Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yunkun Qu"'
Autor:
Rui Lu, Yunkun Qu, Zhenggang Wang, Zhiyi He, Shimeng Xu, Peng Cheng, Zhengtao Lv, Hongbo You, Fengjing Guo, Anmin Chen, Jiaming Zhang, Shuang Liang
Publikováno v:
Journal of Orthopaedic Translation, Vol 47, Iss , Pp 207-222 (2024)
Objectives: TANK-binding kinase 1 (TBK1) is pivotal in autoimmune and inflammatory diseases, yet its role in osteoarthritis (OA) remains elusive. This study sought to elucidate the effect of the TBK1 inhibitor BX795 on OA and to delineate the underly
Externí odkaz:
https://doaj.org/article/fede2b11d8404b65a820a8cbf5153851
Autor:
Shanxi Wang, Yunkun Qu, Xuan Fang, Qing Ding, Hongqi Zhao, Xiaojun Yu, Tao Xu, Rui Lu, Shaoze Jing, Chaoxu Liu, Hua Wu, Yang Liu
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 7, Pp 1413-1423 (2023)
Abstract Ligamentum flavum hypertrophy (LFH) is the main physiological and pathological mechanism of lumbar spinal canal stenosis (LSCS). The specific mechanism for LFH has not been completely clarified. In this study, bioinformatic analysis, human l
Externí odkaz:
https://doaj.org/article/5e1c7e271e4a4e32b82dfdec60625ba9
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 171, Iss , Pp 116194- (2024)
Osteoarthritis (OA) is a prevalent degenerative disease that impairs limb function, and its pathogenesis is closely related to inflammation. Sakuranetin (SK) is a cherry flavonoid phytoalexin with potent anti-inflammatory, anti-oxidant, and ant-ifung
Externí odkaz:
https://doaj.org/article/bad3035cf3214b06a831b4d0364642d9
Autor:
Rui Lu, Ying-Guang Wang, Yunkun Qu, Shan-Xi Wang, Cheng Peng, Hongbo You, Wentao Zhu, Anmin Chen
Publikováno v:
Bone & Joint Research, Vol 12, Iss 4, Pp 259-273 (2023)
Aims: Osteoarthritis (OA) is a prevalent joint disorder with inflammatory response and cartilage deterioration as its main features. Dihydrocaffeic acid (DHCA), a bioactive component extracted from natural plant (gynura bicolor), has demonstrated ant
Externí odkaz:
https://doaj.org/article/8e2dec9b84224d96b5d0747e2c774266
Autor:
Yi He, Wei Wang, Haiting Zhou, Xiaojian Huang, Yinguang Wang, Yunkun Qu, Hao Cheng, Hongbo You
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Intervertebral disc degeneration, local lumbar segmental morphology changes, and atrophy of multifidus muscle have been considered to be associated with degenerative lumbar spondylolisthesis. However, there remains a great deal of controvers
Externí odkaz:
https://doaj.org/article/2aa78190b9f04b999a716ca98a403a57
Autor:
Shanxi Wang, Xuan Fang, Yunkun Qu, Rui Lu, Xiaojun Yu, Shaoze Jing, Qing Ding, Chaoxu Liu, Hua Wu, Yang Liu
Publikováno v:
Frontiers in Surgery, Vol 10 (2023)
BackgroundTo assess the clinical and radiographical outcomes of 3-level anterior cervical discectomy and fusion (ACDF) with a 3D-printed titanium cage in treating degenerative cervical spondylosis.MethodsIn this study, 25 patients with degenerative c
Externí odkaz:
https://doaj.org/article/44379130684c48e0838f0769ae550052
Autor:
Yi He, Haiting Zhou, Xiaojian Huang, Yunkun Qu, Yingguang Wang, Wenbin Pei, Rui Zhang, Sheng Chen, Hongbo You
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionTumor microenvironment (TME) has been shown to be extensively involved in tumor development. However, the dynamic change of TME components and their effects are still unclear. Here, we attempted to identify TME-related genes that could he
Externí odkaz:
https://doaj.org/article/c465bc62d5da445cac4a1626f84a533e
Publikováno v:
European Journal of Pharmacology. 952:175789
Autor:
Yunkun Qu, Yingguang Wang, Shanxi Wang, Xiaojun Yu, Yi He, Rui Lu, Sheng Chen, Cheng Meng, Hanqing Xu, Wenbin Pei, Bowei Ni, Rui Zhang, Xiaojian Huang, Hongbo You
Publikováno v:
Computers in Biology and Medicine. 160:106926
Autor:
Yi, He, Haiting, Zhou, Xiaojian, Huang, Yunkun, Qu, Yingguang, Wang, Wenbin, Pei, Rui, Zhang, Sheng, Chen, Hongbo, You
Publikováno v:
Frontiers in immunology. 13
Tumor microenvironment (TME) has been shown to be extensively involved in tumor development. However, the dynamic change of TME components and their effects are still unclear. Here, we attempted to identify TME-related genes that could help predict s