Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Yunkwon Nam"'
Autor:
Yunkwon Nam, Yun-Jeong Ji, Soo Jung Shin, Hyun Ha Park, Sung-Hum Yeon, Sang-Yoon Kim, Rak Ho Son, Gwi Yeong Jang, Hyung Don Kim, Minho Moon
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117090- (2024)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease accompanied by irreversible cognitive impairment. A deleterious feedback loop between oxidative stress and neuroinflammation in early AD exacerbates AD-related pathology. Platycodo
Externí odkaz:
https://doaj.org/article/f59e1a933db9495cb90e3b6bf740cec0
Autor:
Yunkwon Nam, Ritu Prajapati, Sujin Kim, Soo Jung Shin, Da Yeon Cheong, Yong Ho Park, Hyun Ha Park, Danyou Lim, Yoojeong Yoon, Gyudo Lee, Hyun Ah Jung, Insu Park, Dong-Hyun Kim, Jae Sue Choi, Minho Moon
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116226- (2024)
Alzheimer’s disease (AD) is characterized by the presence of two critical pathogenic factors: amyloid-β (Aβ) and tau. Aβ and tau become neurotoxic aggregates via self-assembly, and these aggregates contribute to the pathogenesis of AD. Therefore
Externí odkaz:
https://doaj.org/article/fed99a7f20a04370badd454bec09968e
Autor:
Sujin Kim, Da Gyeong Hyun, Yunkwon Nam, Soo Jung Shin, Dongjoon Im, Hyeon soo Kim, Seol Hwa Leem, Hyun Ha Park, Byeong-Hyeon Kim, Yong Ho Park, Eunbi Cho, William A. Goddard, III, Dong Hyun Kim, Hugh I. Kim, Minho Moon
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115770- (2023)
Alzheimer's disease (AD) is characterized by the aggregation of disordered proteins, such as amyloid beta (Aβ) and tau, leading to neurotoxicity and disease progression. Despite numerous efforts, effective inhibitors of Aβ and tau aggregates have n
Externí odkaz:
https://doaj.org/article/9ef65016f58d46a0b703c5002555f991
Autor:
Sujin Kim, Yunkwon Nam, Min-jeong Kim, Seung-hyun Kwon, Junhyeok Jeon, Soo Jung Shin, Soyoon Park, Sungjae Chang, Hyun Uk Kim, Yong Yook Lee, Hak Su Kim, Minho Moon
Publikováno v:
Journal of Ginseng Research, Vol 47, Iss 2, Pp 302-310 (2023)
Background: The most common type of dementia, Alzheimer's disease (AD), is marked by the formation of extracellular amyloid beta (Aβ) plaques. The impairments of axons and synapses appear in the process of Aβ plaques formation, and this damage coul
Externí odkaz:
https://doaj.org/article/4df96c8f209942d4988e9f92c8eb1055
Autor:
Hyeon soo Kim, Sujin Kim, Soo Jung Shin, Yong Ho Park, Yunkwon Nam, Chae won Kim, Kang won Lee, Sung-Min Kim, In Duk Jung, Hyun Duk Yang, Yeong-Min Park, Minho Moon
Publikováno v:
Translational Neurodegeneration, Vol 10, Iss 1, Pp 1-23 (2021)
Abstract Alzheimer’s disease (AD) is the most serious age-related neurodegenerative disease and causes destructive and irreversible cognitive decline. Failures in the development of therapeutics targeting amyloid-β (Aβ) and tau, principal protein
Externí odkaz:
https://doaj.org/article/c95d9bb4f3fd4f94b191926c24f9bc11
Autor:
Sujin Kim, Yunkwon Nam, Soo Jung Shin, Ritu Prajapati, Seong Min Shin, Min-Jeong Kim, Hyeon soo Kim, Seol Hwa Leem, Tae-Jin Kim, Yong Ho Park, Jwa-Jin Kim, Jae Sue Choi, Minho Moon
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113865- (2022)
A prominent characteristic of Alzheimer's disease (AD) is the deposition of both amyloid-β (Aβ) peptide and tau protein in the brain. Aβ and tau not only induce toxicity through self-aggregation but also induce more potent toxicity through the syn
Externí odkaz:
https://doaj.org/article/dbf55ce1c52f4eec8101286d8e54f14b
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Alzheimer’s disease (AD) is a neurodegenerative disease that is characterized by irreversible cognitive declines. Senile plaques formed by amyloid-β (Aβ) peptides and neurofibrillary tangles, consisting of hyperphosphorylated tau protein accumula
Externí odkaz:
https://doaj.org/article/5b306f2ffa87487e8f8427dfa33c6567
Autor:
Seung-Eun Lee, Saetbyeol Park, Gwi Yeong Jang, Jeonghoon Lee, Minho Moon, Yun-Jeong Ji, Ji Wook Jung, Yunkwon Nam, Soo Jung Shin, Yunji Lee, Jehun Choi, Dong Hwi Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5765 (2023)
Aster koraiensis Nakai (AK) leaf reportedly ameliorates health problems, such as diabetes. However, the effects of AK on cognitive dysfunction or memory impairment remain unclear. This study investigated whether AK leaf extract could attenuate cognit
Externí odkaz:
https://doaj.org/article/001878d7e84246b985d85e572ceb35cc
Publikováno v:
Cells, Vol 11, Iss 23, p 3901 (2022)
Amyloid-β (Aβ) deposition and Aβ-induced neurodegeneration appear in the retina and retinorecipient areas in the early stages of Alzheimer’s disease (AD). Although these Aβ-related changes in the retina cause damage to the visual functions, no
Externí odkaz:
https://doaj.org/article/8a47553f7683432c957a5547b81881c1
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Alzheimer’s disease (AD) is an irreversible neurodegenerative brain disorder with aggregation of amyloid-beta (Aβ) and tau as the pathological hallmarks. AD is the most common form of dementia and is characterized by a progressive decline of cogni
Externí odkaz:
https://doaj.org/article/2ec178aeb5a945e5952d77ae1ed81d8c