Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yunkun Lu"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Acute pancreatitis (AP) is currently among the most prevalent digestive diseases. The pathogenesis of AP remains elusive, and there is no specific treatment. Therefore, identifying novel therapeutic targets is imperative for effective manage
Externí odkaz:
https://doaj.org/article/892d71d0685e4511b670f9fe6844b43a
Publikováno v:
PeerJ, Vol 12, p e17861 (2024)
Background As a heterogeneous malignancy, breast cancer (BRCA) shows high incidence and mortality. Discovering novel molecular markers and developing reliable prognostic models may improve the survival of BCRA. Methods The RNA-seq data of BRCA patien
Externí odkaz:
https://doaj.org/article/ab217d91f0444d2f9f3c861f8d79f338
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Worldwide, Lung cancer is the leading cause of cancer-related death and poses a direct health threat, non-small cell lung cancer (NSCLC) is the most common type. In this study, we demonstrated that centrosomal protein 20 (CEP20) is upregulat
Externí odkaz:
https://doaj.org/article/f453a2b0061a4f4582597f17c72b6673
Autor:
Xiaojie Ma, Jie Cao, Ziyu Zhou, Yunkun Lu, Qin Li, Yan Jin, Guo Chen, Weiyun Wang, Wenyan Ge, Xi Chen, Zhensheng Hu, Xiao Shu, Qian Deng, Jiaqi Pu, Chengzhen Liang, Junfen Fu, Jianzhao Liu, Saiyong Zhu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Ma et al. profile the dynamic landscape of m6A during pancreatic differentiation, and identify ALKBH5 as an essential m6A regulator supporting pancreatic differentiation, indicating a role for m6A-mediated mRNA metabolism in cell-fate specification.
Externí odkaz:
https://doaj.org/article/496a2459e90a481ebe4a49760e2ab05a
Publikováno v:
Energies, Vol 15, Iss 19, p 7080 (2022)
In recent years, heat storage technology has attracted wide attention in the fields of renewable energy storage for its relatively high melting point, high heat storage capacity and economy, Na2CO3 and eutectic salt mixtures containing Na2CO3 are pro
Externí odkaz:
https://doaj.org/article/712cc6cc78894c3f8e7605bb67059a20
Publikováno v:
Materials, Vol 15, Iss 9, p 3350 (2022)
Fe-Si-Cr soft magnetic powder cores (SMCs), with high electrical resistivity, magnetic permeability, saturation magnetic induction, and good corrosion resistance, are widely applied to inductors, filters, choke coils, etc. However, with the developme
Externí odkaz:
https://doaj.org/article/719718fa22684fb79a76df88ab320399
Autor:
Yan Jin, Yunkun Lu, Lianyu Lin, Chao Liu, Xiaojie Ma, Xi Chen, Ziyu Zhou, Zhensheng Hu, Jiaqi Pu, Guo Chen, Qian Deng, Liling Jiang, Yuhan Li, Yulong Zhao, Hao Wang, Junfen Fu, Wei Li, Saiyong Zhu
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Chemistry-alone approach has recently been applied for incepting pluripotency in somatic cells, representing a breakthrough in biology. However, chemical reprogramming is hampered by low efficiency, and the underlying molecular mechanisms remain uncl
Autor:
Xiaojie Ma, Jie Cao, Ziyu Zhou, Yunkun Lu, Qin Li, Yan Jin, Guo Chen, Weiyun Wang, Wenyan Ge, Xi Chen, Zhensheng Hu, Xiao Shu, Qian Deng, Jiaqi Pu, Chengzhen Liang, Junfen Fu, Jianzhao Liu, Saiyong Zhu
Publikováno v:
Nature Communications. 13
Pancreatic differentiation from human pluripotent stem cells (hPSCs) provides promising avenues for investigating development and treating diseases. N6-methyladenosine (m6A) is the most prevalent internal messenger RNA (mRNA) modification and plays p
Autor:
Haifeng Zhang, Ying Ge, Yunkun Lu, Mengjie Yan, Jingcen Zhang, Hao Fu, Haiming Long, Pei Li, Yang Li, Chenzeng Zhang, Junjie Hao
Publikováno v:
Applied Surface Science. 611:155789
Autor:
Xiaojie Ma, Yunkun Lu, Ziyu Zhou, Qin Li, Xi Chen, Weiyun Wang, Yan Jin, Zhensheng Hu, Guo Chen, Qian Deng, Weina Shang, Hao Wang, Hongxing Fu, Xiangwei He, Xin-Hua Feng, Saiyong Zhu
Publikováno v:
Science advances. 8(8)
An unlimited source of human pancreatic β cells is in high demand. Even with recent advances in pancreatic differentiation from human pluripotent stem cells, major hurdles remain in large-scale and cost-effective production of functional β cells. H