.org/article/3547c91f62364f5898fce5860fb718e0
https://doaj.org/article/3547c91f62364f5898fce5860fb718e0
Publikováno v:
Biomaterials. 289
There is evidence for the involvement of human skeletal muscle (hSKM) in ALS neuromuscular junction (NMJ) dysfunction. However, the specific avenue by which the hSKM contributes to NMJ disruption is not well understood due to limited human-based stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a809d93e707355a8fdf0b3aaf4c72e9
https://pubmed.ncbi.nlm.nih.gov/36084484
https://pubmed.ncbi.nlm.nih.gov/36084484
Autor:
Christopher J. Long, Alexander S.T. Smith, Candace Martin, Yunqing Cai, Christopher W. McAleer, Sarah A. Najjar, James J. Hickman, Balaji Srinivasan, Herman H. Vandenburgh
Publikováno v:
Biotechnol Bioeng
In vitro systems that mimic organ functionality have become increasingly important tools in drug development studies. Systems that measure the functional properties of skeletal muscle are beneficial to compound screening studies and also for integrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3372ff95337a14f3dfa7f373def59984
https://doi.org/10.1002/bit.27231
https://doi.org/10.1002/bit.27231
Autor:
Max Jackson, Virginia M. Smith, Michael C Thomas, Christopher J. Long, Yunqing Cai, My Tran, Eric Lorusso, Siddharth Nimbalkar, Xiufang Guo, Ying Wang, Aakash Patel, Christopher W. McAleer, James J. Hickman
Publikováno v:
Adv Ther (Weinh)
Loss of the neuromuscular junction (NMJ) is an early and critical hallmark in all forms of ALS. The study design was to develop a functional NMJ disease model by integrating motoneurons (MNs) differentiated from multiple ALS-patients' induced pluripo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805733b25ed00f0de4a7adbec8eb70d4
https://pubmed.ncbi.nlm.nih.gov/33709015
https://pubmed.ncbi.nlm.nih.gov/33709015
Autor:
Andrea, Lavado, Xiufang, Guo, Alec St, Smith, Nesar, Akanda, Candace, Martin, Yunqing, Cai, Dan, Elbrecht, My, Tran, Jean-Paul, Bryant, Alisha, Colon, Christopher J, Long, Stephen, Lambert, Dave, Morgan, James J, Hickman
Publikováno v:
International journal of pharmacy and pharmaceutical research. 11(1)
There has been a tremendous amount of research into the causes of Amyotrophic Lateral Sclerosis (ALS), but yet very few treatment options beyond amelioration of symptoms. A holistic approach has shown anecdotal evidence of slowing disease progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::622d92f8b0778a266e0e69b4af3c9ff6
https://pubmed.ncbi.nlm.nih.gov/30637316
https://pubmed.ncbi.nlm.nih.gov/30637316
Autor:
Carlota Oleaga, Andrea Lavado, Anne Riu, Sandra Rothemund, Carlos A. Carmona‐Moran, Keisha Persaud, Andrew Yurko, Jennifer Lear, Narasimhan Sriram Narasimhan, Christopher J. Long, Frank Sommerhage, Lee Richard Bridges, Yunqing Cai, Candace Martin, Mark T. Schnepper, Arindom Goswami, Reine Note, Jessica Langer, Silvia Teissier, José Cotovio, James J. Hickman
Publikováno v:
Adv Funct Mater
The goal of human-on-a-chip systems is to capture multi-organ complexity and predict the human response to compounds within physiologically relevant platforms. The generation and characterization of such systems is currently a focal point of research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56649b7db9cc01f84898d059830af096
https://europepmc.org/articles/PMC9113405/
https://europepmc.org/articles/PMC9113405/
Autor:
Daisheng Zhang, Yunqing Cai
Publikováno v:
IOP Conference Series: Materials Science and Engineering. 811:012052
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f51f1bf6ba9eb27cc26c50cd8aedc89
https://doi.org/10.1088/1757-899x/811/1/012052
https://doi.org/10.1088/1757-899x/811/1/012052
Autor:
Xiufang Guo, Candace Martin, Max Jackson, Frank Sommerhage, Ying Wang, George Saad, Christopher J. Long, Navaneetha Santhanam, Yunqing Cai, Andrea Lavado, Christopher W. McAleer, Lee Kumanchik, James J. Hickman
Publikováno v:
Biomaterials. 166
There are currently no functional neuromuscular junction (hNMJ) systems composed of human cells that could be used for drug evaluations or toxicity testing in vitro. These systems are needed to evaluate NMJs for diseases such as amyotrophic lateral s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14180fb2dab7df72474045905818527d
https://pubmed.ncbi.nlm.nih.gov/29547745
https://pubmed.ncbi.nlm.nih.gov/29547745