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Autor:
Wakata Akihiro, Makita Tokutaro, Yagi Kimie, Hirabayashi Keiko, Kasahara Yoshinori, Yuno Kouichiro, Nakai Yasuharu, Miura Daishiro
Publikováno v:
Mutation research. 278(2-3)
The induction of micronuclei by methotrexate (MTX) was examined in two laboratories using mouse peripheral blood reticulocytes. MTX was a weak inducer in the micronucleus test using bone marrow cells and single treatments, and was one of the few chem