Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Yunn-Chyn Tung"'
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-18 (2020)
Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of middle-aged to old individuals. The pathophysiological process of AD is believed to begin many years before the emergence of clinical symptoms. The importan
Externí odkaz:
https://doaj.org/article/33b61968ce294e889924b5b3eb06bccb
Autor:
Syed Faraz Kazim, Julie Blanchard, Chun-Ling Dai, Yunn-Chyn Tung, Frank M. LaFerla, Inge-Grundke Iqbal, Khalid Iqbal
Publikováno v:
Neurobiology of Disease, Vol 71, Iss , Pp 110-130 (2014)
Besides the presence of amyloid beta (Aβ) plaques and neurofibrillary tangles, neurogenesis and synaptic plasticity are markedly impaired in Alzheimer's disease (AD) possibly contributing to cognitive impairment. In this context, neurotrophic factor
Externí odkaz:
https://doaj.org/article/755755e02a9e4366a0fe317954ae6776
Autor:
Nana Jin, Jianlan Gu, Ruozhen Wu, Dandan Chu, Yunn Chyn Tung, Jerzy Wegiel, Thomas Wisniewski, Cheng-Xin Gong, Khalid Iqbal, Fei Liu
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-20 (2022)
Abstract Propagation of tau pathology via the seeding of naive tau aggregation underlies the progression of Alzheimer’s disease (AD) and related tauopathies. Individuals with Down syndrome (DS) develop tau pathology at the fourth decade of life, bu
Externí odkaz:
https://doaj.org/article/d374f4940eeb403790e9f50b07df8939
Autor:
Fei Liu, Ruozhen Wu, Nana Jin, Dandan Chu, Jianlan Gu, Yunn Chyn Tung, Zhihao Hu, Cheng-Xin Gong, Khalid Iqbal
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
The regional distribution of neurofibrillary tangles of hyperphosphorylated tau aggregates is associated with the progression of Alzheimer’s disease (AD). Misfolded proteopathic tau recruits naïve tau and templates its misfolding and aggregation i
Externí odkaz:
https://doaj.org/article/e752612289d7476dafaf56c7e75bd1a0
Autor:
Fei Liu, Longfei Li, Jin Miao, Dandan Chu, Nana Jin, Yunn Chyn Tung, Chunling Dai, Wen Hu, Cheng‐Xin Gong, Khalid Iqbal
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1fbf7bbd10b8849b665fefd3219d716
https://doi.org/10.1002/alz.067128
https://doi.org/10.1002/alz.067128
Autor:
Longfei Li, Jin Miao, Dandan Chu, Nana Jin, Yunn Chyn Tung, Chun‐Ling Dai, Wen Hu, Cheng‐Xin Gong, Khalid Iqbal, Fei Liu
Publikováno v:
CNS neurosciencetherapeutics. 28(12)
Neurofibrillary tangle (NFT) of hyperphosphorylated tau is a hallmark of Alzheimer's disease (AD) and related tauopathies. Tau lesion starts in the trans-entorhinal cortex, from where it spreads to limbic regions, followed by neocortical areas. The r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144eac75b7358d7ae65429a18526da5c
https://pubmed.ncbi.nlm.nih.gov/36114722
https://pubmed.ncbi.nlm.nih.gov/36114722
Autor:
Fei Liu, Chu Dandan, Yan Zhou, Khalid Iqbal, Dingwei Zhou, Kevin Deng, Yunn Chyn Tung, Jianlan Gu, Cheng-Xin Gong, Ruirui Shi, Ruozhen Wu, Nana Jin, Jiawei Xu, Longfei Li
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Neurofibrillary tangles (NFTs) made of abnormally hyperphosphorylated tau are a hallmark of Alzheimer’s disease (AD) and related tauopathies. Regional distribution of NFTs is associated with the progression of the disease and has been proposed to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9533911fc447e135b44bad4eb84ec829
https://doaj.org/article/9e26ae6fedb94184b7615599f93b7355
https://doaj.org/article/9e26ae6fedb94184b7615599f93b7355
Autor:
Ruozhen Wu, Longfei Li, Ruirui Shi, Yan Zhou, Nana Jin, Jianlan Gu, Yunn Chyn Tung, Fei Liu, Dandan Chu
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Accumulation of intracellular neurofibrillary tangles (NFTs), which are constituted of abnormally phosphorylated tau, is one of the neuropathological hallmarks of Alzheimer’s disease (AD). The oligomeric aggregates of tau in AD brain (AD O-tau) are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc86ba43f8134e00efb13af63c1e78dd
http://europepmc.org/articles/PMC8155256
http://europepmc.org/articles/PMC8155256
Publikováno v:
Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-18 (2020)
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-18 (2020)
Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of middle-aged to old individuals. The pathophysiological process of AD is believed to begin many years before the emergence of clinical symptoms. The important influen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20bcb22467afb22b2fed344dd0a99ed
https://pubmed.ncbi.nlm.nih.gov/32854771
https://pubmed.ncbi.nlm.nih.gov/32854771
Publikováno v:
Journal of Alzheimer's Disease
Traumatic brain injury (TBI) is an established risk factor for the development of neurodegeneration and dementia late in life. Repetitive mild TBI (r-mTBI) is directly associated with chronic traumatic encephalopathy (CTE), a progressive neurodegener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b1ce703670fb8af9ae92ba031ad2fb
https://doi.org/10.3233/jad-180177
https://doi.org/10.3233/jad-180177